CEBPA exerts a specific and biologically important proapoptotic role in pancreatic β cells through its downstream network targets

LASAGNA: A novel algorithm for transcription factor binding site alignment

(2013) Chih Lee et al.   BMC BIOINFORMATICS

miR-296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to β cells

(2013) Davide Barbagallo et al.   BMC GENOMICS

Sox4 Is a Key Oncogenic Target in C/EBPα Mutant Acute Myeloid Leukemia

(2013) Hong Zhang et al.   CANCER CELL

Epigenomic plasticity enables human pancreatic α to β cell reprogramming

(2013) Nuria C. Bramswig et al.   JOURNAL OF CLINICAL INVESTIGATION

Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases

(2013) Younghee Lee et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Transcription Factors That Convert Adult Cell Identity Are Differentially Polycomb Repressed

(2013) Fred P. Davis et al.   PLoS One

Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity

(2013) Ashleigh E. Schaffer et al.   PLoS Genetics

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells

(2012) F Allagnat et al.   CELL DEATH AND DIFFERENTIATION

Divalent Metal Transporter 1 Regulates Iron-Mediated ROS and Pancreatic β Cell Fate in Response to Cytokines

(2012) Jakob Bondo Hansen et al.   Cell Metabolism

Imaging of β-Cell Mass and Insulitis in Insulin-Dependent (Type 1) Diabetes Mellitus

(2012) Valentina Di Gialleonardo et al.   ENDOCRINE REVIEWS

Specific alterations of the microRNA transcriptome and global network structure in colorectal cancer after treatment with MAPK/ERK inhibitors

(2012) Marco Ragusa et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Post-transcriptional modulation of C/EBPα prompts monocytic differentiation and apoptosis in acute myelomonocytic leukaemia cells

(2012) Hideki Yoshida et al.   LEUKEMIA RESEARCH

The Transcription Factor C/EBP delta Has Anti-Apoptotic and Anti-Inflammatory Roles in Pancreatic Beta Cells

(2012) Fabrice Moore et al.   PLoS One

The CCAAT/enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation

(2011) Junichi Tsukada et al.   CYTOKINE

The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse

(2011) J. T. Eppig et al.   NUCLEIC ACIDS RESEARCH

AnimalTFDB: a comprehensive animal transcription factor database

(2011) H.-M. Zhang et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Profiling of H3K56 Acetylation and Transcription Factor Binding Sites in Human Adipocytes

(2011) Kinyui Alice Lo et al.   PLoS One

C/EBP  regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations

(2010) J. A. Pulikkan et al.   BLOOD

The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML

(2010) M Eyholzer et al.   BRITISH JOURNAL OF CANCER

Praf2 Is a Novel Bcl-xL/Bcl-2 Interacting Protein with the Ability to Modulate Survival of Cancer Cells

(2010) Maria Teresa Vento et al.   PLoS One

Over-expression of C/EBP-α induces apoptosis in cultured rat hepatic stellate cells depending on p53 and peroxisome proliferator-activated receptor-γ

(2009) Xueqing Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma

(2009) Cinzia Di Pietro et al.   BMC Medical Genomics

Cytokines Interleukin-1  and Tumor Necrosis Factor-  Regulate Different Transcriptional and Alternative Splicing Networks in Primary  -Cells

(2009) F. Ortis et al.   DIABETES

Cytokine-mediated induction of anti-apoptotic genes that are linked to nuclear factor kappa-B (NF-κB) signalling in human islets and in a mouse beta cell line

(2009) S. A. Sarkar et al.   DIABETOLOGIA

NF- B p50 Regulates C/EBP  Expression and Inflammatory Cytokine-Induced Neutrophil Production

(2009) D. Wang et al.   JOURNAL OF IMMUNOLOGY

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Cytokines and β-Cell Biology: from Concept to Clinical Translation

(2008) Marc Y. Donath et al.   ENDOCRINE REVIEWS

Regulation of apoptotic and growth inhibitory activities of C/EBPα in different cell lines

(2008) Guo-Li Wang et al.   EXPERIMENTAL CELL RESEARCH

Hubba: hub objects analyzer—a framework of interactome hubs identification for network biology

(2008) Chung-Yen Lin et al.   NUCLEIC ACIDS RESEARCH

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH