Out-of-register  -sheets suggest a pathway to toxic amyloid aggregates

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

(2012) Nunilo Cremades et al.   CELL

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

Microcin Amyloid Fibrils A Are Reservoir of Toxic Oligomeric Species

(2012) Mohammad Shahnawaz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Amyloid Formation

(2012) Torleif Härd et al.   JOURNAL OF MOLECULAR BIOLOGY

Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity

(2012) Pin-Nan Cheng et al.   Nature Chemistry

Antiparallel  -sheet architecture in Iowa-mutant  -amyloid fibrils

(2012) W. Qiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxic fibrillar oligomers of amyloid-  have cross-  structure

(2012) J. C. Stroud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic View of a Toxic Amyloid Small Oligomer

(2012) Arthur Laganowsky et al.   SCIENCE

Amyloid Structure: Conformational Diversity and Consequences

(2011) Brandon H. Toyama et al.   Annual Review of Biochemistry

Solid-State NMR Studies of Amyloid Fibril Structure

(2011) Robert Tycko   Annual Review of Physical Chemistry

Understanding the complex mechanisms of β2-microglobulin amyloid assembly

(2011) Timo Eichner et al.   FEBS Journal

In Vivo and In Vitro Analyses of Toxic Mutants of HET-s: FTIR Antiparallel Signature Correlates with Amyloid Toxicity

(2011) Karine Berthelot et al.   JOURNAL OF MOLECULAR BIOLOGY

Selective Molecular Recognition in Amyloid Growth and Transmission and Cross-Species Barriers

(2011) Buyong Ma et al.   JOURNAL OF MOLECULAR BIOLOGY

Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic β-Sheet Mimics

(2011) Cong Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Diversity of Assembly Mechanisms of a Generic Amyloid Fold

(2011) Timo Eichner et al.   MOLECULAR CELL

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Principles governing oligomer formation in amyloidogenic peptides

(2010) John E Straub et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Low molecular weight oligomers of amyloid peptides display β-barrel conformations: A replica exchange molecular dynamics study in explicit solvent

(2010) Alfonso De Simone et al.   JOURNAL OF CHEMICAL PHYSICS

β-Barrel Topology of Alzheimer's β-Amyloid Ion Channels

(2010) Hyunbum Jang et al.   JOURNAL OF MOLECULAR BIOLOGY

A causative link between the structure of aberrant protein oligomers and their toxicity

(2010) Silvia Campioni et al.   Nature Chemical Biology

β2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages

(2010) Cong Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils

(2010) Mahiuddin Ahmed et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Interplay of Catalysis and Toxicity by Amyloid Intermediates on Lipid Bilayers: Insights from Type II Diabetes

(2009) James A. Hebda et al.   Annual Review of Biophysics

Antiparallel β-sheet: a signature structure of the oligomeric amyloid β-peptide

(2009) Emilie Cerf et al.   BIOCHEMICAL JOURNAL

β arcades: recurring motifs in naturally occurring and disease-related amyloid fibrils

(2009) Andrey V. Kajava et al.   FASEB JOURNAL

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibril Growth Kinetics Reveal a Region of β2-microglobulin Important for Nucleation and Elongation of Aggregation

(2008) Geoffrey W. Platt et al.   JOURNAL OF MOLECULAR BIOLOGY

The fold of  -synuclein fibrils

(2008) M. Vilar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibrils with parallel in-register structure constitute a major class of amyloid fibrils: molecular insights from electron paramagnetic resonance spectroscopy

(2008) Martin Margittai et al.   QUARTERLY REVIEWS OF BIOPHYSICS