Article
Chemistry, Analytical
Andrew K. Schug, Diane Beauchemin
Summary: A new method was developed for the direct analysis of rock samples to ensure accurate results, showing that using a specific concentration of surfactant can improve the reproducibility of sample introduction.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2021)
Article
Environmental Sciences
Rajendran Shalini, Geevaretnam Jeyasekaran, Robinson Jeya Shakila, Ulaganathan Arisekar
Summary: The study found that the main accumulation organs of trace elements in commercially important fish along the southeast coast of India are different, and the concentration of toxic trace elements in the edible portion is lower than the international legislation limits.
MARINE POLLUTION BULLETIN
(2021)
Article
Chemistry, Analytical
Selena Carretero-Pena, M. R. Palomo-Marin, Lorenzo Calvo-Blazquez, Eduardo Pinilla-Gil
Summary: The study demonstrates the overall applicability of the novel sonoreactor VialTweeter as a tool for extracting trace elements from soil samples in environmental monitoring. The proposed sonoreactor-assisted extraction methodology offers advantages of shorter pretreatment time and reduced sample and reagent usage compared to standard acid digestion. Validation results against the standard acid digestion vary for different analytes, with cadmium showing the best results without systematic error. Corrections are required for copper, lead, arsenic, and zinc determination when using the proposed US extraction plus ICP-MS.
Article
Nutrition & Dietetics
Rui Azevedo, Davide Gennaro, Mary Duro, Edgar Pinto, Agostinho Almeida
Summary: Previous studies have shown that haemodialysis patients have an increased risk of trace element imbalances. In this study, both serum and whole blood concentrations of a wide panel of trace elements in haemodialysis patients were determined and compared with those of a control group. The results indicate that chronic haemodialysis may affect intra- and extracellular blood compartments differently, leading to significant trace element imbalances.
Article
Engineering, Environmental
Feiyun Tou, Zuoshun Niu, Jiquan Fu, Jiayuan Wu, Min Liu, Yi Yang
Summary: This study developed a simple standardized protocol for separating and analyzing metal-containing NPs in sediment samples using SP-ICP-MS technique. The separation efficiency of NPs and large particles in sediments was recommended with a settling time of 6 hours, and optimal sediment to water ratio, ultrasonication power, time, and temperature were determined. The recoveries of spiked Ag and Au-NPs were 71.4% and 81.1% using the optimized method.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Environmental Sciences
Marcus von der Au, Tristan Zimmermann, Ulrike Kleeberg, Wolf von Tuempling, Daniel Proefrock
Summary: The study analyzed trace elements in surface sediment samples collected in 2014 to assess the pollution level and changes in the Wadden Sea. Cluster analysis and principal component analysis revealed three distinct sub-catchments, and discriminant analysis confirmed the classification. The study also demonstrated the representative nature of the sampling strategy for sediment characterization.
MARINE POLLUTION BULLETIN
(2022)
Article
Food Science & Technology
Federica Gulino, Elisa Cala, Christian Cozzani, Lorenzo Vaccari, Matteo Oddone, Maurizio Aceto
Summary: Honey is highly valued for its beneficial properties, but it is also susceptible to counterfeiting. Analytical methods are being developed to verify its origin and authenticity using trace- and ultra-trace elements. Lanthanides have been found to be particularly useful for tracing the link between honey and the soil it originates from. The study used ICP-MS and ICP-OES analysis to investigate the traceability of 17 different honey chains, and found that while the soil fingerprint remains unchanged, there is slight fractionation of heavier lanthanides from flowers to honey.
Article
Geochemistry & Geophysics
Gianni Gallello, Mirco Ramacciotti, Oreto Garcia Puchol, Marco Lezzerini, Sarah B. McClure, Agustin Pastor
Summary: In this study, total and partial digestion methods were used to analyze trace elements in sediment samples from Cueva de la Cocina in Spain. Results showed that total digestion is more effective for aluminosilicates and heavy minerals, while the differences between the two methods are often irrelevant for archaeological interpretations.
Article
Environmental Sciences
Marta Herrero, Joaquim Rovira, Neus Gonzalez, Montse Marques, Fernando Barbosa, Jordi Sierra, Jose L. Domingo, Marti Nadal, Marilia Cristina Oliveira Souza
Summary: The interest in determining the chemical composition of textile products has increased due to toxicological issues and environmental concerns. This study analyzed the levels of twenty trace elements in clothing items commercialized in Spain and evaluated the potential health implication of dermal exposure in early life. Aluminum, zinc, and titanium showed the highest concentrations, while chromium was found in high levels in black polyester. Dermal exposure to titanium was associated with a hazard quotient higher than the threshold value, indicating potential risks for pregnant women and newborns.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Ixchel M. Ruiz-Hernandez, Mohammad-Zaman Nouri, Marianne Kozuch, Nancy D. Denslow, Raul E. Diaz-Gamboa, Rossanna Rodriguez-Canul, Reyna C. Colli-Dula
Summary: Bottlenose dolphins in coastal and estuarine ecosystems are exposed to multiple stressors and can bioaccumulate contaminants. This study used a lipidomics approach and trace element analysis to characterize the lipid composition and correlations with trace elements in bottlenose dolphin blubber. The results provide insights into the physiological functions and risks that anthropogenic activities pose to coastal organisms.
Article
Biochemistry & Molecular Biology
Nihal Efe Atila, Alptug Atila, Zulkuf Kaya, Yunus E. Bulut, Fatih Oner, Kubra Topal, Zafer Bayraktutan, Ebubekir Bakan
Summary: This study found that elevated levels of cadmium, manganese, and chromium, as well as reduced levels of selenium in serum, may play an important role in the etiopathogenesis of tinnitus.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Environmental Sciences
Yahya R. Tahboub, Abd Al-Majeed A. Al-Ghzawi, Shaker S. Al-Zayafdneh, Mohammad S. AlGhotani
Summary: The study revealed variations in major and trace element levels in Jordanian honey, with local honey showing higher levels of strontium and total REEs, while imported honey had very low levels of toxic elements, indicating higher safety. Discrimination between imported and local honey would require analysis of a large number of samples (>100) and use of advanced statistical models.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Geochemistry & Geophysics
Axel Muller, William Keyser, William B. Simmons, Karen Webber, Michael Wise, Hartmut Beurlen, Idoia Garate-Olave, Encarnacion Roda-Robles, Miguel Angel Galliski
Summary: Analysis of quartz from different pegmatites worldwide using LA-ICP-MS revealed that the chemistry of pegmatite quartz is mainly controlled by the source rock chemistry of pegmatite melts. Chemically primitive pegmatites may be suitable for high-tech applications, while quartz with high concentrations of Li and Al may indicate economic mineralization.
Article
Agriculture, Dairy & Animal Science
Zaneta Steiner-Bogdaszewska, Katarzyna Tajchman, Aleksandra Ukalska-Jaruga, Mariusz Florek, Monika Pecio
Summary: The research focused on analyzing the concentrations of 21 mineral elements in various tissues of farmed fallow deer, with significant differences observed in the distribution of main elements in different tissues, while trace and toxic elements were found to be more concentrated in bone tissues.
Article
Agriculture, Dairy & Animal Science
Sergey V. Kapranov, Alexander F. Kozintsev, Nikolay I. Bobko, Vitaliy I. Ryabushko
Summary: This study examined the effects of age, sampling location, and sex on the element contents in the soft tissues of Mytilus galloprovincialis. It found that most element contents decreased with age, and there were significant differences in element accumulation patterns among mussels from different sites. Sex did not significantly affect element accumulation. The ratio of soft tissue dry weight to total weight and certain morphometric parameters were strongly correlated with element contents.
Article
Chemistry, Analytical
Romulo R. Facci, Paulo S. de O. Cezario, Jefferson S. de Gois, Aderval S. Luna, Wagner F. Pacheco
Summary: This study developed a method based on synchronous fluorescence combined with chemometric tools to classify vodka samples, achieving high accuracy in distinguishing authentic from counterfeit samples. Discriminant analysis and support vector machine were successful in accurately classifying the samples, while k-nearest neighbor was not effective. Ultimately, only SVM with radial base function was able to correctly classify all brands of vodka samples using synchronous fluorescence spectroscopy.
ANALYTICAL LETTERS
(2021)
Article
Geochemistry & Geophysics
Paul Vallelonga, Jefferson S. de Gois, Daniel L. G. Borges, Marta Costas-Rodriguez, Vasileios Gkinis, Delphine Lannuzel, Andrea Spolaor, Frank Vanhaecke
Summary: This study investigated the isotopic partitioning of Br and Cl in Southern Ocean sea ice for the first time. While the concentrations of bromine and chlorine showed a positive correlation, the isotopic compositions exhibited less consistent relation and significant variability within individual ice cores. Various factors such as ice texture, age, salt content, and algal biomass content may influence isotopic fractionation processes in sea ice.
GEOCHIMICA ET COSMOCHIMICA ACTA
(2021)
Article
Engineering, Chemical
Isabel Cristina da Silva Haas, Juliana Santos de Espindola, Gabriela Rodrigues de Liz, Aderval S. Luna, Marilde T. Bordignon-Luiz, Elane Schwinden Prudencio, Jefferson Santos de Gois, Isabela Maia Toaldo Fedrigo
Summary: A three-stage block freeze concentration process was studied to concentrate minerals and polyphenols in orange juice, obtaining high concentrations in the final cryoconcentrate; the antioxidant activity of the concentrated juices increased significantly across the process stages. The third stage cryoconcentrate had the highest polyphenol content and mineral levels, showing a substantial increase compared to the initial juice.
JOURNAL OF FOOD ENGINEERING
(2022)
Article
Chemistry, Applied
Jarbas Verissimo Robert, Jefferson S. de Gois, Rodrigo Barros Rocha, Aderval S. Luna
Summary: This study aims to classify the origin of coffee samples using synchronous molecular fluorescence spectroscopy. Different strategies were performed and compared, revealing that the fusion of raw data from the 10 nm and 40 nm offset spectra yielded the best results. Linear and nonlinear methods were evaluated, with the fusion at low-level showing the most promising outcomes.
Article
Chemistry, Applied
Barbara M. de Andrade, Larissa P. Margalho, Diego B. Batista, Izylla O. Lucena, Bruna A. Kamimura, Celso F. Balthazar, Ramon Peres Brexo, Arthur K. R. Pia, Ramon A. S. Costa, Adriano G. Cruz, Daniel Granato, Anderson S. Sant'Ana, Aderval S. Luna, Jefferson S. de Gois
Summary: This study aims to determine the mineral composition of Brazilian artisanal cheese (BAC) and classify the cheese types using chemometric techniques. The results show that the mineral content of the cheese is influenced by the type of cheese, producing region, and technological process. BAC is an important source of minerals beneficial to health, and its authenticity is vital for consumers.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Article
Chemistry, Analytical
Marina Araujo Joao Lopes da Costa, Ana Paula Benevides, Deborah Vargas Cesar, Aderval S. Luna, Jefferson S. de Gois
Summary: A new procedure for arsenic preconcentration and determination using maghemite nanoparticles has been developed. The experimental conditions for hydride generation and preconcentration were optimized. The method showed high enrichment factor and low detection limit.
ANALYTICAL LETTERS
(2023)
Article
Chemistry, Analytical
Karine S. Coelho, Eduardo S. Chaves, Daniel L. G. Borges, Sindy R. Krzyzaniak, Rafael C. C. Rocha, Tatiana D. Saint' Pierre, Vera Lucia Azzolin Frescura Bascunan
Summary: Palladium nanoparticles were evaluated as a potential chemical modifier for lead determination in high-resolution continuum source graphite furnace atomic absorption spectrometry. The results showed that the use of palladium nanoparticles can improve sensitivity and thermal stability, especially when using 3 nm spherical-shaped particles.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2022)
Article
Oceanography
Heitor Evangelista, Raquel L. M. de Paula, Newton Magalhaes, Jefferson S. de Gois, Aderval S. Luna, Renata C. Cagnin, Valeria S. Quaresma, Flavia F. Bezerra, Jonathan P. Dia, Roberto V. Santos, Andre Pullen, Stefano Crivellari, Cristiano M. Chiessi, Diego B. Batista, Sergio J. Goncalves Jr, Bruno V. X. de Oliveira, Pedro A. R. Bizelli, Eduardo D. Sodre, Mariana Angonese, Anna B. J. Oaquim
Summary: Abrolhos is the largest and most diverse coral reef system in the South Atlantic. It has been affected by disturbances such as rising sea surface temperatures, El Nino events, oil spill pollution, human interventions, a mining disaster, floods, and extra-tropical cyclones. Through detailed analysis of coral samples, we detected the impacts of these events on the reef system.
CONTINENTAL SHELF RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Renan G. Marim, Gilberto S. Coelho Junior, Paola C. C. de Azevedo, Daniel L. G. Borges, Tatiane A. Maranhao, Fernando J. S. de Oliveira, Vera L. A. F. Bascunan, Eduardo S. Chaves
Summary: In this study, the assessment of chlorine, fluorine, and sulfur concentrations in depth profile of drill cuttings was performed using ion chromatography with optimized sample preparation by pyrohydrolysis. The results showed high accuracy, good precision, and suitability for drill cuttings analysis.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Analytical
Thaiane Nolasco da Silva, Diego B. Batista, Bernardo Ferreira Braz, Aderval S. Luna, Ricardo Erthal Santelli, Marcos Antonio dos Santos Fernandez, Jefferson S. de Gois
Summary: This work describes the development of microwave-assisted digestion methods for the determination of Cu and Sn in antifouling paints by ICP OES. The optimal conditions were determined by optimizing factors such as sample mass and solutions of HNO3, HF, and HCl. The microwave digestion-assisted ICP-OES method showed better performance compared to dry ashing with a muffle furnace and laser ablation-ICP-MS.
Article
Chemistry, Analytical
Marina Araujo J. Lopes da Costa, Mariana F. Costa, Rayane Sorrentino, Nakedia M. F. Carvalho, Jefferson S. de Gois
Summary: This study introduces a novel method for preconcentrating As, Cu, and Pb from seawater samples using manganese oxide octahedral molecular sieve (OMS-2). The method was optimized using ICP-OES analysis and achieved high enrichment factors and low detection limits for the target elements. The method was successfully applied to determine As, Cu, and Pb in seawater samples.
Article
Environmental Sciences
Ana Paula Nazar De Souza, Dalber R. Sanchez, Mariella Alzamora, Marcos Vinicius Colaco, Marcelo Augusto Vieira de Souza, Jefferson Santos De Gois, Jaqueline Dias Senra, Nakedia M. F. Carvalho
Summary: Contamination of water by toxic dyes is a serious environmental problem. In this study, an environmentally safe adsorbent composed of iron oxide nanoparticles and proanthocyanidins was prepared using a green synthesis method. The adsorbent showed excellent adsorption capacity for cationic dyes and could be reused for multiple cycles without loss of efficiency.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Analytical
Gilberto da S. Coelho Junior, Klaiani B. Fontana, Tatiane A. Maranhao, Daniel L. G. Borges
Summary: In this study, particulate matter (PM) impregnated with methylmercury was analyzed using atomic absorption spectrometry coupled with a customized dielectric barrier discharge (DBD) device. The combination of chemical vapor generation (CVG) and the DBD device allowed for efficient detection of methylmercury. The study also investigated the adsorption of methylmercury on PM and found that it was efficiently adsorbed. Furthermore, the feasibility of the device for methylmercury detection in the presence of Hg2+ was demonstrated.
ANALYTICAL METHODS
(2022)
Article
Chemistry, Analytical
Richard M. de Oliveira, Daniel L. G. Borges, Patricia Grinberg, Ralph E. Sturgeon
Summary: A novel high yield photochemical vapor generation (PVG) method for Os was developed, achieving a method detection limit of 0.16 pg mL(-1) and a precision of 4% (RSD) at 10 ng mL(-1). The product identity has not been confirmed but is suspected to be a carbonyl or alkyl-substituted carbonyl based on the reaction conditions and volatility difference from OsO4.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2021)
Article
Chemistry, Analytical
Richard M. de Oliveira, Daniel L. G. Borges, Patricia Grinberg, Zoltan Mester, Ralph E. Sturgeon
Summary: The presence of Cu2+ significantly enhances the photochemical vapor generation (PVG) efficiencies of both Br- and BrO3- species, with Cu2+ serving as a photocatalyst in both PVG systems. Efficient synthesis of CH3Br is achieved through a flow-through photochemical reactor, while high PVG efficiency for Br- is achieved using a germicidal lamp.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2021)
Article
Chemistry, Analytical
Michel Rocha Baqueta, Augusto Cesar Costa-Santos, Ana Paula Rebellato, Gisele Marcondes Luz, Juliana Azevedo Lima Pallone, Federico Marini, Alexsandro Lara Teixeira, Douglas N. Rutledge, Patricia Valderrama
Summary: This study reports the essential element composition of new Brazilian Canephora coffees and applies chemometric tools for analysis. The results demonstrate the suitability of this method for origin and species discrimination based on the inorganic fraction of coffee.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mengjie Li, Jiapeng Wang, You Zhou, Yang Chen, Lingying Xia
Summary: A novel photoelectrochemical biosensor based on gold nanoparticles and specific structures was developed for highly sensitive detection of mercury ion. The multiple sandwich structures hindered electron supply and light harvesting, resulting in a weakened PEC signal, while the specific structures extinguished the PEC signal, enabling quantitative detection of Hg2+. The sensor exhibited high selectivity and stability, with potential applications in environmental detection, biological analysis, and medical research.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mohamed A. Korany, Rasha M. Youssef, Marwa A. A. Ragab, Mostafa A. Afify
Summary: A stability-indicating fit-for-purpose method was developed for the determination of HC, TL, and PS in syrup dosage form. The method successfully separated CL from THY and quantified the analytes using HPLC-DAD. The robustness of the method was assessed through statistical analysis and self-validation.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Lingling Lin, Minyu Li, Ping Li, Chenqing Ye, Huanglong Zhuang, Shaohuang Weng, Feng Chen
Summary: This study developed a highly sensitive and selective electrochemical sensor for simultaneous detection of dopamine and uric acid. The sensor exhibited excellent anti-interference and stability, and could accurately measure dopamine and uric acid in human urine samples.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Peifang Chen, Caiyun Jiang, Zhouping Wang, Hong-zhen Lian, Xiaoyuan Ma
Summary: In this study, a high-performance SERS-active aptasensor was successfully developed for the quantitative analysis of AFB1 in cereal grains, which is of great significance in the field of food safety.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
E. Abas, C. Marina-Montes, C. Perez-Marin, J. Puimedon, J. Anzano
Summary: This study conducted a comprehensive measurement of natural and anthropogenic radionuclides in soil, water, and air in different locations around Deception Island in Antarctica. The results revealed significant levels of 210Pb and anthropogenic 137Cs in soil samples near old human settlements and facilities, as well as detectable levels of 137Cs and 60Co in water samples from old hunting areas. The findings also suggested potential resuspension processes based on higher-than-expected air quality results.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Joao Franciso Allochio, Nayara A. dos Santos, Nathalia dos S. Conceicao, Clara S. D. Baptista, Keyller B. Borges, Valdemar Lacerda Jr, Wanderson Roma
Summary: This study developed a fiber spray ionization mass spectrometry (FSI-MS) method, which shows great potential in detecting illicit drugs. Compared with paper spray ionization mass spectrometry (PSI-MS), FSI-MS demonstrates higher sensitivity in COC detection.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Dina A. Ahmed, Ola G. Hussein, Mamdouh R. Rezk, Mohamed Abdelkawy, Yasmin Rostom
