Building-in biosafety for synthetic biology

Bacterial Persistence and Toxin-Antitoxin Loci

(2012) Kenn Gerdes et al.   Annual Review of Microbiology

Recent advances in genetic code engineering in Escherichia coli

(2012) Michael Georg Hoesl et al.   CURRENT OPINION IN BIOTECHNOLOGY

Correlation Between Upstream Human Activities and Riverine Antibiotic Resistance Genes

(2012) Amy Pruden et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Synthetic constructs in/for the environment: Managing the interplay between natural and engineered Biology

(2012) Markus Schmidt et al.   FEBS LETTERS

Four steps to avoid a synthetic-biology disaster

(2012) Genya V. Dana et al.   NATURE

Chemical biology: DNA's new alphabet

(2012) Roberta Kwok   NATURE

Evidence of non-random mutation rates suggests an evolutionary risk management strategy

(2012) Iñigo Martincorena et al.   NATURE

Rationally designed families of orthogonal RNA regulators of translation

(2012) Vivek K Mutalik et al.   Nature Chemical Biology

Identification and classification of bacterial Type III toxin–antitoxin systems encoded in chromosomal and plasmid genomes

(2012) Tim R. Blower et al.   NUCLEIC ACIDS RESEARCH

The Standard European Vector Architecture (SEVA): a coherent platform for the analysis and deployment of complex prokaryotic phenotypes

(2012) Rafael Silva-Rocha et al.   NUCLEIC ACIDS RESEARCH

Embedding Permanent Watermarks in Synthetic Genes

(2012) Michael Liss et al.   PLoS One

Type I toxin-antitoxin systems inBacillus subtilis

(2012) Sylvain Durand et al.   RNA Biology

Thepartoxin-antitoxin system fromEnterococcus faecalisplasmid pAD1 and its chromosomal homologs

(2012) Keith E. Weaver   RNA Biology

Reprogramming the Genetic Code

(2012) J. W. Chin   SCIENCE

Synthetic Genetic Polymers Capable of Heredity and Evolution

(2012) V. B. Pinheiro et al.   SCIENCE

Biochemical Diversification through Foreign Gene Expression in Bdelloid Rotifers

(2012) Chiara Boschetti et al.   PLoS Genetics

Assessing the Probability of Detection of Horizontal Gene Transfer Events in Bacterial Populations

(2012) Jeffrey P. Townsend et al.   Frontiers in Microbiology

Engineering microbial consortia to enhance biomining and bioremediation

(2012) Karl D. Brune et al.   Frontiers in Microbiology

Chemical Evolution of a Bacterium’s Genome

(2011) Philippe Marlière et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Toxin-Antitoxin Systems in Bacteria and Archaea

(2011) Yoshihiro Yamaguchi et al.   Annual Review of Genetics

Toxins-antitoxins: diversity, evolution and function

(2011) Finbarr Hayes et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Genetically engineered bacteria: An emerging tool for environmental remediation and future research perspectives

(2011) Jay Shankar Singh et al.   GENE

ε/ζ systems: their role in resistance, virulence, and their potential for antibiotic development

(2011) Hannes Mutschler et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Amplification, Mutation, and Sequencing of a Six-Letter Synthetic Genetic System

(2011) Zunyi Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A processed noncoding RNA regulates an altruistic bacterial antiviral system

(2011) Tim R Blower et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement

(2011) Farren J. Isaacs et al.   SCIENCE

Rapid optimization of gene dosage in E. coli using DIAL strains

(2011) Joshua T Kittleson et al.   Journal of Biological Engineering

Adding New Chemistries to the Genetic Code

(2010) Chang C. Liu et al.   Annual Review of Biochemistry

Persister Cells

(2010) Kim Lewis   Annual Review of Microbiology

Environmental biosafety in the age of Synthetic Biology: Do we really need a radical new approach?

(2010) Victor de Lorenzo   BIOESSAYS

Xenobiology: A new form of life as the ultimate biosafety tool

(2010) Markus Schmidt   BIOESSAYS

BACTIBASE second release: a database and tool platform for bacteriocin characterization

(2010) Riadh Hammami et al.   BMC MICROBIOLOGY

parD toxin-antitoxin system of plasmid R1 - basic contributions, biotechnological applications and relationships with closely-related toxin-antitoxin systems

(2010) Elizabeth Diago-Navarro et al.   FEBS Journal

Antibiotic-free selection in E. coli: new considerations for optimal design and improved production

(2010) Isabelle Peubez et al.   Microbial Cell Factories

Txe, an endoribonuclease of the enterococcal Axe-Txe toxin-antitoxin system, cleaves mRNA and inhibits protein synthesis

(2010) E. M. Halvorsen et al.   MICROBIOLOGY-SGM

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

(2010) Heinz Neumann et al.   NATURE

Synthetic biology: applications come of age

(2010) Ahmad S. Khalil et al.   NATURE REVIEWS GENETICS

TADB: a web-based resource for Type 2 toxin–antitoxin loci in bacteria and archaea

(2010) Yucheng Shao et al.   NUCLEIC ACIDS RESEARCH

Holin triggering in real time

(2010) R. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tracking, tuning, and terminating microbial physiology using synthetic riboregulators

(2010) J. M. Callura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Micron-scale holes terminate the phage infection cycle

(2010) J. S. Dewey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

(2010) D. G. Gibson et al.   SCIENCE

Designing and engineering evolutionary robust genetic circuits

(2010) Sean C Sleight et al.   Journal of Biological Engineering

Antimicrobial resistance in hospitals: How concerned should we be?

(2009) M. R. Mulvey et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE

(2009) Cajetan Neubauer et al.   CELL

Toward Safe Genetically Modified Organisms through the Chemical Diversification of Nucleic Acids

(2009) Piet Herdewijn et al.   CHEMISTRY & BIODIVERSITY

Update on the Keio collection of Escherichia coli single-gene deletion mutants

(2009) Natsuko Yamamoto et al.   Molecular Systems Biology

Programming cells by multiplex genome engineering and accelerated evolution

(2009) Harris H. Wang et al.   NATURE

The phage abortive infection system, ToxIN, functions as a protein–RNA toxin–antitoxin pair

(2009) Peter C. Fineran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Gene Networks That Count

(2009) A. E. Friedland et al.   SCIENCE

Plasmid selection in Escherichia coli using an endogenous essential gene marker

(2008) Shan Goh et al.   BMC BIOTECHNOLOGY

Development of an antibiotic-free plasmid selection system based on glycine auxotrophy for recombinant protein overproduction in Escherichia coli

(2008) Luis Vidal et al.   JOURNAL OF BIOTECHNOLOGY

Discovery, Characterization, and Optimization of an Unnatural Base Pair for Expansion of the Genetic Alphabet

(2008) Aaron M. Leconte et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bacterial addiction module toxin Doc inhibits translation elongation through its association with the 30S ribosomal subunit

(2008) M. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel antibiotic free plasmid selection system: Advances in safe and efficient DNA therapy

(2007) Jürgen Mairhofer et al.   Biotechnology Journal