Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response

Stochastic Expression of the Interferon-β Gene

(2012) Mingwei Zhao et al.   PLOS BIOLOGY

Stochastic Receptor Expression Determines Cell Fate upon Interferon Treatment

(2011) D. Levin et al.   MOLECULAR AND CELLULAR BIOLOGY

Origins of regulated cell-to-cell variability

(2011) Berend Snijder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of Cell-to-Cell Variability in Activating a Positive Feedback Antiviral Response in Human Dendritic Cells

(2011) Jianzhong Hu et al.   PLoS One

Failure to activate the IFN-β promoter by a paramyxovirus lacking an interferon antagonist

(2011) M.J. Killip et al.   VIROLOGY

The transcriptional code of human IFN-β gene expression

(2010) Ethan Ford et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

Viral tricks to grid-lock the type I interferon system

(2010) Gijs A Versteeg et al.   CURRENT OPINION IN MICROBIOLOGY

Activation of host pattern recognition receptors by viruses

(2010) Kiva Brennan et al.   CURRENT OPINION IN MICROBIOLOGY

Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling

(2010) Tim Maiwald et al.   FEBS Journal

Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair

(2010) Martijn S. Luijsterburg et al.   JOURNAL OF CELL BIOLOGY

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

Novel Nonviral Bioassays for Mouse Type I and Type III Interferon

(2010) Daniela Kugel et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Temporal and Spatial Resolution of Type I and III Interferon Responses In Vivo

(2010) J. E. Pulverer et al.   JOURNAL OF VIROLOGY

Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression

(2010) Luca Mariani et al.   Molecular Systems Biology

Measurement of single-cell dynamics

(2010) David G. Spiller et al.   NATURE

Heterocellular induction of interferon by negative-sense RNA viruses

(2010) S. Chen et al.   VIROLOGY

Virus-Infection or 5′ppp-RNA Activates Antiviral Signal through Redistribution of IPS-1 Mediated by MFN1

(2010) Kazuhide Onoguchi et al.   PLoS Pathogens

Cutting Edge: TLR-Dependent Viral Recognition Along with Type I IFN Positive Feedback Signaling Masks the Requirement of Viral Replication for IFN-  Production in Plasmacytoid Dendritic Cells

(2009) Y. Kumagai et al.   JOURNAL OF IMMUNOLOGY

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

(2009) Sabrina L. Spencer et al.   NATURE

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Virus Infection Induces NF-κB-Dependent Interchromosomal Associations Mediating Monoallelic IFN-β Gene Expression

(2008) Effie Apostolou et al.   CELL

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS

Variability and Robustness in T Cell Activation from Regulated Heterogeneity in Protein Levels

(2008) O. Feinerman et al.   SCIENCE