Reproduction and Immunity-Driven Natural Selection in the Human WFDC Locus

The Major Bactericidal Activity of Human Seminal Plasma Is Zinc-Dependent and Derived from Fragmentation of the Semenogelins

(2014) A. M. L. Edstrom et al.   JOURNAL OF IMMUNOLOGY

Genes encoding WFDC- and Kunitz-type protease inhibitor domains: are they related?

(2012) Åke Lundwall et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

SLPI and inflammatory lung disease in females

(2012) Paul J. McKiernan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Loss and Gain of Function in SERPINB11: An Example of a Gene under Selection on Standing Variation, with Implications for Host-Pathogen Interactions

(2012) Susana Seixas et al.   PLoS One

Three genes expressing Kunitz domains in the epididymis are related to genes of WFDC-type protease inhibitors and semen coagulum proteins in spite of lacking similarity between their protein products

(2011) Adam Clauss et al.   BMC BIOCHEMISTRY

Differing Evolutionary Histories of WFDC8 (Short-Term Balancing) in Europeans and SPINT4 (Incomplete Selective Sweep) in Africans

(2011) Z. Ferreira et al.   MOLECULAR BIOLOGY AND EVOLUTION

Evolution of the TIR Domain-Containing Adaptors in Humans: Swinging between Constraint and Adaptation

(2011) Simona Fornarino et al.   MOLECULAR BIOLOGY AND EVOLUTION

Identification and characterization of Wfdc gene expression in the male reproductive tract of the rat

(2011) Angireddy Rajesh et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Classic Selective Sweeps Were Rare in Recent Human Evolution

(2011) R. D. Hernandez et al.   SCIENCE

Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution

(2011) Matteo Fumagalli et al.   PLoS Genetics

The Genetics of Human Adaptation: Hard Sweeps, Soft Sweeps, and Polygenic Adaptation

(2010) Jonathan K. Pritchard et al.   CURRENT BIOLOGY

Effect of Experimental Diabetes and STZ on Male Fertility Capacity. Study in Rats

(2010) L. Navarro-Casado et al.   JOURNAL OF ANDROLOGY

Population Genetic Analysis of the Uncoupling Proteins Supports a Role for UCP3 in Human Cold Resistance

(2010) A. M. Hancock et al.   MOLECULAR BIOLOGY AND EVOLUTION

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation

(2010) Aida M. Andrés et al.   PLoS Genetics

Cationic polypeptides contribute to the anti-HIV-1 activity of human seminal plasma

(2009) Julie A. Martellini et al.   FASEB JOURNAL

Darwinian and demographic forces affecting human protein coding genes

(2009) R. Nielsen et al.   GENOME RESEARCH

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays

(2009) R. Drmanac et al.   SCIENCE

Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

(2009) Luis B. Barreiro et al.   PLoS Genetics

Inferring the Joint Demographic History of Multiple Populations from Multidimensional SNP Frequency Data

(2009) Ryan N. Gutenkunst et al.   PLoS Genetics

The Role of Geography in Human Adaptation

(2009) Graham Coop et al.   PLoS Genetics

Hominoid seminal protein evolution and ancestral mating behavior

(2008) Sarah J. Carnahan et al.   AMERICAN JOURNAL OF PRIMATOLOGY

Effects of Vasectomy on Gene Expression Profiling along the Human Epididymis1

(2008) Véronique Thimon et al.   BIOLOGY OF REPRODUCTION

Widespread balancing selection and pathogen-driven selection at blood group antigen genes

(2008) M. Fumagalli et al.   GENOME RESEARCH

Natural selection has driven population differentiation in modern humans

(2008) Luis B Barreiro et al.   NATURE GENETICS

Identification of novel semenogelin I-derived antimicrobial peptide from liquefied human seminal plasma

(2008) Hui Zhao et al.   PEPTIDES

Novel innate immune functions of the whey acidic protein family

(2008) Colin D Bingle et al.   TRENDS IN IMMUNOLOGY