Gene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans

Integrating Factor Analysis and a Transgenic Mouse Model to Reveal a Peripheral Blood Predictor of Breast Tumors

(2011) Heather G LaBreche et al.   BMC Medical Genomics

Expanding the Understanding of Biases in Development of Clinical-Grade Molecular Signatures: A Case Study in Acute Respiratory Viral Infections

(2011) Nikita I. Lytkin et al.   PLoS One

Disease Progression in Hemodynamically Stable Patients Presenting to the Emergency Department With Sepsis

(2010) Seth W. Glickman et al.   ACADEMIC EMERGENCY MEDICINE

Genome wide transcriptome profiling of a murine acute melioidosis model reveals new insights into how Burkholderia pseudomallei overcomes host innate immunity

(2010) Chui-Yoke Chin et al.   BMC GENOMICS

Detection of Viruses Via Statistical Gene Expression Analysis

(2010) Minhua Chen et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Diagnosis of Partial Body Radiation Exposure in Mice Using Peripheral Blood Gene Expression Profiles

(2010) Sarah K. Meadows et al.   PLoS One

Latent Factor Analysis to Discover Pathway-Associated Putative Segmental Aneuploidies in Human Cancers

(2010) Joseph E. Lucas et al.   PLoS Computational Biology

Two Genes on A/J Chromosome 18 Are Associated with Susceptibility to Staphylococcus aureus Infection by Combined Microarray and QTL Analyses

(2010) Sun-Hee Ahn et al.   PLoS Pathogens

Gene Expression Signatures Diagnose Influenza and Other Symptomatic Respiratory Viral Infections in Humans

(2009) Aimee K. Zaas et al.   Cell Host & Microbe

Initiation of Inappropriate Antimicrobial Therapy Results in a Fivefold Reduction of Survival in Human Septic Shock

(2009) Anand Kumar et al.   CHEST

Expression Signature Developed from a Complex Series of Mouse Models Accurately Predicts Human Breast Cancer Survival

(2009) M. He et al.   CLINICAL CANCER RESEARCH

Multiplex PCR To Diagnose Bloodstream Infections in Patients Admitted from the Emergency Department with Sepsis

(2009) Ephraim L. Tsalik et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Sepsis-induced human lymphocyte apoptosis and cytokine production in “humanized” mice

(2009) Jacqueline Unsinger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

High-Dimensional Sparse Factor Modeling: Applications in Gene Expression Genomics

(2009) Carlos M. Carvalho et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

A Genomic Strategy to Elucidate Modules of Oncogenic Pathway Signaling Networks

(2009) Jeffrey T. Chang et al.   MOLECULAR CELL

Enhanced Monocyte Response and Decreased Central Memory T Cells in Children with Invasive Staphylococcus aureus Infections

(2009) Monica I. Ardura et al.   PLoS One

A Bayesian Analysis Strategy for Cross-Study Translation of Gene Expression Biomarkers

(2009) Joseph Lucas et al.   Statistical Applications in Genetics and Molecular Biology

Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis

(2009) Rungnapa Pankla et al.   GENOME BIOLOGY

Immunological Mechanisms Underlying the Genetic Predisposition to Severe Staphylococcus aureus Infection in the Mouse Model

(2008) Maren von Köckritz-Blickwede et al.   AMERICAN JOURNAL OF PATHOLOGY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Gene-expression profiling of Gram-positive and Gram-negative sepsis in critically ill patients*

(2008) Benjamin M.P. Tang et al.   CRITICAL CARE MEDICINE

Animal models of sepsis: Why does preclinical efficacy fail to translate to the clinical setting?

(2008) Alex Dyson et al.   CRITICAL CARE MEDICINE

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY

Plasticity of the Systemic Inflammatory Response to Acute Infection during Critical Illness: Development of the Riboleukogram

(2008) Jonathan E. McDunn et al.   PLoS One

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

(2008) H. von Bernuth et al.   SCIENCE