Interferon-beta therapy in multiple sclerosis: the short-term and long-term effects on the patients’ individual gene expression in peripheral blood

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An Inventory of Short Term and Long Term Changes in Gene Expression Under Interferon β Treatment of Relapsing Remitting MS Patients

(2012) Brigitte K. Paap et al.   CURRENT PHARMACEUTICAL DESIGN

Elevated type I interferon-like activity in a subset of multiple sclerosis patients: molecular basis and clinical relevance

(2012) Alexander Hundeshagen et al.   Journal of Neuroinflammation

A randomised, double blind, placebo controlled trial with vitamin D3as an add on treatment to interferon β-1b in patients with multiple sclerosis

(2012) Merja Soilu-Hänninen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Integration of MicroRNA Databases to Study MicroRNAs Associated with Multiple Sclerosis

(2012) Charlotte Angerstein et al.   MOLECULAR NEUROBIOLOGY

AP-1 Mediated Transcriptional Repression of Matrix Metalloproteinase-9 by Recruitment of Histone Deacetylase 1 in Response to Interferon β

(2012) Megan L. Mittelstadt et al.   PLoS One

Development of resistance to biologic therapies with reference to IFN- 

(2012) R. A. Farrell et al.   RHEUMATOLOGY

Capture, crawl, cross: the T cell code to breach the blood–brain barriers

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Classical immunomodulatory therapy in multiple sclerosis: how it acts, how it works

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Immune-mediated CNS diseases: A review on nosological classification and clinical features

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Viperin: A Multifunctional, Interferon-Inducible Protein that Regulates Virus Replication

(2011) Jun-Young Seo et al.   Cell Host & Microbe

Natural killer cell phenotype and clinical response to interferon-beta therapy in multiple sclerosis

(2011) J.E. Martínez-Rodríguez et al.   CLINICAL IMMUNOLOGY

PEGylation of Interferon-β-1a

(2011) Bernd C. Kieseier et al.   CNS DRUGS

Sensing of viral nucleic acids by RIG-I: From translocation to translation

(2011) Andreas Schmidt et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Identification of a new susceptibility variant for multiple sclerosis in OAS1 by population genetics analysis

(2011) Rachele Cagliani et al.   HUMAN GENETICS

Structure of Myxovirus Resistance Protein A Reveals Intra- and Intermolecular Domain Interactions Required for the Antiviral Function

(2011) Song Gao et al.   IMMUNITY

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Stalk Domain of the Dynamin-like MxA GTPase Protein Mediates Membrane Binding and Liposome Tubulation via the Unstructured L4 Loop

(2011) Alexander von der Malsburg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unexpected Role for Granzyme K in CD56bright NK Cell-Mediated Immunoregulation of Multiple Sclerosis

(2011) W. Jiang et al.   JOURNAL OF IMMUNOLOGY

Opposite effects of interferon-beta on new B and T cell release from production sites in multiple sclerosis patients

(2011) Cinzia Zanotti et al.   JOURNAL OF NEUROIMMUNOLOGY

Biomarkers of disease activity in multiple sclerosis

(2011) Jerome J. Graber et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Efficacy and safety of subcutaneous interferon beta-1a in relapsing–remitting multiple sclerosis: Further outcomes from the IMPROVE study

(2011) Nicola De Stefano et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

Determinants of interferon β efficacy in patients with multiple sclerosis

(2011) Joep Killestein et al.   Nature Reviews Neurology

The UCSC Genome Browser database: extensions and updates 2011

(2011) T. R. Dreszer et al.   NUCLEIC ACIDS RESEARCH

Sieving treatment biomarkers from blood gene-expression profiles: a pharmacogenomic update on two types of multiple sclerosis therapy

(2011) Robert H Goertsches et al.   PHARMACOGENOMICS

Glatiramer Acetate Treatment Normalizes Deregulated microRNA Expression in Relapsing Remitting Multiple Sclerosis

(2011) Anne Waschbisch et al.   PLoS One

Reassessment of Blood Gene Expression Markers for the Prognosis of Relapsing-Remitting Multiple Sclerosis

(2011) Michael Hecker et al.   PLoS One

A Family of IFN- -Inducible 65-kD GTPases Protects Against Bacterial Infection

(2011) B.-H. Kim et al.   SCIENCE

Systematic review of genome-wide expression studies in multiple sclerosis

(2011) A. K. Kemppinen et al.   BMJ Open

Inhibition of Endogenous Interferon Beta by Neutralizing Antibodies Against Recombinant Interferon Beta

(2010) Ajith Sominanda et al.   ARCHIVES OF NEUROLOGY

Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis

(2010) P. Serrano-Fernández et al.   AUTOIMMUNITY

Viral triggers of multiple sclerosis

(2010) Kristina Kakalacheva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

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(2010) M. E. Smoot et al.   BIOINFORMATICS

Evidence for a two-stage disability progression in multiple sclerosis

(2010) E. Leray et al.   BRAIN

Type I interferon (IFN-α/β) rescues B-lymphocytes from apoptosis via PI3Kδ/Akt, Rho-A, NFκB and Bcl-2/BclXL

