Identification of a Metabolizing Enzyme in Human Kidney by Proteomic Correlation Profiling

Purification and Identification of Activating Enzymes of CS-0777, a Selective Sphingosine 1-Phosphate Receptor 1 Modulator, in Erythrocytes

(2011) Kiyoaki Yonesu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological Modulation of Peripheral T and B Lymphocytes by a Selective Sphingosine 1-Phosphate Receptor-1 Modulator

(2011) James B. Moberly et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Discovery of CS-0777: A Potent, Selective, and Orally Active S1P1 Agonist

(2011) Takahide Nishi et al.   ACS Medicinal Chemistry Letters

Fingolimod for relapsing multiple sclerosis: an update

(2010) Alejandro Horga et al.   EXPERT OPINION ON PHARMACOTHERAPY

MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake

(2010) Fabiana Perocchi et al.   NATURE

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

(2010) Volker Brinkmann et al.   NATURE REVIEWS DRUG DISCOVERY

Ketoconazole Increases Fingolimod Blood Levels in a Drug Interaction via CYP4F2 Inhibition

(2009) John M. Kovarik et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Combination of MS Protein Identification and Bioassay of Chromatographic Fractions to Identify Biologically Active Substances from Complex Protein Sources

(2009) Sadao Kuromitsu et al.   MOLECULAR & CELLULAR PROTEOMICS

Sensitive multiplexed analysis of kinase activities and activity-based kinase identification

(2009) Kazuishi Kubota et al.   NATURE BIOTECHNOLOGY

A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics

(2009) Jürgen Cox et al.   Nature Protocols

Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules

(2009) David Marsolais et al.   NATURE REVIEWS DRUG DISCOVERY

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Discovery of a Cytokine and Its Receptor by Functional Screening of the Extracellular Proteome

(2008) H. Lin et al.   SCIENCE