A Model of Substitution Trajectories in Sequence Space and Long-Term Protein Evolution

Empirical fitness landscapes and the predictability of evolution

(2014) J. Arjan G.M. de Visser et al.   NATURE REVIEWS GENETICS

The inherent mutational tolerance and antigenic evolvability of influenza hemagglutinin

(2014) Bargavi Thyagarajan et al.   eLife

WHY EPISTASIS IS IMPORTANT FOR SELECTION AND ADAPTATION

(2013) Thomas F. Hansen   EVOLUTION

Analyses of the Effects of All Ubiquitin Point Mutants on Yeast Growth Rate

(2013) Benjamin P. Roscoe et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantifying the similarity of monotonic trajectories in rough and smooth fitness landscapes

(2013) Alexander E. Lobkovsky et al.   Molecular BioSystems

Breen et al. reply

(2013) Michael S. Breen et al.   NATURE

The role of epistasis in protein evolution

(2013) David M. McCandlish et al.   NATURE

Emerging methods in protein co-evolution

(2013) David de Juan et al.   NATURE REVIEWS GENETICS

Experiments on the role of deleterious mutations as stepping stones in adaptive evolution

(2013) Arthur W. Covert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Protein Sequence Divergence and Incompatibility

(2013) Alon Wellner et al.   PLoS Genetics

Stability-mediated epistasis constrains the evolution of an influenza protein

(2013) Lizhi Ian Gong et al.   eLife

Evolutionary Inferences from Phylogenies: A Review of Methods

(2012) Brian C. O'Meara   Annual Review of Ecology Evolution and Systematics

Multidimensional epistasis and fitness landscapes in enzyme evolution

(2012) Wei Zhang et al.   BIOCHEMICAL JOURNAL

Fitness conferred by replaced amino acids declines with time

(2012) S. A. Naumenko et al.   Biology Letters

Estimating the Rate of Irreversibility in Protein Evolution

(2012) Onuralp Soylemez et al.   Genome Biology and Evolution

The peaks and geometry of fitness landscapes

(2012) Kristina Crona et al.   JOURNAL OF THEORETICAL BIOLOGY

The spatial architecture of protein function and adaptation

(2012) Richard N. McLaughlin Jr et al.   NATURE

Epistasis as the primary factor in molecular evolution

(2012) Michael S. Breen et al.   NATURE

The causes of epistasis

(2011) J. A. G. M. de Visser et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Negative Epistasis Between Beneficial Mutations in an Evolving Bacterial Population

(2011) A. I. Khan et al.   SCIENCE

Molecular mechanisms of epistasis within and between genes

(2011) Ben Lehner   TRENDS IN GENETICS

Rate of sequence divergence under constant selection

(2010) Alexey S Kondrashov et al.   Biology Direct

Functionally Compensating Coevolving Positions Are Neither Homoplasic Nor Conserved in Clades

(2010) G. B. Gloor et al.   MOLECULAR BIOLOGY AND EVOLUTION

Sequence space and the ongoing expansion of the protein universe

(2010) Inna S. Povolotskaya et al.   NATURE

Evolutionary Innovations and the Organization of Protein Functions in Genotype Space

(2010) Evandro Ferrada et al.   PLoS One

Pervasive Cryptic Epistasis in Molecular Evolution

(2010) Mark Lunzer et al.   PLoS Genetics

An epistatic ratchet constrains the direction of glucocorticoid receptor evolution

(2009) Jamie T. Bridgham et al.   NATURE

Exploring protein fitness landscapes by directed evolution

(2009) Philip A. Romero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stepwise acquisition of pyrimethamine resistance in the malaria parasite

(2009) E. R. Lozovsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Homoplasy in genome-wide analysis of rare amino acid replacements: the molecular-evolutionary basis for Vavilov's law of homologous series

(2008) Igor B Rogozin et al.   Biology Direct

Parallel Genetic Evolution Within and Between Bacteriophage Species of Varying Degrees of Divergence

(2008) J. P. Bollback et al.   GENETICS

Frequent and Widespread Parallel Evolution of Protein Sequences

(2008) A. Rokas et al.   MOLECULAR BIOLOGY AND EVOLUTION