Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment

Recombinant Human Prion Protein Fragment 90–231, a Useful Model to Study Prion Neurotoxicity

(2012) Alessandro Corsaro et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

A  neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors

(2012) H. You et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Possible role for Ca2+ in the pathophysiology of the prion protein?

(2011) Caterina Peggion et al.   BIOFACTORS

Design and Production of a Chimeric Resilin-, Elastin-, and Collagen-Like Engineered Polypeptide

(2011) Angelo Bracalello et al.   BIOMACROMOLECULES

Amyloid β peptide oligomers directly activate NMDA receptors

(2011) Laura Texidó et al.   CELL CALCIUM

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases

(2011) Malin K. Sandberg et al.   NATURE

The pathological prion protein forms ionic conductance in lipid bilayer

(2011) Daniele Paulis et al.   NEUROCHEMISTRY INTERNATIONAL

Prion protein at the crossroads of physiology and disease

(2011) Emiliano Biasini et al.   TRENDS IN NEUROSCIENCES

Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction

(2011) S Thellung et al.   Cell Death & Disease

Amyloid β oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors

(2010) Elena Alberdi et al.   CELL CALCIUM

High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein

(2010) Alessandro Corsaro et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Efficacy of Novel Acridine Derivatives in the Inhibition of hPrP90-231 Prion Protein Fragment Toxicity

(2010) Valentina Villa et al.   NEUROTOXICITY RESEARCH

Glutamate, excitotoxicity, and programmed cell death in parkinson disease

(2009) W. Michael Caudle et al.   EXPERIMENTAL NEUROLOGY

Loss of Cerebellar Granule Neurons Is Associated With Punctate but Not With Large Focal Deposits of Prion Protein in Creutzfeldt-Jakob Disease

(2009) Baptiste A. Faucheux et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

GABAA receptors of cerebellar granule cells in culture: explanation of overall insensitivity to ethanol

(2009) E. Gatta et al.   NEUROSCIENCE

Dual Modulation of ERK1/2 and p38 MAP Kinase Activities Induced by Minocycline Reverses the Neurotoxic Effects of the Prion Protein Fragment 90–231

(2009) Alessandro Corsaro et al.   NEUROTOXICITY RESEARCH

Stress-protective signalling of prion protein is corrupted by scrapie prions

(2008) Angelika S Rambold et al.   EMBO JOURNAL

Memantine protects rat cortical cultured neurons against β-amyloid-induced toxicity by attenuating tau phosphorylation

(2008) M. S. Song et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Nonspecific Interaction of Prefibrillar Amyloid Aggregates with Glutamatergic Receptors Results in Ca2+Increase in Primary Neuronal Cells

(2008) Francesca Pellistri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES