Efficient and targeted delivery of siRNA in vivo

Staying on message: design principles for controlling nonspecific responses to siRNA

(2010) Shirley Samuel-Abraham et al.   FEBS Journal

Designing highly active siRNAs for therapeutic applications

(2010) S. Patrick Walton et al.   FEBS Journal

RNA interference in vitro and in vivo using an arginine peptide/siRNA complex system

(2010) Sung Wook Kim et al.   JOURNAL OF CONTROLLED RELEASE

siRNA delivery systems for cancer treatment

(2009) Yu-Kyoung Oh et al.   ADVANCED DRUG DELIVERY REVIEWS

Acid-Responsive Linear Polyethylenimine for Efficient, Specific, and Biocompatible siRNA Delivery

(2009) Min Suk Shim et al.   BIOCONJUGATE CHEMISTRY

The systemic delivery of siRNAs by a cell penetrating peptide, low molecular weight protamine

(2009) Young-Suk Choi et al.   BIOMATERIALS

Tat-BMPs-PAMAM Conjugates Enhance Therapeutic Effect of Small Interference RNA on U251 Glioma Cells In Vitro and In Vivo

(2009) Lei Han et al.   HUMAN GENE THERAPY

A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo

(2009) Hiroto Hatakeyama et al.   JOURNAL OF CONTROLLED RELEASE

In vivo siRNA delivery with dendritic poly(l-lysine) for the treatment of hypercholesterolemia

(2009) Kazuto Watanabe et al.   Molecular BioSystems

Biological Barriers to Therapy with Antisense and siRNA Oligonucleotides

(2009) R. Juliano et al.   MOLECULAR PHARMACEUTICS

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth

(2009) L. Crombez et al.   NUCLEIC ACIDS RESEARCH

Virion-Mimicking Nanocapsules from pH-Controlled Hierarchical Self-Assembly for Gene Delivery

(2008) Peisheng Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cellular siRNA Delivery Mediated by a Cell-Permeant RNA-Binding Protein and Photoinduced RNA Interference

(2008) Tamaki Endoh et al.   BIOCONJUGATE CHEMISTRY

Acetal Linked Oligoethylenimines for Use As pH-Sensitive Gene Carriers

(2008) Veronika Knorr et al.   BIOCONJUGATE CHEMISTRY

Application of an HIV gp41-Derived Peptide for Enhanced Intracellular Trafficking of Synthetic Gene and siRNA Delivery Vehicles

(2008) Ester J. Kwon et al.   BIOCONJUGATE CHEMISTRY

siRNA Conjugate Delivery Systems

(2008) Ji Hoon Jeong et al.   BIOCONJUGATE CHEMISTRY

Silencing HIV-1 In Vivo

(2008) Frank Kirchhoff   CELL

Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo

(2008) Miriam Breunig et al.   JOURNAL OF CONTROLLED RELEASE

Therapeutic Targeting of Neuropilin-2 on Colorectal Carcinoma Cells Implanted in the Murine Liver

(2008) M. J. Gray et al.   JNCI-Journal of the National Cancer Institute

Novel Dual Inhibitory Function Aptamer–siRNA Delivery System for HIV-1 Therapy

(2008) Jiehua Zhou et al.   MOLECULAR THERAPY

Chitosan/siRNA Nanoparticle–mediated TNF-α Knockdown in Peritoneal Macrophages for Anti-inflammatory Treatment in a Murine Arthritis Model

(2008) Kenneth A Howard et al.   MOLECULAR THERAPY

Direct CNS Delivery of siRNA Mediates Robust Silencing in Oligodendrocytes

(2008) William Querbes et al.   OLIGONUCLEOTIDES

Systemic Leukocyte-Directed siRNA Delivery Revealing Cyclin D1 as an Anti-Inflammatory Target

(2008) D. Peer et al.   SCIENCE

Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles

(2007) Shyh-Dar Li et al.   JOURNAL OF CONTROLLED RELEASE