Multi-target, Neuroprotective and Neurorestorative M30 Improves Cognitive Impairment and Reduces Alzheimer's-Like Neuropathology and Age-Related Alterations in Mice

Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment

(2017) Mark A. Smith et al.   JOURNAL OF ALZHEIMERS DISEASE

The Novel Multi-Target Iron Chelating-Radical Scavenging Compound M30 Possesses Beneficial Effects on Major Hallmarks of Alzheimer's Disease

(2012) Lana Kupershmidt et al.   ANTIOXIDANTS & REDOX SIGNALING

Neuroprotection by the multitarget iron chelator M30 on age-related alterations in mice

(2012) Lana Kupershmidt et al.   MECHANISMS OF AGEING AND DEVELOPMENT

From Antioxidant Chelators to Site-Activated Multi-Target Chelators Targeting Hypoxia Inducing Factor, Beta-Amyloid, Acetylcholinesterase and Monoamine Oxidase A/B

(2012) H. Zheng et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

The role of metallobiology and amyloid-β peptides in Alzheimer’s disease

(2011) Blaine R. Roberts et al.   JOURNAL OF NEUROCHEMISTRY

Novel molecular targets of the neuroprotective/neurorescue multimodal iron chelating drug M30 in the mouse brain

(2011) L. Kupershmidt et al.   NEUROSCIENCE

Mitochondria and Hypoxia-induced Gene Expression Mediated by Hypoxia-inducible Factors

(2010) Angela Chavez et al.   Annals of the New York Academy of Sciences

Neuroprotective Multifunctional Iron Chelators: From Redox-Sensitive Process to Novel Therapeutic Opportunities

(2010) Orly Weinreb et al.   ANTIOXIDANTS & REDOX SIGNALING

Prolyl 4-hydroxylase

(2010) Kelly L. Gorres et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Up-Regulation of Hypoxia-Inducible Factor (HIF)-1α and HIF-Target Genes in Cortical Neurons by the Novel Multifunctional Iron Chelator Anti-Alzheimer Drug, M30

(2010) Y. Avramovich-Tirosh et al.   Current Alzheimer Research

Novel drug targets based on metallobiology of Alzheimer's disease

(2010) Sanghamitra Bandyopadhyay et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Prolyl Hydroxylase Domain Inhibitors: A Route to HIF Activation and Neuroprotection

(2009) Sarah K. Harten et al.   ANTIOXIDANTS & REDOX SIGNALING

Prolyl Hydroxylases and Therapeutics

(2009) Thomas G. Smith et al.   ANTIOXIDANTS & REDOX SIGNALING

Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis

(2009) Lana Kupershmidt et al.   FASEB JOURNAL

Physiological and Pathological Role of Alpha-synuclein in Parkinson’s Disease Through Iron Mediated Oxidative Stress; The Role of a Putative Iron-responsive Element

(2009) David Olivares et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Limited Potentiation of Blood Pressure in Response to Oral Tyramine by the Anti-Parkinson Brain Selective Multifunctional Monoamine Oxidase-AB Inhibitor, M30

(2009) Shunit Gal et al.   NEUROTOXICITY RESEARCH

Restoration of Nigrostriatal Dopamine Neurons in Post-MPTP Treatment by the Novel Multifunctional Brain-Permeable Iron Chelator-Monoamine Oxidase Inhibitor Drug, M30

(2009) Shunit Gal et al.   NEUROTOXICITY RESEARCH