Loss of Circulating CD4 T Cells with B Cell Helper Function during Chronic HIV Infection

CpG Oligonucleotides Enhance Proliferative and Effector Responses of B Cells in HIV-Infected Individuals

(2014) A. Malaspina et al.   JOURNAL OF IMMUNOLOGY

Circulating Precursor CCR7loPD-1hi CXCR5+ CD4+ T Cells Indicate Tfh Cell Activity and Promote Antibody Responses upon Antigen Reexposure

(2013) Jing He et al.   IMMUNITY

Distinct Memory CD4+ T Cells with Commitment to T Follicular Helper- and T Helper 1-Cell Lineages Are Generated after Acute Viral Infection

(2013) J. Scott Hale et al.   IMMUNITY

Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

(2013) Michela Locci et al.   IMMUNITY

HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration

(2013) Arik Cooper et al.   NATURE

Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses

(2013) F. Spensieri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T Follicular Helper Cell Dynamics in Germinal Centers

(2013) Z. Shulman et al.   SCIENCE

Induction of ICOS+CXCR3+CXCR5+ TH Cells Correlates with Antibody Responses to Influenza Vaccination

(2013) S.-E. Bentebibel et al.   Science Translational Medicine

Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009 H1N1/09 vaccine

(2012) S. Pallikkuth et al.   BLOOD

Expansion of HIV-specific T follicular helper cells in chronic HIV infection

(2012) Madelene Lindqvist et al.   JOURNAL OF CLINICAL INVESTIGATION

CD4 T follicular helper cell dynamics during SIV infection

(2012) Constantinos Petrovas et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-2 Requirement for Human Plasma Cell Generation: Coupling Differentiation and Proliferation by Enhancing MAPK-ERK Signaling

(2012) S. Le Gallou et al.   JOURNAL OF IMMUNOLOGY

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse

(2012) Katja Lüthje et al.   NATURE IMMUNOLOGY

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

(2011) Rimpei Morita et al.   IMMUNITY

Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells

(2011) Laura M. Fahey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CXCR5 Expressing Human Central Memory CD4 T Cells and Their Relevance for Humoral Immune Responses

(2011) N. Chevalier et al.   JOURNAL OF IMMUNOLOGY

Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection

(2011) Netanya G. Sandler et al.   JOURNAL OF INFECTIOUS DISEASES

Origins of CD4+ effector and central memory T cells

(2011) Marion Pepper et al.   NATURE IMMUNOLOGY

Human tonsil B-cell lymphoma 6 (BCL6)-expressing CD4+ T-cell subset specialized for B-cell help outside germinal centers

(2011) S.-E. Bentebibel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Late Interleukin-6 Escalates T Follicular Helper Cell Responses and Controls a Chronic Viral Infection

(2011) J. A. Harker et al.   SCIENCE

Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1

(2011) Iliyana Mikell et al.   PLoS Pathogens

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

(2010) Michelle A. Linterman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The elusive identity of T follicular helper cells

(2010) Di Yu et al.   TRENDS IN IMMUNOLOGY

Metabolic outcomes in a randomized trial of nucleoside, nonnucleoside and protease inhibitor-sparing regimens for initial HIV treatment

(2009) Richard H Haubrich et al.   AIDS

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12

(2009) Cindy S Ma et al.   IMMUNOLOGY AND CELL BIOLOGY

T follicular helper cells differentiate from Th2 cells in response to helminth antigens

(2009) Arielle Glatman Zaretsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Breadth of Human Immunodeficiency Virus-Specific Neutralizing Activity in Sera: Clustering Analysis and Association with Clinical Variables

(2009) N. A. Doria-Rose et al.   JOURNAL OF VIROLOGY

Interleukin 17 acts in synergy with B cell–activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus

(2009) Agnès Doreau et al.   NATURE IMMUNOLOGY

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

Altered expression of the receptor-ligand pair CXCR5/CXCL13 in B cells during chronic HIV-1 infection

(2008) A. Cagigi et al.   BLOOD

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

(2008) Roza I. Nurieva et al.   IMMUNITY

Class-Sparing Regimens for Initial Treatment of HIV-1 Infection

(2008) Sharon A. Riddler et al.   NEW ENGLAND JOURNAL OF MEDICINE