Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma

Both SCFCdc4αand SCFCdc4γare required for cyclin E turnover in cell lines that don’t overexpress cyclin E

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MCL1 meets its end during mitotic arrest

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Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

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Initial genome sequencing and analysis of multiple myeloma

(2011) Michael A. Chapman et al.   NATURE

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)

(2011) Konstantinos J Mavrakis et al.   NATURE GENETICS

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF- B-dependent lymphoma

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Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun

(2010) Joerg D Hoeck et al.   NATURE NEUROSCIENCE

Negative Feedback in Noncanonical NF- B Signaling Modulates NIK Stability Through IKK -Mediated Phosphorylation

(2010) B. Razani et al.   Science Signaling

Oncogenic Activation of NF- B

(2010) L. M. Staudt   Cold Spring Harbor Perspectives in Biology

SnapShot: F Box Proteins I

(2009) Jeffrey R. Skaar et al.   CELL

Kinetic control of negative feedback regulators of NF- B/RelA determines their pathogen- and cytokine-receptor signaling specificity

(2009) V. F.-S. Shih et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7

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