Therapeutic siRNAs and nonviral systems for their delivery

Advances in systemic siRNA delivery

(2015) Q. Leng et al.   DRUGS OF THE FUTURE

Sequencing of the 5′ region of the Lngfr gene associated with stress-induced arterial hypertension in ISIAH rats

(2011) L. A. Fedoseeva et al.   MOLECULAR BIOLOGY

Nanoparticle-Based Delivery System for Application of siRNA In Vivo

(2010) Yan Wang et al.   CURRENT DRUG METABOLISM

Efficient and targeted delivery of siRNA in vivo

(2010) Min Suk Shim et al.   FEBS Journal

Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo

(2010) Maria B. Laursen et al.   Molecular BioSystems

Rational Design of Immunostimulatory siRNAs

(2010) Michael P Gantier et al.   MOLECULAR THERAPY

In vivo electroporation of the central nervous system: A non-viral approach for targeted gene delivery

(2010) Jochen De Vry et al.   PROGRESS IN NEUROBIOLOGY

siRNA applications in nanomedicine

(2010) Talar Tokatlian et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Lipidic Systems for In Vivo siRNA Delivery

(2009) Sherry Y. Wu et al.   AAPS Journal

Systemic Therapeutic Gene Delivery for Cancer: Crafting Paris Arrow

(2009) Alex Tong et al.   CURRENT GENE THERAPY

Therapeutic silencing of an endogenous gene by siRNA cream in an arthritis model mouse

(2009) M Takanashi et al.   GENE THERAPY

Hyaluronic acid complexed to biodegradable poly L-arginine for targeted delivery of siRNAs

(2009) Eun-Joong Kim et al.   JOURNAL OF GENE MEDICINE

Novel Cationic Lipid That Delivers siRNA and Enhances Therapeutic Effect in Lung Cancer Cells

(2009) Yunching Chen et al.   MOLECULAR PHARMACEUTICS

Target Specific Intracellular Delivery of siRNA/PEI−HA Complex by Receptor Mediated Endocytosis

(2009) Ge Jiang et al.   MOLECULAR PHARMACEUTICS

Biological Barriers to Therapy with Antisense and siRNA Oligonucleotides

(2009) R. Juliano et al.   MOLECULAR PHARMACEUTICS

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

(2009) Justin P Dassie et al.   NATURE BIOTECHNOLOGY

Efficient siRNA delivery into primary cells by a peptide transduction domain–dsRNA binding domain fusion protein

(2009) Akiko Eguchi et al.   NATURE BIOTECHNOLOGY

siRNA and Innate Immunity

(2009) Marjorie Robbins et al.   OLIGONUCLEOTIDES

Non-viral nanosystems for systemic siRNA delivery

(2009) Stephanie David et al.   PHARMACOLOGICAL RESEARCH

Enhanced Cell Penetration of Acid-Degradable Particles Functionalized with Cell-Penetrating Peptides

(2008) Jessica L. Cohen et al.   BIOCONJUGATE CHEMISTRY

Silencing HIV-1 In Vivo

(2008) Frank Kirchhoff   CELL

Polymer nanocarriers for the delivery of small fragments of nucleic acids: Oligonucleotides and siRNA

(2008) H. de Martimprey et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol

(2008) Kazutaka Nishina et al.   MOLECULAR THERAPY

Thousands of proteins affected by miRNAs

(2008) Erika Check Hayden   NATURE

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

(2008) Hendrik Poeck et al.   NATURE MEDICINE

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides

(2008) R. Juliano et al.   NUCLEIC ACIDS RESEARCH

Chemical Modification of siRNAs for In Vivo Use

(2008) Mark A. Behlke   OLIGONUCLEOTIDES

Systemic Leukocyte-Directed siRNA Delivery Revealing Cyclin D1 as an Anti-Inflammatory Target

(2008) D. Peer et al.   SCIENCE

Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes

(2007) Tatsuhiro Ishida et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS