Cyanobacteria from Terrestrial and Marine Sources Contain Apoptogens Able to Overcome Chemoresistance in Acute Myeloid Leukemia Cells

Cyanobacteria: potential candidates for drug discovery

(2013) Rakhi Bajpai Dixit et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

A phase 2 trial of azacitidine and gemtuzumab ozogamicin therapy in older patients with acute myeloid leukemia

(2013) S. Nand et al.   BLOOD

Genome Mining Expands the Chemical Diversity of the Cyanobactin Family to Include Highly Modified Linear Peptides

(2013) Niina Leikoski et al.   CHEMISTRY & BIOLOGY

Pediatric Relapsed or Refractory Leukemia: New Pharmacotherapeutic Developments and Future Directions

(2013) Keith J. August et al.   DRUGS

Phase II trial of clofarabine with topotecan, vinorelbine, and thiotepa in pediatric patients with relapsed or refractory acute leukemia

(2013) Neerav Shukla et al.   PEDIATRIC BLOOD & CANCER

Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells

(2013) Andrew M. Hau et al.   PLoS One

New Structural Variants of Aeruginosin Produced by the Toxic Bloom Forming Cyanobacterium Nodularia spumigena

(2013) David P. Fewer et al.   PLoS One

Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing

(2013) P. M. Shih et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyanobacteria and Cyanotoxins: From Impacts on Aquatic Ecosystems and Human Health to Anticarcinogenic Effects

(2013) Giliane Zanchett et al.   Toxins

Genome-derived insights into the biology of the hepatotoxic bloom-forming cyanobacterium Anabaena sp. strain 90

(2012) Hao Wang et al.   BMC GENOMICS

Azacitidine fails to eradicate leukemic stem/progenitor cell populations in patients with acute myeloid leukemia and myelodysplasia

(2012) C Craddock et al.   LEUKEMIA

Largazole: From discovery to broad-spectrum therapy

(2012) Jiyong Hong et al.   NATURAL PRODUCT REPORTS

Anabaenolysins, Novel Cytolytic Lipopeptides from Benthic Anabaena Cyanobacteria

(2012) Jouni Jokela et al.   PLoS One

Analysis of an Inactive Cyanobactin Biosynthetic Gene Cluster Leads to Discovery of New Natural Products from Strains of the Genus Microcystis

(2012) Niina Leikoski et al.   PLoS One

Cyanobacteria produce a high variety of hepatotoxic peptides in lichen symbiosis

(2012) U. Kaasalainen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Malyngamide 3 and Cocosamides A and B from the Marine CyanobacteriumLyngbya majusculafrom Cocos Lagoon, Guam

(2011) Sarath P. Gunasekera et al.   JOURNAL OF NATURAL PRODUCTS

Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia

(2011) E McCormack et al.   LEUKEMIA

Nostocyclopeptide-M1: A Potent, Nontoxic Inhibitor of the Hepatocyte Drug Transporters OATP1B3 and OATP1B1

(2011) Lars Herfindal et al.   MOLECULAR PHARMACEUTICS

A Novel Cyanobacterial Nostocyclopeptide is a Potent Antitoxin against Microcystins

(2010) Jouni Jokela  et al.   CHEMBIOCHEM

Phase IIB Trial of Oral Midostaurin (PKC412), the FMS-Like Tyrosine Kinase 3 Receptor (FLT3) and Multi-Targeted Kinase Inhibitor, in Patients With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome With Either Wild-Type or Mutated FLT3

(2010) Thomas Fischer et al.   JOURNAL OF CLINICAL ONCOLOGY

The apoptosis-inducing activity towards leukemia and lymphoma cells in a cyanobacterial culture collection is not associated with mouse bioassay toxicity

(2010) Linn Oftedal et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Marine Benthic Cyanobacteria Contain Apoptosis-Inducing Activity Synergizing with Daunorubicin to Kill Leukemia Cells, but not Cardiomyocytes

(2010) Linn Oftedal et al.   Marine Drugs

Cyanobacterial Cyclopeptides as Lead Compounds to Novel Targeted Cancer Drugs

(2010) Ioannis Sainis et al.   Marine Drugs

Do lichens domesticate photobionts like farmers domesticate crops? Evidence from a previously unrecognized lineage of filamentous cyanobacteria

(2009) Robert Lücking et al.   AMERICAN JOURNAL OF BOTANY

Highly Diverse Cyanobactins in Strains of the Genus Anabaena

(2009) N. Leikoski et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Acyloxymethyl Esterification of Nodularin-R and Microcystin-LA Produces Inactive Protoxins that Become Reactivated and Produce Apoptosis inside Intact Cells

(2009) Lars Herfindal et al.   JOURNAL OF MEDICINAL CHEMISTRY

Marine Benthic Diatoms Contain Compounds Able to Induce Leukemia Cell Death and Modulate Blood Platelet Activity

(2009) Siv Kristin Prestegard et al.   Marine Drugs

Microcystin Production in the Tripartite CyanolichenPeltigera leucophlebia

(2009) Ulla Kaasalainen et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Bisebromoamide, a Potent Cytotoxic Peptide from the Marine CyanobacteriumLyngbyasp.: Isolation, Stereostructure, and Biological Activity

(2009) Toshiaki Teruya et al.   ORGANIC LETTERS

Characterization of Organic Anion Transporting Polypeptide 1b2-null Mice: Essential Role in Hepatic Uptake/Toxicity of Phalloidin and Microcystin-LR

(2008) Hong Lu et al.   TOXICOLOGICAL SCIENCES

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY