Building synthetic gene circuits from combinatorial libraries: screening and selection strategies

Synthetic Biology: An Emerging Engineering Discipline

(2012) Allen A. Cheng et al.   Annual Review of Biomedical Engineering

Contextualizing context for synthetic biology - identifying causes of failure of synthetic biological systems

(2012) Stefano Cardinale et al.   Biotechnology Journal

A Synthetic Biology Framework for Programming Eukaryotic Transcription Functions

(2012) Ahmad S. Khalil et al.   CELL

Expanding the synthetic biology toolbox: engineering orthogonal regulators of gene expression

(2012) Christopher V Rao   CURRENT OPINION IN BIOTECHNOLOGY

Engineering multicellular traits in synthetic microbial populations

(2012) John S Chuang   CURRENT OPINION IN CHEMICAL BIOLOGY

Microfluidic technologies for studying synthetic circuits

(2012) Benjamin Lin et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Computational methods in synthetic biology: towards computer-aided part design

(2012) Kang Wu et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Successes and failures in modular genetic engineering

(2012) Joshua T Kittleson et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Synthetic biology advancing clinical applications

(2012) Marc Folcher et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Directed evolution: an evolving and enabling synthetic biology tool

(2012) Ryan E Cobb et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Perspectives on the automatic design of regulatory systems for synthetic biology

(2012) Guillermo Rodrigo et al.   FEBS LETTERS

Directed evolution as a powerful synthetic biology tool

(2012) Ryan E. Cobb et al.   METHODS

Genetic programs constructed from layered logic gates in single cells

(2012) Tae Seok Moon et al.   NATURE

Iterative plug-and-play methodology for constructing and modifying synthetic gene networks

(2012) Kevin D Litcofsky et al.   NATURE METHODS

Foundations for the design and implementation of synthetic genetic circuits

(2012) Adrian L. Slusarczyk et al.   NATURE REVIEWS GENETICS

Modular control of multiple pathways using engineered orthogonal T7 polymerases

(2012) Karsten Temme et al.   NUCLEIC ACIDS RESEARCH

Rational Diversification of a Promoter Providing Fine-Tuned Expression and Orthogonal Regulation for Synthetic Biology

(2012) Benjamin A. Blount et al.   PLoS One

The PLOS ONE Synthetic Biology Collection: Six Years and Counting

(2012) Jean Peccoud et al.   PLoS One

Fine-tuning gene networks using simple sequence repeats

(2012) R. G. Egbert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rewritable digital data storage in live cells via engineered control of recombination directionality

(2012) J. Bonnet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Genetic Polymers Capable of Heredity and Evolution

(2012) V. B. Pinheiro et al.   SCIENCE

Understanding Signaling Dynamics Through Synthesis

(2012) A. L. Slusarczyk et al.   Science Signaling

High-content screening in infectious diseases

(2011) Priscille Brodin et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

DNA assembly for synthetic biology: from parts to pathways and beyond

(2011) Tom Ellis et al.   Integrative Biology

Develop reusable and combinable designs for transcriptional logic gates

(2011) Jian Zhan et al.   Molecular Systems Biology

A sensing array of radically coupled genetic ‘biopixels’

(2011) Arthur Prindle et al.   NATURE

Self-reproduction of supramolecular giant vesicles combined with the amplification of encapsulated DNA

(2011) Kensuke Kurihara et al.   Nature Chemistry

Computational design of synthetic regulatory networks from a genetic library to characterize the designability of dynamical behaviors

(2011) Guillermo Rodrigo et al.   NUCLEIC ACIDS RESEARCH

Model-Driven Engineering of RNA Devices to Quantitatively Program Gene Expression

(2011) J. M. Carothers et al.   SCIENCE

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

(2011) S. J. Fleishman et al.   SCIENCE

The beautiful cell: high-content screening in drug discovery

(2010) Marc Bickle   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Synthesizing a novel genetic sequential logic circuit: a push-on push-off switch

(2010) Chunbo Lou et al.   Molecular Systems Biology

Distributed biological computation with multicellular engineered networks

(2010) Sergi Regot et al.   NATURE

Robust multicellular computing using genetically encoded NOR gates and chemical ‘wires’

(2010) Alvin Tamsir et al.   NATURE

Five hard truths for synthetic biology

(2010) Roberta Kwok   NATURE

A nucleoside kinase as a dual selector for genetic switches and circuits

(2010) Yohei Tashiro et al.   NUCLEIC ACIDS RESEARCH

Oscillations by Minimal Bacterial Suicide Circuits Reveal Hidden Facets of Host-Circuit Physiology

(2010) Philippe Marguet et al.   PLoS One

Synthetic design of strong promoters

(2010) M. R. Schlabach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

(2010) D. G. Gibson et al.   SCIENCE

High content screening: seeing is believing

(2010) Fabian Zanella et al.   TRENDS IN BIOTECHNOLOGY

Mechanism-Guided Library Design and Dual Genetic Selection of Synthetic OFF Riboswitches

(2009) Norihito Muranaka et al.   CHEMBIOCHEM

Engineering of Synthetic Mammalian Gene Networks

(2009) Wilfried Weber et al.   CHEMISTRY & BIOLOGY

Directed evolution: new parts and optimized function

(2009) Michael J Dougherty et al.   CURRENT OPINION IN BIOTECHNOLOGY

A Novel Molecular Switch

(2009) Robert Daber et al.   JOURNAL OF MOLECULAR BIOLOGY

Opportunities for microfluidic technologies in synthetic biology

(2009) S. Gulati et al.   Journal of the Royal Society Interface

The potential of microfluidic water-in-oil droplets in experimental biology

(2009) Yolanda Schaerli et al.   Molecular BioSystems

Programming cells by multiplex genome engineering and accelerated evolution

(2009) Harris H. Wang et al.   NATURE

Diversity-based, model-guided construction of synthetic gene networks with predicted functions

(2009) Tom Ellis et al.   NATURE BIOTECHNOLOGY

Automated design of synthetic ribosome binding sites to control protein expression

(2009) Howard M Salis et al.   NATURE BIOTECHNOLOGY

Emergent bistability by a growth-modulating positive feedback circuit

(2009) Cheemeng Tan et al.   Nature Chemical Biology

An efficient platform for genetic selection and screening of gene switches in Escherichia coli

(2009) Norihito Muranaka et al.   NUCLEIC ACIDS RESEARCH

High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli

(2009) Hiroko Tsuruta et al.   PLoS One

Design Parameters to Control Synthetic Gene Expression in Escherichia coli

(2009) Mark Welch et al.   PLoS One

Synthesis of orthogonal transcription-translation networks

(2009) W. An et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coding-Sequence Determinants of Gene Expression in Escherichia coli

(2009) G. Kudla et al.   SCIENCE

Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels

(2008) Sung Kuk Lee et al.   CURRENT OPINION IN BIOTECHNOLOGY

Refinement and standardization of synthetic biological parts and devices

(2008) Barry Canton et al.   NATURE BIOTECHNOLOGY