Mass spectrometry-based ligand binding assays on adenosine A1 and A2A receptors

MS Binding Assays for the Three Monoamine Transporters Using the Triple Reuptake Inhibitor (1R,3S)-Indatraline as Native Marker

(2015) Stefanie H. Grimm et al.   ChemMedChem

Molecular mechanism of allosteric modulation at GPCRs: insight from a binding kinetics study at the human A1adenosine receptor

(2014) Dong Guo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Binding Kinetics of ZM241385 Derivatives at the Human Adenosine A2AReceptor

(2014) Dong Guo et al.   ChemMedChem

Drug-Target Residence Time-A Case for G Protein-Coupled Receptors

(2014) Dong Guo et al.   MEDICINAL RESEARCH REVIEWS

Novel adenosine A2A receptor ligands: A synthetic, functional and computational investigation of selected literature adenosine A2A receptor antagonists for extending into extracellular space

(2013) Manuela Jörg et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Adenosine receptors as drug targets — what are the challenges?

(2013) Jiang-Fan Chen et al.   NATURE REVIEWS DRUG DISCOVERY

Functional efficacy of adenosine A2A receptor agonists is positively correlated to their receptor residence time

(2012) Dong Guo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Synthesis, molecular structure, NMR spectroscopic and computational analysis of a selective adenosine A2A antagonist, ZM 241385

(2012) Manuela Jörg et al.   STRUCTURAL CHEMISTRY

Development and validation of a rapid LC-ESI-MS/MS method for quantification of fluoxetine and its application to MS binding assays

(2011) Marielle Hess et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Ligand binding assays at equilibrium: validation and interpretation

(2010) Edward C. Hulme et al.   BRITISH JOURNAL OF PHARMACOLOGY

Critical topics in ensuring data quality in bioanalytical LC–MS method development

(2010) Daniel E Mulvana   Bioanalysis

Adenosine A2AReceptor-Antagonist/Dopamine D2Receptor-Agonist Bivalent Ligands as Pharmacological Tools to Detect A2A-D2Receptor Heteromers

(2009) Aroa Soriano et al.   JOURNAL OF MEDICINAL CHEMISTRY