Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis

Casein Kinase 1 Epsilon Expression Predicts Poorer Prognosis in Low T-Stage Oral Cancer Patients

(2014) Shu-Hui Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia

(2014) Marcus Järås et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Casein Kinase 1 1 Inhibits the RIG-I/TLR Signaling Pathway through Phosphorylating p65 and Promoting Its Degradation

(2014) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis

(2014) Yoshimi Endo Greer et al.   MOLECULAR BIOLOGY OF THE CELL

Targeted BRAF Inhibition Impacts Survival in Melanoma Patients with High Levels of Wnt/β-Catenin Signaling

(2014) Andy J. Chien et al.   PLoS One

Mammalian sterile 20-like kinase 1/2 inhibits the Wnt/β-catenin signalling pathway by directly binding casein kinase 1ε

(2013) Fei Xu et al.   BIOCHEMICAL JOURNAL

Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties

(2013) Mathieu Bibian et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Casein kinase 1/Checkpoint kinase 1 pyrazolo-pyridine protein kinase inhibitor as novel activator of the p53 pathway

(2013) Anne-Sophie Huart et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Integral analysis of p53 and its value as prognostic factor in sporadic colon cancer

(2013) Arantza Fariña Sarasqueta et al.   BMC CANCER

A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism

(2013) Ariel Pribluda et al.   CANCER CELL

CK1 Is Required for a Mitotic Checkpoint that Delays Cytokinesis

(2013) Alyssa E. Johnson et al.   CURRENT BIOLOGY

Control of Epithelial Cell Migration and Invasion by the IKKβ- and CK1α-Mediated Degradation of RAPGEF2

(2013) Roberto Magliozzi et al.   DEVELOPMENTAL CELL

Changes in tau phosphorylation in hibernating rodents

(2013) Gonzalo León-Espinosa et al.   JOURNAL OF NEUROSCIENCE RESEARCH

PPISURV: a novel bioinformatics tool for uncovering the hidden role of specific genes in cancer survival outcome

(2013) A V Antonov et al.   ONCOGENE

Casein Kinase 1 Alpha Regulates Chromosome Congression and Separation during Mouse Oocyte Meiotic Maturation and Early Embryo Development

(2013) Lu Wang et al.   PLoS One

CK1δ Kinase Activity Is Modulated by Chk1-Mediated Phosphorylation

(2013) Joachim Bischof et al.   PLoS One

RNA Helicase DDX3 Is a Regulatory Subunit of Casein Kinase 1 in Wnt- -Catenin Signaling

(2013) C.-M. Cruciat et al.   SCIENCE

Pyrvinium targets autophagy addiction to promote cancer cell death

(2013) Longfei Deng et al.   Cell Death & Disease

MiR-155 Is a Liposarcoma Oncogene That Targets Casein Kinase-1  and Enhances  -Catenin Signaling

(2012) P. Zhang et al.   CANCER RESEARCH

Casein kinase I epsilon interacts with mitochondrial proteins for the growth and survival of human ovarian cancer cells

(2012) Noah Rodriguez et al.   EMBO Molecular Medicine

Casein Kinase 1  Regulates an MDMX Intramolecular Interaction To Stimulate p53 Binding

(2012) S. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Impaired CK1 Delta Activity Attenuates SV40-Induced Cellular Transformation In Vitro and Mouse Mammary Carcinogenesis In Vivo

(2012) Heidrun Hirner et al.   PLoS One

Functional genomics identifies therapeutic targets for MYC-driven cancer

(2012) M. Toyoshima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Sequential Activation and Inactivation of Dishevelled in the Wnt/β-Catenin Pathway by Casein Kinases

(2011) Ondrej Bernatik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a–dependent neurite outgrowth

(2011) Yoshimi Endo Greer et al.   JOURNAL OF CELL BIOLOGY

Differential expression patterns of capping protein, protein phosphatase 1, and casein kinase 1 may serve as diagnostic markers for malignant melanoma

(2011) Daxin Sun et al.   MELANOMA RESEARCH

Coordinated Action of CK1 Isoforms in Canonical Wnt Signaling

(2011) B. del Valle-Perez et al.   MOLECULAR AND CELLULAR BIOLOGY

mTOR Generates an Auto-Amplification Loop by Triggering the βTrCP- and CK1α-Dependent Degradation of DEPTOR

(2011) Shanshan Duan et al.   MOLECULAR CELL

CKIα ablation highlights a critical role for p53 in invasiveness control

(2011) Ela Elyada et al.   NATURE

IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation

(2011) J K Cheong et al.   ONCOGENE

Silymarin Targets β-Catenin Signaling in Blocking Migration/Invasion of Human Melanoma Cells

(2011) Mudit Vaid et al.   PLoS One

β-Catenin Signaling Increases during Melanoma Progression and Promotes Tumor Cell Survival and Chemoresistance

(2011) Tobias Sinnberg et al.   PLoS One

Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase

(2010) Hiroyuki Inuzuka et al.   CANCER CELL

Suppression of Casein Kinase 1  in Melanoma Cells Induces a Switch in  -Catenin Signaling to Promote Metastasis

(2010) T. Sinnberg et al.   CANCER RESEARCH

Casein kinase 1: Complexity in the family

(2010) Jit Kong Cheong et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

(2010) Curtis A Thorne et al.   Nature Chemical Biology

CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

(2010) So Young Kim et al.   PLoS One

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

(2010) Q.-J. Meng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Re-evaluation of the “Oncogenic” Nature of Wnt/β-catenin Signaling in Melanoma and Other Cancers

(2010) Olivia M. Lucero et al.   Current Oncology Reports

High-Throughput Chemical Screen Identifies a Novel Potent Modulator of Cellular Circadian Rhythms and Reveals CKIα as a Clock Regulatory Kinase

(2010) Tsuyoshi Hirota et al.   PLOS BIOLOGY

Isoform specific phosphorylation of p53 by protein kinase CK1

(2009) Andrea Venerando et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

CK1α Plays a Central Role in Mediating MDM2 Control of p53 and E2F-1 Protein Stability

(2009) Anne-Sophie Huart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophosphorylation of carboxy-terminal residues inhibits the activity of protein kinase CK1α

(2009) Mauricio Budini et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Selective Inhibition of Casein Kinase 1  Minimally Alters Circadian Clock Period

(2009) K. M. Walton et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Casein kinase 1α governs antigen-receptor-induced NF-κB activation and human lymphoma cell survival

(2009) Nicolas Bidère et al.   NATURE

Activated Wnt/ss-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model

(2009) A. J. Chien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo

(2008) C Brockschmidt et al.   GUT

Pyrvinium Targets the Unfolded Protein Response to Hypoglycemia and Its Anti-Tumor Activity Is Enhanced by Combination Therapy

(2008) De-Hua Yu et al.   PLoS One