Novel insights into protein misfolding diseases revealed by ion mobility-mass spectrometry

Z-Phe-Ala-diazomethylketone (PADK) Disrupts and Remodels Early Oligomer States of the Alzheimer Disease Aβ42 Protein

(2012) Xueyun Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Traveling-wave ion mobility mass spectrometry of protein complexes: accurate calibrated collision cross-sections of human insulin oligomers

(2012) Rune Salbo et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Advances in the Mass Spectrometry of Membrane Proteins: From Individual Proteins to Intact Complexes

(2011) Nelson P. Barrera et al.   Annual Review of Biochemistry

Ion Mobility Mass Spectrometry Studies of the Inhibition of Alpha Synuclein Amyloid Fibril Formation by (–)-Epigallocatechin-3-Gallate

(2011) Yanqin Liu et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Aβ(39–42) Modulates Aβ Oligomerization but Not Fibril Formation

(2011) Megan Murray Gessel et al.   BIOCHEMISTRY

Autoproteolytic Fragments Are Intermediates in the Oligomerization/Aggregation of the Parkinson's Disease Protein Alpha-Synuclein as Revealed by Ion Mobility Mass Spectrometry

(2011) Camelia Vlad et al.   CHEMBIOCHEM

Unravelling the twists and turns of the serpinopathies

(2011) Benoit D. Roussel et al.   FEBS Journal

Ion Mobility Separation Coupled with MS Detects Two Structural States of Alzheimer's Disease Aβ1–40 Peptide Oligomers

(2011) Marcin Kłoniecki et al.   JOURNAL OF MOLECULAR BIOLOGY

The Amyloid Formation Mechanism in Human IAPP: Dimers Have β-Strand Monomer−Monomer Interfaces

(2011) Nicholas F. Dupuis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein

(2011) Lucy A Woods et al.   Nature Chemical Biology

APP processing in Alzheimer's disease

(2011) Yun-wu Zhang et al.   Molecular Brain

Collision Cross Sections of Proteins and Their Complexes: A Calibration Framework and Database for Gas-Phase Structural Biology

(2010) Matthew F. Bush et al.   ANALYTICAL CHEMISTRY

Protein aggregation—Pathways and influencing factors

(2010) Wei Wang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Conformational Stability of Syrian Hamster Prion Protein PrP(90−231)

(2010) Megan Grabenauer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural analysis of prion proteins by means of drift cell and traveling wave ion mobility mass spectrometry

(2010) Gillian R. Hilton et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Current limitations in native mass spectrometry based structural biology

(2010) Esther Duijn   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Integrating Ion Mobility Mass Spectrometry with Molecular Modelling to Determine the Architecture of Multiprotein Complexes

(2010) Argyris Politis et al.   PLoS One

Elongated oligomers in  2-microglobulin amyloid assembly revealed by ion mobility spectrometry-mass spectrometry

(2010) D. P. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defining the mechanism of polymerization in the serpinopathies

(2010) U. I. Ekeowa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

(2009) Liping Yu et al.   BIOCHEMISTRY

Determination of the Oligomer Size of Amyloidogenic Protein β-Amyloid(1–40) by Single-Molecule Spectroscopy

(2009) Hao Ding et al.   BIOPHYSICAL JOURNAL

Ion mobility mass spectrometry of proteins and proteinassemblies

(2009) Charlotte Uetrecht et al.   CHEMICAL SOCIETY REVIEWS

Gas-Phase Unfolding and Disassembly Reveals Stability Differences in Ligand-Bound Multiprotein Complexes

(2009) Suk-Joon Hyung et al.   CHEMISTRY & BIOLOGY

Evolutionary changes to transthyretin: structure-function relationships

(2009) P. Prapunpoj et al.   FEBS Journal

Gas-phase metalloprotein complexes interrogated by ion mobility-mass spectrometry

(2009) Peter A. Faull et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Residual counter ions can stabilise a large protein complex in the gas phase

(2009) Joanna Freeke et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

The Effect of Calcium Ions and Peptide Ligands on the Relative Stabilities of the Calmodulin Dumbbell and Compact Structures

(2009) Thomas Wyttenbach et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Chaperonin Complexes Monitored by Ion Mobility Mass Spectrometry

(2009) Esther van Duijn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amyloid β Protein: Aβ40 Inhibits Aβ42 Oligomerization

(2009) Megan M. Murray et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Human Islet Amyloid Polypeptide Monomers Form Ordered β-hairpins: A Possible Direct Amyloidogenic Precursor

(2009) Nicholas F. Dupuis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Methodology for measuring conformation of solvent-disrupted protein subunits using T-WAVE ion mobility MS: An investigation into eukaryotic initiation factors

(2009) Julie A. Leary et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

(2009) Summer L. Bernstein et al.   Nature Chemistry

Subunit Architecture of Multiprotein Assemblies Determined Using Restraints from Gas-Phase Measurements

(2009) Tara L. Pukala et al.   STRUCTURE

Monitoring the earliest amyloid-β oligomers via quantized photobleaching of dye-labeled peptides

(2008) Kyle D. Dukes et al.   ANALYTICAL BIOCHEMISTRY

Fundamentals of Traveling Wave Ion Mobility Spectrometry

(2008) Alexandre A. Shvartsburg et al.   ANALYTICAL CHEMISTRY

Characterization of Phosphorylated Peptides Using Traveling Wave-Based and Drift Cell Ion Mobility Mass Spectrometry

(2008) Konstantinos Thalassinos et al.   ANALYTICAL CHEMISTRY

Stability and Shape of Hepatitis B Virus Capsids In Vacuo

(2008) Charlotte Uetrecht et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biomolecule Analysis by Ion Mobility Spectrometry

(2008) Brian C. Bohrer et al.   Annual Review of Analytical Chemistry

Molecular mechanisms of α-synuclein neurodegeneration

(2008) Elisa A. Waxman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Unraveling the mysteries of protein folding and misfolding

(2008) Heath Ecroyd et al.   IUBMB LIFE

The Ratio of Monomeric to Aggregated Forms of Aβ40 and Aβ42 Is an Important Determinant of Amyloid-β Aggregation, Fibrillogenesis, and Toxicity

(2008) Asad Jan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spermine Binding to Parkinson’s Protein α-Synuclein and Its Disease-Related A30P and A53T Mutants

(2008) Megan Grabenauer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization

(2008) Masayuki Yamasaki et al.   NATURE

Ion mobility–mass spectrometry analysis of large protein complexes

(2008) Brandon T Ruotolo et al.   Nature Protocols

GroEL stimulates protein folding through forced unfolding

(2008) Zong Lin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Travelling wave ion mobility mass spectrometry studies of protein structure: biological significance and comparison with X-ray crystallography and nuclear magnetic resonance spectroscopy measurements

(2008) Charlotte A. Scarff et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY