Insights into the role of the beta-2 microglobulin D-strand in amyloid propensity revealed by mass spectrometry

Novel insights into protein misfolding diseases revealed by ion mobility-mass spectrometry

(2013) Danielle M. Williams et al.   MASS SPECTROMETRY REVIEWS

Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-  species

(2013) S.-J. Hyung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Familial Alzheimer’s Disease Mutations Differentially Alter Amyloid β-Protein Oligomerization

(2012) Megan Murray Gessel et al.   ACS Chemical Neuroscience

A recurrent D-strand association interface is observed in β-2 microglobulin oligomers

(2012) Matteo Colombo et al.   FEBS Journal

Out-of-register  -sheets suggest a pathway to toxic amyloid aggregates

(2012) C. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Insights into the Pre-Amyloid Tetramer of β-2-Microglobulin from Covalent Labeling and Mass Spectrometry

(2011) Vanessa Leah Mendoza et al.   BIOCHEMISTRY

Structure and Dynamics of Oligomeric Intermediates in β2-Microglobulin Self-Assembly

(2011) David P. Smith et al.   BIOPHYSICAL JOURNAL

D-strand perturbation and amyloid propensity in beta-2 microglobulin

(2011) Stavros Azinas et al.   FEBS Journal

Understanding the complex mechanisms of β2-microglobulin amyloid assembly

(2011) Timo Eichner et al.   FEBS Journal

A Diversity of Assembly Mechanisms of a Generic Amyloid Fold

(2011) Timo Eichner et al.   MOLECULAR CELL

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein

(2011) Lucy A Woods et al.   Nature Chemical Biology

In vivo demonstration that  -synuclein oligomers are toxic

(2011) B. Winner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Preamyloid Dimer of β-2-Microglobulin from Covalent Labeling and Mass Spectrometry

(2010) Vanessa Leah Mendoza et al.   BIOCHEMISTRY

Stacked Sets of Parallel, In-register β-Strands of β2-Microglobulin in Amyloid Fibrils Revealed by Site-directed Spin Labeling and Chemical Labeling

(2010) Carol L. Ladner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intermolecular Alignment in β2-Microglobulin Amyloid Fibrils

(2010) Galia T. Debelouchina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mass spectrometry and the amyloid problem—How far can we go in the gas phase?

(2010) Alison E. Ashcroft   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Metal binding sheds light on mechanisms of amyloid assembly

(2010) Matthew F. Calabrese et al.   Prion

Elongated oligomers in  2-microglobulin amyloid assembly revealed by ion mobility spectrometry-mass spectrometry

(2010) D. P. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DE-loop mutations affect β2 microglobulin stability, oligomerization, and the low-pH unfolded form

(2010) Carlo Santambrogio et al.   PROTEIN SCIENCE

Globular Tetramers of β2-Microglobulin Assemble into Elaborate Amyloid Fibrils

(2009) Helen E. White et al.   JOURNAL OF MOLECULAR BIOLOGY

A Generic Mechanism of β2-Microglobulin Amyloid Assembly at Neutral pH Involving a Specific Proline Switch

(2009) Timo Eichner et al.   JOURNAL OF MOLECULAR BIOLOGY

Competition between Intramolecular and Intermolecular Interactions in an Amyloid-Forming Protein

(2009) Katy E. Routledge et al.   JOURNAL OF MOLECULAR BIOLOGY

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

(2009) Jennifer L. Tomic et al.   NEUROBIOLOGY OF DISEASE

DE loop mutations affect β2-microglobulin stability and amyloid aggregation

(2008) Stefano Ricagno et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Controlling Roles of Trp60 and Trp95 in β2-Microglobulin Function, Folding and Amyloid Aggregation Properties

(2008) Gennaro Esposito et al.   JOURNAL OF MOLECULAR BIOLOGY

Fibril Growth Kinetics Reveal a Region of β2-microglobulin Important for Nucleation and Elongation of Aggregation

(2008) Geoffrey W. Platt et al.   JOURNAL OF MOLECULAR BIOLOGY

HDX-ESI-MS reveals enhanced conformational dynamics of the amyloidogenic protein β 2-microglobulin upon release from the MHC-1

(2008) John P. Hodkinson et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

(2008) Dagmar E Ehrnhoefer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The solution structure of human β2-microglobulin reveals the prodromes of its amyloid transition

(2002) Giuliana Verdone et al.   PROTEIN SCIENCE