Analysis of single-cell cytokine secretion reveals a role for paracrine signaling in coordinating macrophage responses to TLR4 stimulation
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Analysis of single-cell cytokine secretion reveals a role for paracrine signaling in coordinating macrophage responses to TLR4 stimulation
Authors
Keywords
-
Journal
Science Signaling
Volume 8, Issue 381, Pages ra59-ra59
Publisher
American Association for the Advancement of Science (AAAS)
Online
2015-06-17
DOI
10.1126/scisignal.aaa2155
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Fold Change of Nuclear NF-κB Determines TNF-Induced Transcription in Single Cells
- (2014) Robin E.C. Lee et al. MOLECULAR CELL
- Single-cell RNA-seq reveals dynamic paracrine control of cellular variation
- (2014) Alex K. Shalek et al. NATURE
- The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
- (2014) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- Single-cell technologies for monitoring immune systems
- (2014) Pratip K Chattopadhyay et al. NATURE IMMUNOLOGY
- Secreting and Sensing the Same Molecule Allows Cells to Achieve Versatile Social Behaviors
- (2014) H. Youk et al. SCIENCE
- Switching of the Relative Dominance Between Feedback Mechanisms in Lipopolysaccharide-Induced NF- B Signaling
- (2014) M.-H. Sung et al. Science Signaling
- High-Throughput Secretomic Analysis of Single Cells to Assess Functional Cellular Heterogeneity
- (2013) Yao Lu et al. ANALYTICAL CHEMISTRY
- Anatomically Restricted Synergistic Antiviral Activities of Innate and Adaptive Immune Cells in the Skin
- (2013) Heather D. Hickman et al. Cell Host & Microbe
- IL-1 Promotes Antimicrobial Immunity in Macrophages by Regulating TNFR Signaling and Caspase-3 Activation
- (2013) P. Jayaraman et al. JOURNAL OF IMMUNOLOGY
- Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells
- (2013) Alex K. Shalek et al. NATURE
- Nod2-Induced Autocrine Interleukin-1 Alters Signaling by ERK and p38 to Differentially Regulate Secretion of Inflammatory Cytokines
- (2012) Matija Hedl et al. GASTROENTEROLOGY
- IL-6 Amplifier, NF- B-Triggered Positive Feedback for IL-6 Signaling, in Grafts Is Involved in Allogeneic Rejection Responses
- (2012) J. Lee et al. JOURNAL OF IMMUNOLOGY
- Inhibition of JAKs in Macrophages Increases Lipopolysaccharide-Induced Cytokine Production by Blocking IL-10-Mediated Feedback
- (2012) M. J. Pattison et al. JOURNAL OF IMMUNOLOGY
- Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response
- (2012) Ulfert Rand et al. Molecular Systems Biology
- Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells
- (2012) F. Moledina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IL-10-induced microRNA-187 negatively regulates TNF- , IL-6, and IL-12p40 production in TLR4-stimulated monocytes
- (2012) M. Rossato et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stochastic Expression of the Interferon-β Gene
- (2012) Mingwei Zhao et al. PLOS BIOLOGY
- Distinct Roles for Nod2 Protein and Autocrine Interleukin-1β in Muramyl Dipeptide-induced Mitogen-activated Protein Kinase Activation and Cytokine Secretion in Human Macrophages
- (2011) Matija Hedl et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Immune Responses by Prostaglandin E2
- (2011) P. Kalinski JOURNAL OF IMMUNOLOGY
- A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells
- (2011) Chao Ma et al. NATURE MEDICINE
- Polyfunctional responses by human T cells result from sequential release of cytokines
- (2011) Q. Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Secretory Mediators Regulate Nod2-Induced Tolerance in Human Macrophages
- (2010) Matija Hedl et al. GASTROENTEROLOGY
- Patterns of basal signaling heterogeneity can distinguish cellular populations with different drug sensitivities
- (2010) Dinesh Kumar Singh et al. Molecular Systems Biology
- Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression
- (2010) Luca Mariani et al. Molecular Systems Biology
- Population robustness arising from cellular heterogeneity
- (2010) P. Paszek et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pairwise network mechanisms in the host signaling response to coxsackievirus B3 infection
- (2010) F. S. Garmaroudi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of Adaptive Immunity by the Innate Immune System
- (2010) A. Iwasaki et al. SCIENCE
- On-Chip Activation and Subsequent Detection of Individual Antigen-Specific T Cells
- (2009) Qing Song et al. ANALYTICAL CHEMISTRY
- Population context determines cell-to-cell variability in endocytosis and virus infection
- (2009) Berend Snijder et al. NATURE
- Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
- (2009) Sabrina L. Spencer et al. NATURE
- A Noisy Paracrine Signal Determines the Cellular NF- B Response to Lipopolysaccharide
- (2009) T. K. Lee et al. Science Signaling
- Suppression of LPS-Induced TNF- Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105
- (2009) E. A. Wall et al. Science Signaling
- TNF -induced GM-CSF release from human airway smooth muscle cells depends on activation of an ET-1 autoregulatory positive feedback mechanism
- (2009) J Knobloch et al. THORAX
- Determining biological noise via single cell analysis
- (2008) Edgar A. Arriaga ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction
- (2008) Hideki Ogura et al. IMMUNITY
- Transcriptome-wide noise controls lineage choice in mammalian progenitor cells
- (2008) Hannah H. Chang et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation