Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway

Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma

(2012) Luca Busino et al.   NATURE CELL BIOLOGY

MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression

(2011) Mikael Lerner et al.   CELL CYCLE

Enhanced Information Output From Shotgun Proteomics Data by Protein Quantification and Peptide Quality Control (PQPQ)

(2011) Jenny Forshed et al.   MOLECULAR & CELLULAR PROTEOMICS

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

(2011) Hiroyuki Inuzuka et al.   NATURE

Evolutionary Conserved Regulation of HIF-1β by NF-κB

(2011) Patrick van Uden et al.   PLoS Genetics

Non-canonical NF-κB signaling pathway

(2010) Shao-Cong Sun   CELL RESEARCH

A single NFκB system for both canonical and non-canonical signaling

(2010) Vincent Feng-Sheng Shih et al.   CELL RESEARCH

The Fbw7/Human CDC4 Tumor Suppressor Targets Proproliferative Factor KLF5 for Ubiquitination and Degradation through Multiple Phosphodegron Motifs

(2010) Ning Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ongoing and future developments at the Universal Protein Resource

(2010)   NUCLEIC ACIDS RESEARCH

Tumor suppressor Fbxw7 regulates TGFβ signaling by targeting TGIF1 for degradation

(2010) M T Bengoechea-Alonso et al.   ONCOGENE

Oncogenic Activation of NF- B

(2010) L. M. Staudt   Cold Spring Harbor Perspectives in Biology

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

(2009) Monique L Den Boer et al.   LANCET ONCOLOGY

The Fbxw7/hCdc4 tumor suppressor in human cancer

(2008) YingMeei Tan et al.   CANCER LETTERS

Quantitative membrane proteomics applying narrow range peptide isoelectric focusing for studies of small cell lung cancer resistance mechanisms

(2008) Hanna Eriksson et al.   PROTEOMICS

FBXW7 Targets mTOR for Degradation and Cooperates with PTEN in Tumor Suppression

(2008) Jian-Hua Mao et al.   SCIENCE