Metal-mediated DNA damage and cell death: mechanisms, detection methods, and cellular consequences

Ecotoxicity of engineered TiO2 nanoparticles to saltwater organisms: An overview

(2014) D. Minetto et al.   ENVIRONMENT INTERNATIONAL

Quantification of metal ion induced DNA damage with single cell array based assay

(2013) Yong Qiao et al.   ANALYST

Toxicity of Engineered Nanoparticles in the Environment

(2013) Melissa A. Maurer-Jones et al.   ANALYTICAL CHEMISTRY

DDB2 Suppresses Epithelial-to-Mesenchymal Transition in Colon Cancer

(2013) N. Roy et al.   CANCER RESEARCH

Zinc Promotes the Death of Hypoxic Astrocytes by Upregulating Hypoxia-Induced Hypoxia-Inducible Factor-1alpha Expression via Poly(ADP-ribose) Polymerase-1

(2013) Rong Pan et al.   CNS Neuroscience & Therapeutics

Decomposition kinetics of peroxynitrite: influence of pH and buffer

(2013) Christian Molina et al.   DALTON TRANSACTIONS

Mammalian MutY homolog (MYH or MUTYH) protects cells from oxidative DNA damage

(2013) Bor-Jang Hwang et al.   DNA REPAIR

Cadmium in blood of Tunisian men and risk of bladder cancer: interactions with arsenic exposure and smoking

(2013) Molka Feki-Tounsi et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Protective properties of tanshinone I against oxidative DNA damage and cytotoxicity

(2013) Shimiao Zhou et al.   FOOD AND CHEMICAL TOXICOLOGY

Decarbonylative Halogenation by a Vanadium Complex

(2013) Sujoy Rana et al.   INORGANIC CHEMISTRY

DNA Damage Processing by Human 8-Oxoguanine-DNA Glycosylase Mutants with the Occluded Active Site

(2013) Maria V. Lukina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxynitrite, a Stealthy Biological Oxidant

(2013) Rafael Radi   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial metabolism of reactive oxygen species

(2013) Paola Venditti et al.   MITOCHONDRION

Molecular mechanisms of Mn induced neurotoxicity: RONS generation, genotoxicity, and DNA-damage response

(2013) Julia Bornhorst et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The role of iron and reactive oxygen species in cell death

(2013) Scott J Dixon et al.   Nature Chemical Biology

The molecular mechanisms and physiological consequences of oxidative stress: lessons from a model bacterium

(2013) James A. Imlay   NATURE REVIEWS MICROBIOLOGY

Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

(2013) Jianfang Chen et al.   PLoS One

Manganese-induced oxidative DNA damage in neuronal SH-SY5Y cells: Attenuation of thymine base lesions by glutathione and N-acetylcysteine

(2013) Adrienne P. Stephenson et al.   TOXICOLOGY LETTERS

Titanium and Vanadium Complexes as Anticancer Agents

(2012) Irena Kostova   Anti-Cancer Agents in Medicinal Chemistry

Superoxide Dismutase in Redox Biology: The Roles of Superoxide and Hydrogen Peroxide

(2012) Garry R. Buettner   Anti-Cancer Agents in Medicinal Chemistry

Alterations in Brain Transition Metals in Huntington Disease

(2012) H. Diana Rosas et al.   ARCHIVES OF NEUROLOGY

Biophysical Investigation of the Ironome of Human Jurkat Cells and Mitochondria

(2012) Nema D. Jhurry et al.   BIOCHEMISTRY

Synthetic Analogues of Nickel Superoxide Dismutase: A New Role for Nickel in Biology

(2012) Ellen P. Broering et al.   BIOCHEMISTRY

Copper and Oxidative Stress in the Pathogenesis of Alzheimer’s Disease

(2012) Gözde Eskici et al.   BIOCHEMISTRY

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Zinc, Copper, Iron, and Chromium Concentrations in Young Patients with Type 2 Diabetes Mellitus

(2012) M. Basaki et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Iron toxicity in neurodegeneration