Summary: The main goal of this study was to develop two green chromatographic techniques, HPLC and TLC, for the determination of alcaftadine (ALF) in pharmaceutical formulation and biological samples. The developed HPLC technique showed high efficiency and minimal environmental impact, successfully identifying ALF in the presence of its degradate. The TLC method provided a stability indicating study for ALF and was determined to be safe, green, and eco-friendly.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Abdullah Taner Bisgin
Summary: A green, speedy, and handy method for separation and determination of four commonly used food colorants was established using vortex assisted sequential-simultaneous liquid phase micro-extraction (VA-SS-LPME). The method does not require any instrumental chromatographic techniques. The procedure includes sequential separation steps using different extractants and simultaneous UV-vis spectrophotometric determination steps. The method is environmentally friendly and applicable for determination of colorants in food and pharmaceuticals.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Yifan Zhang, Tong Zhang, Wenjing Ba, Li Liu, Yuan Rao, Xiaodan Zhang, Hanhan Zhang, Xiu Jin
Summary: This paper proposes a novel spectral transfer modelling method based on neural network architecture searching for the asymptomatic prediction of Akizuki pear cork spot disorder. The experiments show that the model by this method is more effective, achieving an accuracy of 82.61%.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Krzysztof Greda, Maja Welna, Anna Szymczycha-Madeja, Pawel Pohl
Summary: For the first time, a dispersive micro-solid phase extraction (D-mu SPE) based on graphene oxide was used for the ultrasensitive determination of Cd. With this method, Cd can be efficiently extracted from a mixture of alkali and alkaline earth metals without the need for an elution step. The combination of D-mu SPE and SAGD OES significantly reduces matrix effects and improves the tolerance of Cd to alkali metals. The method shows simplicity in the measurement system and the commercially available nanosorbent used.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
P. K. Fathima Anjila, G. R. Tharani, Anand Sundaramoorthy, Venkat Kumar Shanmugam, Karthikeyan Subramani, Shanmugavel Chinnathambi, Ganesh N. Pandian, Vimala Raghavan, Andrews Nirmala Grace, Singaravelu Ganesan, Mangaiyarkarasi Rajendiran
Summary: This work proposes a rapid and sensitive spectroscopic method for detecting melamine in food products using rare-earth Terbium-doped Graphene Quantum Dots (Tb-GQDs) synthesized by microwave and simple chemical conjugation methods. The synthesized Tb-GQDs show a spherical shape with a size of approximately 6 nm and a quantum yield of 52%. The maximum detection limit for melamine concentration in milk and milk products is found to be 0.31 μM. The dual emitting Tb-GQDs provide a sensitive and effective platform for real-time detection of melamine in food samples, particularly in milk, and show promising potential in the food industry.
MICROCHEMICAL JOURNAL
(2024)
Review
Chemistry, Analytical
Piyush Dey, Mandeep Kaur, Akhil Khajuria, Dilmeet Kaur, Manpreet Singh, Hema Kumari Alajangi, Neha Singla, Gurpal Singh, Ravi Pratap Barnwal
Summary: Environmental issues, such as the uncontrolled release of dangerous pollutants, have significant impacts on human health. Traditional methods for detecting pollutants require specialized personnel and equipment, but nanotechnology has improved the performance of biosensors. This article discusses the use of nanotechnology in pollutant detection and the associated techniques.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Sa Dong, Qiuyun Shi, Lingjun Guan, Yulong Wang, Pengyan Liu, Cunzheng Zhang, Jianguo Feng
Summary: In this study, a highly sensitive indirect competitive chemiluminescence enzyme immunoassay (icCLEIA) method was developed for the determination of sodium pentachlorophenolate (PCP-Na) and its metabolite pentachlorophenol (PCP). The method showed high specificity and affinity with a detection limit of 0.0032 ng/mL for PCP-Na and 0.0192 ng/mL for PCP. The method had no cross reaction with other chlorophenols compounds except for PCP. The average recoveries in chicken, pork and fish samples were 81.3-105.8% with low coefficient of variation (CV).
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Palaniappan Ilayaraja, Murugan Manivannan, Paramasivam Parthiban
Summary: Nirmatrelvir, an antiviral drug used for the treatment of COVID-19, has been recommended by the World Health Organization. We developed an optimized analytical method for the quantification of Nirmatrelvir and its products, with high sensitivity and a wide linear range. The method also meets the requirements for greenness evaluation.
MICROCHEMICAL JOURNAL
(2024)
