Endoplasmic reticulum aminopeptidase 2 haplotypes play a role in modulating susceptibility to HIV infection

A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen Processing

(2012) I. Evnouchidou et al.   JOURNAL OF IMMUNOLOGY

A Functional Variant in ERAP1 Predisposes to Multiple Sclerosis

(2012) Franca Rosa Guerini et al.   PLoS One

Common HIV-1 Peptide Variants Mediate Differential Binding of KIR3DL1 to HLA-Bw4 Molecules

(2011) L. Fadda et al.   JOURNAL OF VIROLOGY

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

Human cytomegalovirus microRNA miR-US4-1 inhibits CD8+ T cell responses by targeting the aminopeptidase ERAP1

(2011) Sungchul Kim et al.   NATURE IMMUNOLOGY

Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection

(2010) R. Cagliani et al.   HUMAN MOLECULAR GENETICS

Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Defines the Composition and Structure of MHC Class I Peptide Repertoire in Normal and Virus-Infected Cells

(2010) N. Blanchard et al.   JOURNAL OF IMMUNOLOGY

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

(2010) Amy Strange et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Endoplasmic reticulum aminopeptidases: biology and pathogenic potential

(2010) Nigil Haroon et al.   Nature Reviews Rheumatology

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

(2010)   SCIENCE

Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation

(2010) Aida M. Andrés et al.   PLoS Genetics

Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis

(2009) F. W. L. Tsui et al.   ANNALS OF THE RHEUMATIC DISEASES

The peptide-loading complex – antigen translocation and MHC class I loading

(2009) Christian Schölz et al.   BIOLOGICAL CHEMISTRY

Fine-Scale Variation and Genetic Determinants of Alternative Splicing across Individuals

(2009) Jasmin Coulombe-Huntington et al.   PLoS Genetics

Vitamin D Receptor Gene Haplotypes and Susceptibility to HIV‐1 Infection in Injection Drug Users

(2008) Manuel Sánchez de la Torre et al.   JOURNAL OF INFECTIOUS DISEASES