(2012) Marco T. Núñez et al.   BIOMETALS

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Profiling Cytosine Oxidation in DNA by LC-MS/MS

(2012) Francois Samson-Thibault et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Oxidative DNA Adducts Detected in Vitro from Redox Activity of Cigarette Smoke Constituents

(2012) Manicka V. Vadhanam et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Beyond Gel Electrophoresis: Microfluidic Separations, Fluorescence Burst Analysis, and DNA Stretching

(2012) Kevin D. Dorfman et al.   CHEMICAL REVIEWS

Volatile Organic Compounds of Lung Cancer and Possible Biochemical Pathways

(2012) Meggie Hakim et al.   CHEMICAL REVIEWS

Methylphenidate

(2012) David Devos et al.   CNS DRUGS

DNA damage, chromatin, and transcription: the trinity of aging

(2012) Rebecca C Burgess et al.   CURRENT OPINION IN CELL BIOLOGY

Variation in the biomolecular interactions of nickel(ii) hydrazone complexes upon tuning the hydrazide fragment

(2012) Paramasivam Krishnamoorthy et al.   DALTON TRANSACTIONS

Peroxynitrous acid: controversy and consensus surrounding an enigmatic oxidant

(2012) Willem H. Koppenol et al.   DALTON TRANSACTIONS

Copper(i) and nickel(ii) complexes with 1 : 1 vs. 1 : 2 coordination of ferrocenyl hydrazone ligands: Do the geometry and composition of complexes affect DNA binding/cleavage, protein binding, antioxidant and cytotoxic activities?

(2012) Paramasivam Krishnamoorthy et al.   DALTON TRANSACTIONS

Interactive Enhancements of Ascorbic Acid and Iron in Hydroxyl Radical Generation in Quinone Redox Cycling

(2012) Yi Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The impact of environmental metals in young urbanites’ brains

(2012) Lilian Calderón-Garcidueñas et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Metal interaction with redox regulation: an integrating concept in metal carcinogenesis?

(2012) Andrea Hartwig   FREE RADICAL BIOLOGY AND MEDICINE

Zinc Ion Enhances GABA Tea-Mediated Oxidative DNA Damage

(2012) Show-Mei Chuang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lipophilic Caffeic Acid Derivatives Protect Cells against H2O2-Induced DNA Damage by Chelating Intracellular Labile Iron

(2012) Natalia Kitsati et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mononuclear Iron Enzymes Are Primary Targets of Hydrogen Peroxide Stress

(2012) Adil Anjem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Stress and Chromium(VI) Carcinogenesis

(2012) Hua Yao et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Molecular mechanisms of chromium in alleviating insulin resistance

(2012) Yinan Hua et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Gas-Phase Studies of Substrates for the DNA Mismatch Repair Enzyme MutY

(2012) Anna Zhachkina Michelson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toxicity of vanadium on isolated rat liver mitochondria: a new mechanistic approach

(2012) Mir-Jamal Hosseini et al.   Metallomics

Undetectable role of oxidative DNA damage in cell cycle, cytotoxic and clastogenic effects of Cr(VI) in human lung cells with restored ascorbate levels

(2012) M. Reynolds et al.   MUTAGENESIS

The relationship of copper to DNA damage and damage prevention in humans

(2012) Maria C. Linder   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Assessment of Cr(VI)-Induced Cytotoxicity and Genotoxicity Using High Content Analysis

(2012) Chad M. Thompson et al.   PLoS One

Cobalt metabolism and toxicology—A brief update

(2012) Lars Ole Simonsen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Nickel (II)-induced cytotoxicity and apoptosis in human proximal tubule cells through a ROS- and mitochondria-mediated pathway

(2012) Yi-Fen Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Titanium release in serum of patients with different bone fixation implants and its interaction with serum biomolecules at physiological levels

(2011) Yoana Nuevo-Ordóñez et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Non-transferrin bound iron: A key role in iron overload and iron toxicity

(2011) Pierre Brissot et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

How far can hydroxyl radicals travel? An electrochemical study based on a DNA mediated electron transfer process

(2011) Qingqing Guo et al.   CHEMICAL COMMUNICATIONS

Generation of Guanine–Thymidine Cross-Links in DNA by Peroxynitrite/Carbon Dioxide

(2011) Byeong Hwa Yun et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Chromium in Drinking Water: Sources, Metabolism, and Cancer Risks

(2011) Anatoly Zhitkovich   CHEMICAL RESEARCH IN TOXICOLOGY

Oxidative DNA Damage Following Microsome/Cu(II)-Mediated Activation of the Estrogens, 17β-Estradiol, Equilenin, and Equilin: Role of Reactive Oxygen Species

(2011) Wendy A. Spencer et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Medicinal Chemistry of Novel Iron Chelators for the Treatment of Cancer

(2011) Zaklina Kovacevic et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Synthesis, characterization, DNA interaction and cleavage, and in vitro cytotoxicity of copper(ii) mixed-ligand complexes with 2-phenyl-3-hydroxy-4(1H)-quinolinone

(2011) Roman Buchtík et al.   DALTON TRANSACTIONS

Effect of substitution and planarity of the ligand on DNA/BSA interaction, free radical scavenging and cytotoxicity of diamagnetic Ni(ii) complexes: A systematic investigation

(2011) Palanisamy Sathyadevi et al.   DALTON TRANSACTIONS

Interaction of rac-[M(diimine)3]2+ (M = Co, Ni) complexes with CT DNA: role of 5,6-dmp ligand on DNA binding and cleavage and cytotoxicity

(2011) Sethu Ramakrishnan et al.   DALTON TRANSACTIONS

CO2 exacerbates oxygen toxicity

(2011) Benjamin Ezraty et al.   EMBO REPORTS

Accidental potassium dichromate poisoning. Toxicokinetics of chromium by ICP-MS-CRC in biological fluids and in hair

(2011) J.P. Goullé et al.   FORENSIC SCIENCE INTERNATIONAL

The redox stress hypothesis of aging

(2011) Rajindar S. Sohal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Zinc deficiency or excess within the physiological range increases genome instability and cytotoxicity, respectively, in human oral keratinocyte cells

(2011) Razinah Sharif et al.   Genes and Nutrition

Assessment of the genetic risks of a metallic alloy used in medical implants

(2011) Cristiano C. Gomes et al.   GENETICS AND MOLECULAR BIOLOGY

Trace elements in human organs and tissues and their significance for environmental monitoring

(2011) L. P. Rikhanov et al.   GEOCHEMISTRY INTERNATIONAL

Genotoxic effects of aluminum, iron and manganese in human cells and experimental systems: A review of the literature

(2011) PDL Lima et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Homologous Recombination is Activated at Early Time Points Following Exposure to Cobalt Chloride Induced Hypoxic Conditions in Saccharomyces cerevisiae

(2011) Ramesh Chand Meena et al.   INDIAN JOURNAL OF MICROBIOLOGY

Titanocene–Phosphine Derivatives as Precursors to Cytotoxic Heterometallic TiAu2and TiM (M = Pd, Pt) Compounds. Studies of Their Interactions with DNA

(2011) Jose F. González-Pantoja et al.   INORGANIC CHEMISTRY

The effect of pyrophosphate, tripolyphosphate and ATP on the rate of the Fenton reaction

(2011) Sandra Rachmilovich-Calis et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Important Role of Oxidative Stress Biomarkers in Huntington’s Disease

(2011) Isaac Túnez et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Neurophysiology and Pathology of Brain Zinc

(2011) S. L. Sensi et al.   JOURNAL OF NEUROSCIENCE

Nickel exposure induces oxidative damage to mitochondrial DNA in Neuro2a cells: the neuroprotective roles of melatonin

(2011) Shang-Cheng Xu et al.   JOURNAL OF PINEAL RESEARCH

Turn-On DNA Damage Sensors for the Direct Detection of 8-Oxoguanine and Photoproducts in Native DNA

(2011) Jennifer L. Furman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chromium-Induced Genotoxicity and Interference in Human Lymphoblastoid Cell (TK6) Repair Processes

(2011) Naouale El-Yamani et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Role of manganese in neurodegenerative diseases

(2011) Aaron B. Bowman et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Risks and benefits of copper in light of new insights of copper homeostasis

(2011) Daniel López de Romaña et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Chromate toxicity and the role of sulfur

(2011) Sara L. Holland et al.   Metallomics

Mechanisms of nickel toxicity in microorganisms

(2011) Lee Macomber et al.   Metallomics

The oxidative stress of zinc deficiency

(2011) David J. Eide   Metallomics

PELDOR analysis of enzyme-induced structural changes in damaged DNA duplexes

(2011) N. A. Kuznetsov et al.   Molecular BioSystems

Chromatin and the DNA damage response: The cancer connection

(2011) Martijn S. Luijsterburg et al.   Molecular Oncology

A facile method for the assessment of DNA damage induced by UV-activated nanomaterials

(2011) Yuka Yamazaki et al.   Nanoscale

Manganese Induces Oxidative Stress, Redox State Unbalance and Disrupts Membrane Bound ATPases on Murine Neuroblastoma Cells In Vitro: Protective Role of Silymarin

(2011) Yassine Chtourou et al.   NEUROCHEMICAL RESEARCH

Characterization of 2′-deoxyguanosine oxidation products observed in the Fenton-like system Cu(ii)/H2O2/reductant in nucleoside and oligodeoxynucleotide contexts

(2011) Aaron M. Fleming et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Titanium dioxide-assisted photocatalytic induction of prophages to lytic cycle

(2011) Ekaterina V. Skorb et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Iron, oxidative stress and the example of solar ultraviolet A radiation

(2011) Asma Aroun et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Advances in metal-induced oxidative stress and human disease

(2011) Klaudia Jomova et al.   TOXICOLOGY

Oxidative stress and oxidative damage in chemical carcinogenesis

(2011) James E. Klaunig et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Co-exposure to nickel and cobalt chloride enhances cytotoxicity and oxidative stress in human lung epithelial cells

(2011) Eshan Patel et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

DNA damage induction in human cells exposed to vanadium oxides in vitro

(2011) Juan J. Rodríguez-Mercado et al.   TOXICOLOGY IN VITRO

Signaling cascades mediate astrocyte death induced by zinc

(2011) Su-Lan Liao et al.   TOXICOLOGY LETTERS

A Manganese–Porphyrin Complex Decomposes H2O2, Inhibits Apoptosis, and Acts as a Radiation Mitigator in Vivo

(2011) Detcho A. Stoyanovsky et al.   ACS Medicinal Chemistry Letters

The role of porphyrin chemistry in tumor imaging and photodynamic therapy

(2010) Manivannan Ethirajan et al.   CHEMICAL SOCIETY REVIEWS

The role of reactive oxygen species and oxidative stress in environmental carcinogenesis and biomarker development

(2010) Dominique Ziech et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Oxovanadium(iv) complexes of phenanthroline bases: the dipyridophenazine complex as a near-IR photocytotoxic agent

(2010) Pijus K. Sasmal et al.   DALTON TRANSACTIONS

Photocytotoxicity and DNA cleavage activity of l-arg and l-lys Schiff base oxovanadium(iv) complexes having phenanthroline bases

(2010) Pijus K. Sasmal et al.   DALTON TRANSACTIONS

Cobalt(ii) complexes of terpyridine bases as photochemotherapeutic agents showing cellular uptake and photocytotoxicity in visible light

(2010) Sovan Roy et al.   DALTON TRANSACTIONS

Inactivation of MS2 coliphage in Fenton and Fenton-like systems: role of transition metals, hydrogen peroxide and sunlight

(2010) Jessica I. Nieto-Juarez et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Differential toxicity of Mn2+ and Mn3+ to rat liver tissues: Oxidative damage, membrane fluidity and histopathological changes

(2010) Peili Huang et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

A synergistic effect of GABA tea and copper(II) on DNA breakage in human peripheral lymphocytes

