Regulation of osteoclastogenesis through Tim-3: possible involvement of the Tim-3/galectin-9 system in the modulation of inflammatory bone destruction

Impaired Expression of Tim-3 on Th17 and Th1 Cells in Psoriasis

(2013) Y Kanai et al.   ACTA DERMATO-VENEREOLOGICA

Using EAE to better understand principles of immune function and autoimmune pathology

(2013) Manu Rangachari et al.   JOURNAL OF AUTOIMMUNITY

Hanging in the balance: endogenous anti-inflammatory mechanisms in tissue repair and fibrosis

(2012) Amiram Ariel et al.   JOURNAL OF PATHOLOGY

Nordihydroguaiaretic acid inhibition of NFATc1 suppresses osteoclastogenesis and arthritis bone destruction in rats

(2012) Yin-Ji Li et al.   LABORATORY INVESTIGATION

Tumor immunity times out: TIM-3 and HMGB1

(2012) Daolin Tang et al.   NATURE IMMUNOLOGY

Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

(2012) Shigeki Chiba et al.   NATURE IMMUNOLOGY

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

(2012) Nunzio Bottini et al.   Nature Reviews Rheumatology

The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo

(2011) Akiko Kukita et al.   ARTHRITIS AND RHEUMATISM

Inflammation: a role for NR4A orphan nuclear receptors?

(2011) Jason P. McMorrow et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Phosphotyrosine-Dependent Coupling of Tim-3 to T-Cell Receptor Signaling Pathways

(2011) J. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis

(2011) F. G. Goh et al.   RHEUMATOLOGY

Emerging Tim-3 functions in antimicrobial and tumor immunity

(2011) Kaori Sakuishi et al.   TRENDS IN IMMUNOLOGY

Tim3 binding to galectin-9 stimulates antimicrobial immunity

(2010) Pushpa Jayaraman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Galectin-9 ameliorates immune complex-induced arthritis by regulating FcγR expression on macrophages

(2009) Tomohiro Arikawa et al.   CLINICAL IMMUNOLOGY

TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines

(2009) William D. Hastings et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T-cell growth, cell surface organization, and the galectin-glycoprotein lattice

(2009) Ani Grigorian et al.   IMMUNOLOGICAL REVIEWS

A New Inflammatory Cytokine on the Block: Re-thinking Periodontal Disease and the Th1/Th2 Paradigm in the Context of Th17 Cells and IL-17

(2009) S.L. Gaffen et al.   JOURNAL OF DENTAL RESEARCH

Roles of galectins in infection

(2009) Gerardo R. Vasta   NATURE REVIEWS MICROBIOLOGY

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis

(2008) Masako Seki et al.   CLINICAL IMMUNOLOGY

Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice

(2008) Atsuya Nobumoto et al.   CLINICAL IMMUNOLOGY

A possible suppressive role of galectin-3 in upregulated osteoclastogenesis accompanying adjuvant-induced arthritis in rats

(2008) Yin-Ji Li et al.   LABORATORY INVESTIGATION

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE