RNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processes

Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells

(2012) Eleftherios Sachlos et al.   CELL

Alterations in the ribosomal machinery in cancer and hematologic disorders

(2012) Niraj Shenoy et al.   Journal of Hematology & Oncology

MLL–AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny

(2012) S J Horton et al.   LEUKEMIA

Immunohistochemical Analysis of Monocytic Leukemias

(2011) Jeffery M. Klco et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L

(2011) Kathrin M. Bernt et al.   CANCER CELL

Activation of the Aryl Hydrocarbon Receptor AhR Promotes Retinoic Acid-Induced Differentiation of Myeloblastic Leukemia Cells by Restricting Expression of the Stem Cell Transcription Factor Oct4

(2011) R. P. Bunaciu et al.   CANCER RESEARCH

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance

(2011) J. Zuber et al.   GENES & DEVELOPMENT

Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia

(2011) B. V. Balgobind et al.   HAEMATOLOGICA

Trends in the exploitation of novel drug targets

(2011) Mathias Rask-Andersen et al.   NATURE REVIEWS DRUG DISCOVERY

Expression profiling of cytogenetically normal acute myeloid leukemia identifies MicroRNAs that target genes involved in monocytic differentiation

(2010) Mark Lutherborrow et al.   AMERICAN JOURNAL OF HEMATOLOGY

Extracellular Signal-regulated Kinase 8 (ERK8) Controls Estrogen-related Receptor α (ERRα) Cellular Localization and Inhibits Its Transcriptional Activity

(2010) Matteo Rossi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Developmentally induced Mll1 loss reveals defects in postnatal haematopoiesis

(2010) T Gan et al.   LEUKEMIA

NCBI GEO: archive for functional genomics data sets--10 years on

(2010) T. Barrett et al.   NUCLEIC ACIDS RESEARCH

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

Differentiation therapy of leukemia: 3 decades of development

(2009) D. Nowak et al.   BLOOD

Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study

(2009) B. V. Balgobind et al.   BLOOD

Genomic Antagonism between Retinoic Acid and Estrogen Signaling in Breast Cancer

(2009) Sujun Hua et al.   CELL

The molecular biology of mixed lineage leukemia

(2009) R. K. Slany   HAEMATOLOGICA

Structure of the MLL CXXC domain–DNA complex and its functional role in MLL-AF9 leukemia

(2009) Tomasz Cierpicki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Malignant Transformation Initiated by Mll-AF9: Gene Dosage and Critical Target Cells

(2008) Weili Chen et al.   CANCER CELL

MLLT3 Regulates Early Human Erythroid and Megakaryocytic Cell Fate

(2008) Cristina Pina et al.   Cell Stem Cell

Sensors, Transducers, and Effectors That Regulate Cell Size and Shape

(2008) Mirkka Koivusalo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tethering Telomeric Double- and Single-stranded DNA-binding Proteins Inhibits Telomere Elongation

(2008) Katherine T. Etheridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression

(2008) F. E. Erfurth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights from clinical studies into the role of the MLL gene in infant and childhood leukemia

(2007) Tanzina Chowdhury et al.   BLOOD CELLS MOLECULES AND DISEASES