(2010) Hsueh-Fang Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

Interaction of Cationic Nickel and Manganese Porphyrins with the Minor Groove of DNA

(2010) Carmen Romera et al.   INORGANIC CHEMISTRY

Biological assays and noncovalent interactions of pyridine-2-carbaldehyde thiosemicarbazonecopper(II) drugs with [poly(dA–dT)]2, [poly(dG–dC)]2, and calf thymus DNA

(2010) Rebeca Ruiz et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Chromium is not an essential trace element for mammals: effects of a “low-chromium” diet

(2010) Kristin R. Di Bona et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

DNA-Mediated Charge Transport in Redox Sensing and Signaling

(2010) Joseph C. Genereux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The hazards of iron loading

(2010) Eugene D. Weinberg   Metallomics

Copper handling machinery of the brain

(2010) Svetlana Lutsenko et al.   Metallomics

Hydrogen peroxide inactivates the Escherichia coli Isc iron-sulphur assembly system, and OxyR induces the Suf system to compensate

(2010) Soojin Jang et al.   MOLECULAR MICROBIOLOGY

Methods for detection and measurement of hydrogen peroxide inside and outside of cells

(2010) Sue Goo Rhee et al.   MOLECULES AND CELLS

Genotoxic effects of two nickel-compounds in somatic cells of Drosophila melanogaster

(2010) Erico R. Carmona et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Nitric oxide and neuronal death

(2010) Guy C. Brown   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Cr(VI) induces mitochondrial-mediated and caspase-dependent apoptosis through reactive oxygen species-mediated p53 activation in JB6 Cl41 cells

(2010) Young-Ok Son et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

An autism cohort study of cobalt levels following vitamin B12 injections

(2010) David A. Geier et al.   TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY

Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches

(2009) Candice E. Paulsen et al.   ACS Chemical Biology

A novel approach to the identification and quantitative elemental analysis of amyloid deposits—Insights into the pathology of Alzheimer’s disease

(2009) Reshmi Rajendran et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Investigating the Biochemical Impact of DNA Damage with Structure-Based Probes: Abasic Sites, Photodimers, Alkylation Adducts, and Oxidative Lesions

(2009) Heidi A. Dahlmann et al.   BIOCHEMISTRY

Superoxide dismutases—a review of the metal-associated mechanistic variations

(2009) Isabel A. Abreu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Protective Effects of Salidroside on Endothelial Cell Apoptosis Induced by Cobalt Chloride

(2009) Chu-Bing Tan et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Mammalian iron transport

(2009) Gregory Jon Anderson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Tandem Mass Spectrometry-Based Detection of C4′-Oxidized Abasic Sites at Specific Positions in DNA Fragments

(2009) Goutam Chowdhury et al.   CHEMICAL RESEARCH IN TOXICOLOGY

An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

(2009) Kent S. Gates   CHEMICAL RESEARCH IN TOXICOLOGY

Mechanism of DNA−Protein Cross-Linking by Chromium

(2009) Andrea Macfie et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Manganese-Induced Dopaminergic Neurodegeneration: Insights into Mechanisms and Genetics Shared with Parkinson’s Disease

(2009) Alexandre Benedetto et al.   CHEMICAL REVIEWS

Nickel Homeostasis and Nickel Regulation: An Overview

(2009) Yanjie Li et al.   CHEMICAL REVIEWS

In Situ Imaging of Metals in Cells and Tissues

(2009) Reagan McRae et al.   CHEMICAL REVIEWS

New Mechanistic Aspects of the Fenton Reaction

(2009) Sandra Rachmilovich-Calis et al.   CHEMISTRY-A EUROPEAN JOURNAL

Metal Complexes, their Cellular Targets and Potential for Cancer Therapy

(2009) Di Chen et al.   CURRENT PHARMACEUTICAL DESIGN

Apoptosis and anti-tumour activities of manganese(iii)-salen and -salphen complexes

(2009) Khairul I. Ansari et al.   DALTON TRANSACTIONS

DNA binding and cleavage activity of quercetin nickel(ii) complex

(2009) Jun Tan et al.   DALTON TRANSACTIONS

Toxic effects of hexaammine cobalt(III) chloride on liver and kidney in mice: Implication of oxidative stress

(2009) Amarjit S. Naura et al.   DRUG AND CHEMICAL TOXICOLOGY

Photocytotoxic Oxovanadium(IV) Complexes Showing Light-Induced DNA and Protein Cleavage Activity

(2009) Pijus K. Sasmal et al.   INORGANIC CHEMISTRY

Concentrations and correlations for eight metals in human liver

(2009) Guy E. Griesmann et al.   INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH

DNA binding and oxidative DNA damage induced by a quercetin copper(II) complex: potential mechanism of its antitumor properties

(2009) Jun Tan et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Rising Zinc: A Significant Cause of Ischemic Neuronal Death in the CA1 Region of Rat Hippocampus

(2009) Christian J Stork et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation

(2009) Jean Cadet et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

The iron-sulfur clusters of dehydratases are primary intracellular targets of copper toxicity

(2009) L. Macomber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Free Radical Theory of Aging: Implications in Male Infertility

(2009) Nisarg Desai et al.   UROLOGY

Cellular Defenses against Superoxide and Hydrogen Peroxide

(2008) James A. Imlay   Annual Review of Biochemistry

Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms

(2008) Detmar Beyersmann et al.   ARCHIVES OF TOXICOLOGY

A Quartz Crystal Microbalance Study of Polycation-Supported Single and Double Stranded DNA Surfaces

(2008) Amanda Y. Yang et al.   BIOMACROMOLECULES

Elevated copper and oxidative stress in cancer cells as a target for cancer treatment

(2008) Anshul Gupte et al.   CANCER TREATMENT REVIEWS

Recognition and Incision of Cr(III) Ligand-Conjugated DNA Adducts by the Nucleotide Excision Repair Proteins UvrABC: Importance of the Cr(III)−Purine Moiety in the Enzymatic Reaction

(2008) Hirohumi Arakawa et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Kinetic Analysis of Intracellular Concentrations of Reactive Nitrogen Species

(2008) Chang Hoon Lim et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging

(2008) Emily L. Que et al.   CHEMICAL REVIEWS

Bacterial Base Excision Repair Enzyme Fpg Recognizes Bulky N7-Substituted-FapydG Lesion via Unproductive Binding Mode

(2008) Franck Coste et al.   CHEMISTRY & BIOLOGY

DNA damage by sulfite autoxidation catalyzed by cobalt complexes

(2008) María V. Alipázaga et al.   DALTON TRANSACTIONS

Chronic nickel-induced DNA damage and cell death: The protection role of ascorbic acid

(2008) Jie Jia et al.   ENVIRONMENTAL TOXICOLOGY

Separation of oxidatively damaged DNA nucleobases and nucleosides on packed and monolith C18 columns by HPLC-UV-EC

(2008) Michele C. Kelly et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Hydroxyl radicals (OH) are associated with titanium dioxide (TiO2) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells

(2008) James F. Reeves et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Decyanation of vitamin B12 by a trafficking chaperone

(2008) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Real-Time QCM-D Approach to Monitoring Mammalian DNA Damage Using DNA Adsorbed to a Polyelectrolyte Surface

(2007) Robert J. Rawle et al.   BIOMACROMOLECULES

Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium

(2007) Konstantin Salnikow et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Photoelectrochemical Sensor for the Rapid Detection ofin SituDNA Damage Induced by Enzyme-Catalyzed Fenton Reaction

(2007) Minmin Liang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Prooxidant activity of hydroxycinnamic acids on DNA damage in the presence of Cu(II) ions: Mechanism and structure–activity relationship

(2007) Li-Fang Zheng et al.   FOOD AND CHEMICAL TOXICOLOGY

Theoretical Study of Hydrated Copper(II) Interactions with Guanine:  A Computational Density Functional Theory Study

(2007) Matěj Pavelka et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Investigating oxidative DNA damage and its repair using the comet assay

(2007) A COLLINS   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH