Proteomic Analysis Reveals a Role for Bcl2-associated Athanogene 3 and Major Vault Protein in Resistance to Apoptosis in Senescent Cells by Regulating ERK1/2 Activation

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

(2016) Lioubov G. Korotchkina et al.   Aging-US

Oncogene-induced senescence: An essential role for Runx

(2014) Anne Terry et al.   CELL CYCLE

Genetic Susceptibility to Triple-Negative Breast Cancer

(2013) K. N. Stevens et al.   CANCER RESEARCH

Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy

(2013) Anna Ulbricht et al.   CURRENT BIOLOGY

Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation

(2013) X. Deschenes-Simard et al.   GENES & DEVELOPMENT

The Stress Protein BAG3 Stabilizes Mcl-1 Protein and Promotes Survival of Cancer Cells and Resistance to Antagonist ABT-737

(2013) Mariana Boiani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy

(2013) Jan R. Dörr et al.   NATURE

BAG3 induction is required to mitigate proteotoxicity via selective autophagy following inhibition of constitutive protein degradation pathways

(2013) F Rapino et al.   ONCOGENE

p53-Mediated Senescence Impairs the Apoptotic Response to Chemotherapy and Clinical Outcome in Breast Cancer

(2012) James G. Jackson et al.   CANCER CELL

Toward objective evaluation of proteomic algorithms

(2012) John R Yates et al.   NATURE METHODS

BAG3 controls angiogenesis through regulation of ERK phosphorylation

(2012) A Falco et al.   ONCOGENE

Spatio-temporal association between mTOR and autophagy during cellular senescence

(2011) Andrew R.J. Young et al.   Autophagy

BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins

(2011) Martin Gamerdinger et al.   EMBO REPORTS

BAG3: a multifaceted protein that regulates major cell pathways

(2011) A Rosati et al.   Cell Death & Disease

MVP interacts with YPEL4 and inhibits YPEL4-mediated activities of the ERK signal pathway

(2010) Pei Liang et al.   Biochemistry and Cell Biology

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

(2009) Martin Gamerdinger et al.   EMBO JOURNAL

Targeting major vault protein in senescence-associated apoptosis resistance

(2009) Sung Jin Ryu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Eating to exit: autophagy-enabled senescence revealed

(2009) E. White et al.   GENES & DEVELOPMENT

Autophagy mediates the mitotic senescence transition

(2009) A. R.J. Young et al.   GENES & DEVELOPMENT

HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins

(2009) Aaron T. Jacobs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rb2/p130 is the dominating pocket protein in the p53–p21 DNA damage response pathway leading to senescence

(2009) H Helmbold et al.   ONCOGENE

On the role of major vault protein in the resistance of senescent human diploid fibroblasts to apoptosis

(2008) S J Ryu et al.   CELL DEATH AND DIFFERENTIATION

Tumour cell survival signalling by the ERK1/2 pathway

(2008) K Balmanno et al.   CELL DEATH AND DIFFERENTIATION

Vaults and the major vault protein: Novel roles in signal pathway regulation and immunity

(2008) W. Berger et al.   CELLULAR AND MOLECULAR LIFE SCIENCES