Diverse selective regimes shape genetic diversity atADARgenes and at their coding targets

The RNA editing enzymes ADARs: mechanism of action and human disease

(2014) Sara Tomaselli et al.   CELL AND TISSUE RESEARCH

Genome-wide signals of positive selection in human evolution

(2014) D. Enard et al.   GENOME RESEARCH

Exploring the Occurrence of Classic Selective Sweeps in Humans Using Whole-Genome Sequencing Data Sets

(2014) Maud Fagny et al.   MOLECULAR BIOLOGY AND EVOLUTION

A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1

(2014) P. Barraud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human coding RNA editing is generally nonadaptive

(2014) G. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression

(2014) B. P. Fairfax et al.   SCIENCE

An Evolutionary Analysis of Antigen Processing and Presentation across Different Timescales Reveals Pervasive Selection

(2014) Diego Forni et al.   PLoS Genetics

RNA Editome in Rhesus Macaque Shaped by Purifying Selection

(2014) Jia-Yu Chen et al.   PLoS Genetics

Alu elements shape the primate transcriptome by cis-regulation of RNA editing

(2014) Chammiran Daniel et al.   GENOME BIOLOGY

Mammalian conserved ADAR targets comprise only a small fragment of the human editosome

(2014) Yishay Pinto et al.   GENOME BIOLOGY

Identifying Recent Adaptations in Large-Scale Genomic Data

(2013) Sharon R. Grossman et al.   CELL

Gene expression drives local adaptation in humans

(2013) H. B. Fraser   GENOME RESEARCH

A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes

(2013) L. Bazak et al.   GENOME RESEARCH

Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations

(2013) Hélène Quach et al.   HUMAN MOLECULAR GENETICS

A 175 Million Year History of T Cell Regulatory Molecules Reveals Widespread Selection, with Adaptive Evolution of Disease Alleles

(2013) Diego Forni et al.   IMMUNITY

Deciphering the functions and regulation of brain-enriched A-to-I RNA editing

(2013) Jin Billy Li et al.   NATURE NEUROSCIENCE

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

(2013) Jing Wang et al.   NUCLEIC ACIDS RESEARCH

RADAR: a rigorously annotated database of A-to-I RNA editing

(2013) Gokul Ramaswami et al.   NUCLEIC ACIDS RESEARCH

Adenosine-to-inosine RNA editing and human disease

(2013) William Slotkin et al.   Genome Medicine

Dyschromatosis symmetrica hereditaria with long hair on the forearms, hypo/hyperpigmented hair, and dental anomalies: Report of a novelADAR1mutation

(2012) Piranit Nik Kantaputra et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

A Fine-Scale Chimpanzee Genetic Map from Population Sequencing

(2012) A. Auton et al.   SCIENCE

A cross-species view on viruses

(2012) Sara L Sawyer et al.   Current Opinion in Virology

Detecting Individual Sites Subject to Episodic Diversifying Selection

(2012) Ben Murrell et al.   PLoS Genetics

The ADAR protein family

(2012) Yiannis A Savva et al.   GENOME BIOLOGY

GeCo++: a C++ library for genomic features computation and annotation in the presence of variants

(2011) M. Cereda et al.   BIOINFORMATICS

ProtTest 3: fast selection of best-fit models of protein evolution

(2011) Diego Darriba et al.   BIOINFORMATICS

Accurate identification of A-to-I RNA editing in human by transcriptome sequencing

(2011) J. H. Bahn et al.   GENOME RESEARCH

An essential role of RNA editing enzyme ADAR1 in mouse skin

(2011) Rohit Sharma et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor

(2011) M. Doria et al.   JOURNAL OF GENERAL VIROLOGY

A Random Effects Branch-Site Model for Detecting Episodic Diversifying Selection

(2011) Sergei L. Kosakovsky Pond et al.   MOLECULAR BIOLOGY AND EVOLUTION

A high-resolution map of human evolutionary constraint using 29 mammals

(2011) Kerstin Lindblad-Toh et al.   NATURE

Zalpha-domains: At the intersection between RNA editing and innate immunity

(2011) Alekos Athanasiadis   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

ADAR1 is a novel multi targeted anti-HIV-1 cellular protein

(2011) Nabanita Biswas et al.   VIROLOGY

A Population Genetics-Phylogenetics Approach to Inferring Natural Selection in Coding Sequences

(2011) Daniel J. Wilson et al.   PLoS Genetics

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology

(2010) W. Delport et al.   BIOINFORMATICS

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1

(2010) J. Yeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenosine-to-inosine RNA editing shapes transcriptome diversity in primates

(2010) N. Paz-Yaacov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA editing: a driving force for adaptive evolution?

(2009) Willemijn M. Gommans et al.   BIOESSAYS

RNA granules: post-transcriptional and epigenetic modulators of gene expression

(2009) Paul Anderson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection

(2009) Margherita Doria et al.   NUCLEIC ACIDS RESEARCH

Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

(2009) Luis B. Barreiro et al.   PLoS Genetics

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

(2008) A. D. Johnson et al.   BIOINFORMATICS

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

(2008) A. J. Vilella et al.   GENOME RESEARCH

Double-Stranded RNA Adenosine Deaminases Enhance Expression of Human Immunodeficiency Virus Type 1 Proteins

(2008) A. Phuphuakrat et al.   JOURNAL OF VIROLOGY