Protein kinase C (PKC) as a drug target in chronic lymphocytic leukemia
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Protein kinase C (PKC) as a drug target in chronic lymphocytic leukemia
Authors
Keywords
CLL, B-CLL, FLT3, KIT, PDGFR, CSF1R, M-CSFR
Journal
MEDICAL ONCOLOGY
Volume 30, Issue 4, Pages -
Publisher
Springer Nature
Online
2013-10-30
DOI
10.1007/s12032-013-0757-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Protein Kinase C-β-Dependent Activation of NF-κB in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B Cells In Vivo
- (2013) Gloria Lutzny et al. CANCER CELL
- The tyrosine kinase CSK associates with FLT3 and c-Kit receptors and regulates downstream signaling
- (2013) Julhash U. Kazi et al. CELLULAR SIGNALLING
- Protein kinase C expression is deregulated in chronic lymphocytic leukemia
- (2013) Nuzhat N. Kabir et al. LEUKEMIA & LYMPHOMA
- Protein kinase C isoform expression in chronic lymphocytic leukemia: a potential target for therapy?
- (2013) O. Giles Best et al. LEUKEMIA & LYMPHOMA
- Deregulation of protein phosphatase expression in acute myeloid leukemia
- (2013) Nuzhat N. Kabir et al. MEDICAL ONCOLOGY
- Selective mutation in ATP-binding site reduces affinity of drug to the kinase: a possible mechanism of chemo-resistance
- (2013) Nuzhat N. Kabir et al. MEDICAL ONCOLOGY
- FLT3 mutations in patients with childhood acute lymphoblastic leukemia (ALL)
- (2013) Nuzhat N. Kabir et al. MEDICAL ONCOLOGY
- Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling
- (2013) Julhash U. Kazi et al. Molecular Oncology
- Src-Like Adaptor Protein (SLAP) Binds to the Receptor Tyrosine Kinase Flt3 and Modulates Receptor Stability and Downstream Signaling
- (2013) Julhash U. Kazi et al. PLoS One
- Chronic lymphocytic leukemia: a clinical and molecular heterogenous disease
- (2013) Ana E. Rodríguez-Vicente et al. Cancer Genetics
- Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3
- (2012) D.-C. Lin et al. BLOOD
- Suppressor of Cytokine Signaling 6 (SOCS6) Negatively Regulates Flt3 Signal Transduction through Direct Binding to Phosphorylated Tyrosines 591 and 919 of Flt3
- (2012) Julhash U. Kazi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia
- (2012) Julhash U. Kazi et al. Molecular Oncology
- Protein kinase C, an elusive therapeutic target?
- (2012) Daria Mochly-Rosen et al. NATURE REVIEWS DRUG DISCOVERY
- The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85
- (2011) Thomas Oellerich et al. EMBO JOURNAL
- Enzastaurin hydrochloride for lymphoma: reassessing the results of clinical trials in light of recent advances in the biology of B-cell malignancies
- (2011) Loic Ysebaert et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Comparative analysis of human and bovine protein kinases reveals unique relationship and functional diversity
- (2011) Nuzhat N. Kabir et al. GENETICS AND MOLECULAR BIOLOGY
- Protein-tyrosine Phosphatase DEP-1 Controls Receptor Tyrosine Kinase FLT3 Signaling
- (2011) Deepika Arora et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Role of Atypical Protein Kinase C in CSF-1-Dependent Erk Activation and Proliferation in Myeloid Progenitors and Macrophages
- (2011) Angel W. Lee PLoS One
- M-CSF Induces Monocyte Survival by Activating NF-κB p65 Phosphorylation at Ser276 via Protein Kinase C
- (2011) Yijie Wang et al. PLoS One
- Protein Kinase C: An Attractive Target for Cancer Therapy
- (2011) Barbara Marengo et al. Cancers
- PEP005 (ingenol mebutate) gel for the topical treatment of superficial basal cell carcinoma: Results of a randomized phase IIa trial
- (2010) Greg Siller et al. AUSTRALASIAN JOURNAL OF DERMATOLOGY
- Vascular endothelial growth factor stimulates protein kinase C II expression in chronic lymphocytic leukemia cells
- (2010) S. T. Abrams et al. BLOOD
- Role of Regulatory Domain Mutants of PKC Isoforms in c-fos Induction
- (2010) BULLETIN OF THE KOREAN CHEMICAL SOCIETY
- Subcellular Localization of Diacylglycerol-responsive Protein Kinase C Isoforms in HeLa Cells
- (2010) BULLETIN OF THE KOREAN CHEMICAL SOCIETY
- Novel Antileukemic Compound Ingenol 3-Angelate Inhibits T Cell Apoptosis by Activating Protein Kinase Cθ
- (2010) Wing-yiu Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Recruitment of PKC-βII to lipid rafts mediates apoptosis-resistance in chronic lymphocytic leukemia expressing ZAP-70
- (2009) C Meyer zum Büschenfelde et al. LEUKEMIA
- Enzastaurin
- (2008) Yi-Bin Chen et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Bioinformatic prediction and analysis of eukaryotic protein kinases in the rat genome
- (2008) Julhash U. Kazi et al. GENE
- Structural Basis of Protein Kinase C Isoform Function
- (2008) Susan F. Steinberg PHYSIOLOGICAL REVIEWS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started