Viral entry route determines how human plasmacytoid dendritic cells produce type I interferons

TLR ligands upregulate RIG-I expression in human plasmacytoid dendritic cells in a type I IFN-independent manner

(2014) Attila Szabo et al.   IMMUNOLOGY AND CELL BIOLOGY

Attenuation of Respiratory Syncytial Virus-Induced and RIG-I-Dependent Type I IFN Responses in Human Neonates and Very Young Children

(2014) N. Marr et al.   JOURNAL OF IMMUNOLOGY

Efficient Sensing of Infected Cells in Absence of Virus Particles by Blasmacytoid Dendritic Cells Is Blocked by the Viral Ribonuclease Erns

(2014) Sylvie Python et al.   PLoS Pathogens

I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection

(2013) Alessandra Mancino et al.   EMBO JOURNAL

A Novel IRAK1-IKK  Signaling Axis Limits the Activation of TAK1-IKK  Downstream of TLR3

(2013) D. Bruni et al.   JOURNAL OF IMMUNOLOGY

Melanoma Differentiation-Associated Gene 5 Senses Hepatitis B Virus and Activates Innate Immune Signaling To Suppress Virus Replication

(2013) H.-L. Lu et al.   JOURNAL OF IMMUNOLOGY

Viral Membrane Fusion and Nucleocapsid Delivery into the Cytoplasm are Distinct Events in Some Flaviviruses

(2013) Adel M. Nour et al.   PLoS Pathogens

Hepatitis C Virus Pathogen Associated Molecular Pattern (PAMP) Triggers Production of Lambda-Interferons by Human Plasmacytoid Dendritic Cells

(2013) Amy E. L. Stone et al.   PLoS Pathogens

A Virological View of Innate Immune Recognition

(2012) Akiko Iwasaki   Annual Review of Microbiology

Plasmacytoid Dendritic Cells Are Productively Infected and Activated through TLR-7 Early after Arenavirus Infection

(2012) Mónica Macal et al.   Cell Host & Microbe

Short-Range Exosomal Transfer of Viral RNA from Infected Cells to Plasmacytoid Dendritic Cells Triggers Innate Immunity

(2012) Marlène Dreux et al.   Cell Host & Microbe

CD81/CD9 tetraspanins aid plasmacytoid dendritic cells in recognition of hepatitis C virus-infected cells and induction of interferon-alpha

(2012) Shuye Zhang et al.   HEPATOLOGY

Plasmacytoid Dendritic Cells: Recent Progress and Open Questions

(2011) Boris Reizis et al.   Annual Review of Immunology

Regulation of RLR-mediated innate immune signaling – It is all about keeping the balance

(2011) Katharina Eisenächer et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

IL-1R-Associated Kinase-1 Mediates Protein Kinase C -Induced IL-1  Production in Monocytes

(2011) R. L. Tiwari et al.   JOURNAL OF IMMUNOLOGY

Distinctive TLR7 Signaling, Type I IFN Production, and Attenuated Innate and Adaptive Immune Responses to Yellow Fever Virus in a Primate Reservoir Host

(2011) J. N. Mandl et al.   JOURNAL OF IMMUNOLOGY

Innate Sensing of Foamy Viruses by Human Hematopoietic Cells

(2011) R. Rua et al.   JOURNAL OF VIROLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

The TRAF-associated protein TANK facilitates cross-talk within the I B kinase family during Toll-like receptor signaling

(2011) K. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The interaction of flavivirus M protein with light chain Tctex-1 of human dynein plays a role in late stages of virus replication

(2011) Jean-Baptiste Brault et al.   VIROLOGY

Innate Sensing of HIV-Infected Cells

(2011) Alice Lepelley et al.   PLoS Pathogens

A Genomic Approach to Human Autoimmune Diseases

(2010) Virginia Pascual et al.   Annual Review of Immunology

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

Immune Complex-Mediated Cell Activation from Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients Elaborate Different Requirements for IRAK1/4 Kinase Activity across Human Cell Types

(2010) E. Y. Chiang et al.   JOURNAL OF IMMUNOLOGY

Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection

(2010) K. Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Flaviviruses Activate and Suppress the Interferon Response

(2010) Jorge L. Muñoz-Jordán et al.   Viruses-Basel

Pathogenesis of Flavivirus Infections: Using and Abusing the Host Cell

(2009) Maria-Dolores Fernandez-Garcia et al.   Cell Host & Microbe

Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cells

(2009) Serena Chang et al.   HEPATOLOGY

Simultaneous Cell-to-Cell Transmission of Human Immunodeficiency Virus to Multiple Targets through Polysynapses

(2009) D. Rudnicka et al.   JOURNAL OF VIROLOGY

A Mouse Model for Studying Viscerotropic Disease Caused by Yellow Fever Virus Infection

(2009) Kathryn C. Meier et al.   PLoS Pathogens

Development of TLR inhibitors for the treatment of autoimmune diseases

(2008) Franck J. Barrat et al.   IMMUNOLOGICAL REVIEWS

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

(2008) Denis Gaucher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1

(2008) Huazhang An et al.   NATURE IMMUNOLOGY

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY

Leishmania-Induced IRAK-1 Inactivation Is Mediated by SHP-1 Interacting with an Evolutionarily Conserved KTIM Motif

(2008) Issa Abu-Dayyeh et al.   PLoS Neglected Tropical Diseases