Disrupting folate metabolism reduces the capacity of bacteria in exponential growth to develop persisters to antibiotics

A genetic determinant of persister cell formation in bacterial pathogens

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(2017) Robert A. Fisher et al.   NATURE REVIEWS MICROBIOLOGY

Enhanced respiration prevents drug tolerance and drug resistance inMycobacterium tuberculosis

(2017) Catherine Vilchèze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Threshold effect of growth rate on population variability ofEscherichia colicell lengths

(2017) Manasi S. Gangan et al.   Royal Society Open Science

Trimethoprim-Sulfamethoxazole Prophylaxis During Live Malaria Sporozoite Immunization Induces Long-Lived, Homologous, and Heterologous Protective Immunity Against Sporozoite Challenge

(2016) Charlotte V. Hobbs et al.   JOURNAL OF INFECTIOUS DISEASES

Enhanced Efflux Activity Facilitates Drug Tolerance in Dormant Bacterial Cells

(2016) Yingying Pu et al.   MOLECULAR CELL

High Persister Mutants in Mycobacterium tuberculosis

(2016) Heather L. Torrey et al.   PLoS One

Mechanisms of bacterial persistence during stress and antibiotic exposure

(2016) Alexander Harms et al.   SCIENCE

Antibacterial Antifolates: From Development through Resistance to the Next Generation

(2016) Alexavier Estrada et al.   Cold Spring Harbor Perspectives in Medicine

Thymineless Death Lives On: New Insights into a Classic Phenomenon

(2015) Arkady Khodursky et al.   Annual Review of Microbiology

Persister Heterogeneity Arising from a Single Metabolic Stress

(2015) Stephanie M. Amato et al.   CURRENT BIOLOGY

FactoMineR: AnRPackage for Multivariate Analysis

(2015) Sébastien Lê et al.   Journal of Statistical Software

Phenotypic Variation of Salmonella in Host Tissues Delays Eradication by Antimicrobial Chemotherapy

(2014) Beatrice Claudi et al.   CELL

Quantitative flux analysis reveals folate-dependent NADPH production

(2014) Jing Fan et al.   NATURE

Identification of Anti-virulence Compounds That Disrupt Quorum-Sensing Regulated Acute and Persistent Pathogenicity

(2014) Melissa Starkey et al.   PLoS Pathogens

Dormancy Is Not Necessary or Sufficient for Bacterial Persistence

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Controlling persister cells of Pseudomonas aeruginosa PDO300 by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one

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The folate metabolic network of Falciparum malaria

(2013) J. Enrique Salcedo-Sora et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

A Quorum Sensing Small Volatile Molecule Promotes Antibiotic Tolerance in Bacteria

(2013) Yok-Ai Que et al.   PLoS One

Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance

(2012) Nitzan Gonen et al.   DRUG RESISTANCE UPDATES

Reverting Antibiotic Tolerance of Pseudomonas aeruginosa PAO1 Persister Cells by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one

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Selective Killing of Bacterial Persisters by a Single Chemical Compound without Affecting Normal Antibiotic-Sensitive Cells

(2011) Jun-Seob Kim et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel reference genes for quantifying transcriptional responses of Escherichia coli to protein overexpression by quantitative PCR

(2011) Kang Zhou et al.   BMC MOLECULAR BIOLOGY

Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism

(2011) Kristin N. Adams et al.   CELL

Age of Inoculum Strongly Influences Persister Frequency and Can Mask Effects of Mutations Implicated in Altered Persistence

(2011) H. Luidalepp et al.   JOURNAL OF BACTERIOLOGY

Bacterial Conversion of Folinic Acid Is Required for Antifolate Resistance

(2011) Sam Ogwang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies

(2011) M. Fauvart et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Metabolite-enabled eradication of bacterial persisters by aminoglycosides

(2011) Kyle R. Allison et al.   NATURE

Persister Cells

(2010) Kim Lewis   Annual Review of Microbiology

Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism

(2010) Anne S. Tibbetts et al.   Annual Review of Nutrition

The Frequency of Persisters in Escherichia coli Reflects the Kinetics of Awakening from Dormancy

(2010) A. Joers et al.   JOURNAL OF BACTERIOLOGY

Artemisinin‐Induced Dormancy inPlasmodium falciparum: Duration, Recovery Rates, and Implications in Treatment Failure

(2010) Franka Teuscher et al.   JOURNAL OF INFECTIOUS DISEASES

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Role of Global Regulators and Nucleotide Metabolism in Antibiotic Tolerance in Escherichia coli

(2008) S. Hansen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Folate in Wheat Genotypes in the HEALTHGRAIN Diversity Screen

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