(2010) Gamal Badr et al.   CELLULAR IMMUNOLOGY

Therapy of MS

(2010) Reza Vosoughi et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

New developments in the induction and antiviral effectors of type I interferon

(2010) Su-Yang Liu et al.   CURRENT OPINION IN IMMUNOLOGY

IFN-  Inhibits Dendritic Cell Migration through STAT-1-Mediated Transcriptional Suppression of CCR7 and Matrix Metalloproteinase 9

(2010) J.-H. Yen et al.   JOURNAL OF IMMUNOLOGY

Major Differences in the Responses of Primary Human Leukocyte Subsets to IFN- 

(2010) A. H. H. van Boxel-Dezaire et al.   JOURNAL OF IMMUNOLOGY

Differential Gene Expression and Translational Approaches to Identify Biomarkers of Interferon Beta Activity in Multiple Sclerosis

(2010) Ed Croze   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The Role of Protein Kinase R in the Interferon Response

(2010) Agnieszka Pindel et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Interferon-Stimulated Gene 15 and the Protein ISGylation System

(2010) Dongxian Zhang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Human MxA Protein: An Interferon-Induced Dynamin-Like GTPase with Broad Antiviral Activity

(2010) Otto Haller et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The ISG56/IFIT1 Gene Family

(2010) Volker Fensterl et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Alterations in serum MMP-8, MMP-9, IL-12p40 and IL-23 in multiple sclerosis patients treated with interferon-β1b

(2010) JS Alexander et al.   Multiple Sclerosis Journal

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

OAS1: A multiple sclerosis susceptibility gene that influences disease severity

(2010) M. O'Brien et al.   NEUROLOGY

Review: The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity - a tale of conflict and conundrum

(2010) M. Müller et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Long-term genome-wide blood RNA expression profiles yield novel molecular response candidates for IFN-β-1b treatment in relapsing remitting MS

(2010) Robert H Goertsches et al.   PHARMACOGENOMICS

Network analysis of transcriptional regulation in response to intramuscular interferon-β-1a multiple sclerosis treatment

(2010) M Hecker et al.   PHARMACOGENOMICS JOURNAL

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(2010) Fengxin Lu et al.   THROMBOSIS AND HAEMOSTASIS

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(2010) M. Safran et al.   Database-The Journal of Biological Databases and Curation

Enhancement of Chemokine Expression by Interferon Beta Therapy in Patients With Multiple Sclerosis

(2009) Sabine Cepok   ARCHIVES OF NEUROLOGY

CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets

(2009) J. Yu et al.   BLOOD

A HaemAtlas: characterizing gene expression in differentiated human blood cells

(2009) Nicholas A. Watkins et al.   BLOOD

Integrative modeling of transcriptional regulation in response to antirheumatic therapy

(2009) Michael Hecker et al.   BMC BIOINFORMATICS

A type I interferon signature in monocytes is associated with poor response to interferon-β in multiple sclerosis

(2009) M. Comabella et al.   BRAIN

Complement and its role in innate and adaptive immune responses

(2009) Jason R Dunkelberger et al.   CELL RESEARCH

High-dose, high-frequency recombinant interferon beta-1a in the treatment of multiple sclerosis

(2009) Hans-Peter Hartung   EXPERT OPINION ON PHARMACOTHERAPY

Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein

(2009) Yasuhiro Itsui et al.   HEPATOLOGY

The nonpolymorphic MHC Qa-1bmediates CD8+T cell surveillance of antigen-processing defects

(2009) Cláudia C. Oliveira et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Monitoring of multiple sclerosis immunotherapy

(2009) Robert H. Goertsches et al.   JOURNAL OF NEUROLOGY

Matrix metalloproteinase-9 and matrix metalloproteinase-2 as biomarkers of various courses in multiple sclerosis

(2009) Y Benešová et al.   Multiple Sclerosis Journal

Regulation of matrix metalloproteinases and their inhibitors by interferon-β: a longitudinal study in multiple sclerosis patients

(2009) F Bernal et al.   Multiple Sclerosis Journal

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(2009) Rebecca Toroney et al.   Nature Chemical Biology

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

(2009) Harukazu Suzuki et al.   NATURE GENETICS

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(2009) S. Dhib-Jalbut et al.   NEUROLOGY

Increased blood vessel density and endothelial cell proliferation in multiple sclerosis cerebral white matter

(2009) Janet E. Holley et al.   NEUROSCIENCE LETTERS

Regulation and Functions of Blimp-1 in T and B Lymphocytes

(2008) Gislâine Martins et al.   Annual Review of Immunology

The TRANSFAC project as an example of framework technology that supports the analysis of genomic regulation

(2008) E. Wingender   BRIEFINGS IN BIOINFORMATICS

Basic and escalating immunomodulatory treatments in multiple sclerosis: Current therapeutic recommendations

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(2008) Alastair Compston et al.   LANCET

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Expression and regulation of IFN /  receptor in IFN -treated patients with multiple sclerosis

(2008) F. Gilli et al.   NEUROLOGY

Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL

(2008) Y. Pekarsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA