Valproic acid induces differentiation and transient tumor regression, but spares leukemia-initiating activity in mouse models of APL

Revisiting the differentiation paradigm in acute promyelocytic leukemia

(2011) J. Ablain et al.   BLOOD

The Drug-Induced Degradation of Oncoproteins: An Unexpected Achilles' Heel of Cancer Cells?

(2011) Julien Ablain et al.   Cancer Discovery

Discovery of Novel Transcriptional and Epigenetic Targets in APL by Global ChIP Analyses: Emerging Opportunity and Challenge

(2010) Jan-Henrik Mikesch et al.   CANCER CELL

The deacetylase inhibitor LAQ824 induces notch signalling in haematopoietic progenitor cells

(2010) Kerstin Schwarz et al.   LEUKEMIA RESEARCH

Histone deacetylases and epigenetic therapies of hematological malignancies

(2010) Ciro Mercurio et al.   PHARMACOLOGICAL RESEARCH

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia

(2009) F. C. Guibal et al.   BLOOD

How I treat acute promyelocytic leukemia

(2009) M. S. Tallman et al.   BLOOD

Curing APL: Differentiation or Destruction?

(2009) Scott C. Kogan   CANCER CELL

Rational Combinations Using HDAC Inhibitors

(2009) M. Bots et al.   CLINICAL CANCER RESEARCH

PML–RARα initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors

(2009) S Wojiski et al.   LEUKEMIA

Acute promyelocytic leukemia: from highly fatal to highly curable

(2008) Z.-Y. Wang et al.   BLOOD

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

(2008) Rihab Nasr et al.   NATURE MEDICINE