MLL–AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny

An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model

(2012) R. J. Bergerson et al.   BLOOD

Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma

(2012) R. W. J. Groen et al.   BLOOD

Hematopoietic Stem Cell Subtypes Expand Differentially during Development and Display Distinct Lymphopoietic Programs

(2012) Claudia Benz et al.   Cell Stem Cell

Polycomb repressive complex 2 is required for MLL-AF9 leukemia

(2012) T. Neff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pathogenesis of Mixed-Lineage Leukemia

(2011) Andrew G. Muntean et al.   Annual Review of Pathology-Mechanisms of Disease

Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia

(2011) B. Mizukawa et al.   BLOOD

Modeling human infant MLL leukemia in mice: leukemia from fetal liver differs from that originating in postnatal marrow

(2011) W. Chen et al.   BLOOD

Common and Overlapping Oncogenic Pathways Contribute to the Evolution of Acute Myeloid Leukemias

(2011) B. T. Kvinlaug et al.   CANCER RESEARCH

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

(2011) Noa Novershtern et al.   CELL

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance

(2011) J. Zuber et al.   GENES & DEVELOPMENT

Stem cell gene expression programs influence clinical outcome in human leukemia

(2011) Kolja Eppert et al.   NATURE MEDICINE

BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells

(2010) A. Rizo et al.   BLOOD

β-Catenin Mediates the Establishment and Drug Resistance of MLL Leukemic Stem Cells

(2010) Jenny Yeung et al.   CANCER CELL

A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs

(2010) Jonghwan Kim et al.   CELL

The Wnt/ -Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML

(2010) Y. Wang et al.   SCIENCE

Transformation from Committed Progenitor to Leukemia Stem Cells

(2009) Andrei V. Krivtsov et al.   Annals of the New York Academy of Sciences

Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells

(2009) Tim C.P. Somervaille et al.   Cell Stem Cell

Mouse models of human AML accurately predict chemotherapy response

(2009) J. Zuber et al.   GENES & DEVELOPMENT

HOXA9 is required for survival in human MLL-rearranged acute leukemias

(2008) J. Faber et al.   BLOOD

Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities

(2008) S. J. Horton et al.   BLOOD

Abundant anti-apoptotic BCL-2 is a molecular target in leukaemias with t(4;11) translocation

(2008) Blaine W. Robinson et al.   BRITISH JOURNAL OF HAEMATOLOGY

Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia

(2008) Junping Wei et al.   CANCER CELL

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells

(2008) David J. Wong et al.   Cell Stem Cell