Independent Regulation of Na+ and K+ Balance by the Kidney

Aldosterone Paradox: Differential Regulation of Ion Transport in Distal Nephron

(2011) Juan Pablo Arroyo et al.   PHYSIOLOGY

Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models

(2010) Zhen Liu et al.   HUMAN MOLECULAR GENETICS

Activation of Na+/H+Exchanger NHE3 by Angiotensin II Is Mediated by Inositol 1,4,5-Triphosphate (IP3) Receptor-binding Protein Released with IP3(IRBIT) and Ca2+/Calmodulin-dependent Protein Kinase II

(2010) Peijian He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sodium and Potassium Balance Depends on  ENaC Expression in Connecting Tubule

(2010) B. M. Christensen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Angiotensin II diminishes the effect of SGK1 on the WNK4-mediated inhibition of ROMK1 channels

(2010) Peng Yue et al.   KIDNEY INTERNATIONAL

Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension

(2010) J. Hadchouel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WNK4 Diverts the Thiazide-sensitive NaCl Cotransporter to the Lysosome and Stimulates AP-3 Interaction

(2009) Arohan R. Subramanya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epilepsy, Ataxia, Sensorineural Deafness, Tubulopathy, andKCNJ10Mutations

(2009) Detlef Bockenhauer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Use of Diuretics in Patients with Hypertension

(2009) Michael E. Ernst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypertension of Kcnmb1−/−is linked to deficient K secretion and aldosteronism

(2009) P. Richard Grimm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway

(2009) P. San-Cristobal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by mutations in KCNJ10

(2009) U. I. Scholl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WNK Kinases, Renal Ion Transport and Hypertension

(2008) Pedro San-Cristobal et al.   AMERICAN JOURNAL OF NEPHROLOGY

Both TASK-3 and TREK-1 two-pore loop K channels are expressed in H295R cells and modulate their membrane potential and aldosterone secretion

(2008) Tanja Brenner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

WNK Kinases and Renal Sodium Transport in Health and Disease

(2008) James A. McCormick et al.   HYPERTENSION

TASK channel deletion in mice causes primary hyperaldosteronism

(2008) L. A. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA