PI3K p110γ overexpression in idiopathic pulmonary fibrosis lung tissue and fibroblast cells: in vitro effects of its inhibition

FAK and WNT Signaling: The Meeting of Two Pathways in Cancer and Development

(2012) Yuri Fonar et al.   Anti-Cancer Agents in Medicinal Chemistry

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

(2011) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolismin vivo

(2011) Greg C. Smith et al.   BIOCHEMICAL JOURNAL

Resveratrol inhibits transforming growth factor-β–induced proliferation and differentiation of ex vivo human lung fibroblasts into myofibroblasts through ERK/Akt inhibition and PTEN restoration

(2011) Evelina Fagone et al.   EXPERIMENTAL LUNG RESEARCH

PI3K class IB controls the cell cycle checkpoint promoting cell proliferation in hepatocellular carcinoma

(2011) Francesco Dituri et al.   INTERNATIONAL JOURNAL OF CANCER

Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44

(2011) Yuejuan Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phosphatidylinositol 3-Kinase Isoform-Specific Effects in Airway Mesenchymal Cell Function

(2011) L. M. Moir et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Comparative Proteomic Analysis of Lung Tissue from Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lung Transplant Donor Lungs

(2011) Martina Korfei et al.   JOURNAL OF PROTEOME RESEARCH

A Sensitized RNA Interference Screen Identifies a Novel Role for the PI3K p110  Isoform in Medulloblastoma Cell Proliferation and Chemoresistance

(2011) A. S. Guerreiro et al.   MOLECULAR CANCER RESEARCH

Inhibition of PI3K Prevents the Proliferation and Differentiation of Human Lung Fibroblasts into Myofibroblasts: The Role of Class I P110 Isoforms

(2011) Enrico Conte et al.   PLoS One

Pathologic Caveolin-1 Regulation of PTEN in Idiopathic Pulmonary Fibrosis

(2010) Hong Xia et al.   AMERICAN JOURNAL OF PATHOLOGY

Targeting Phosphoinositide-3-Kinase-δ with Theophylline Reverses Corticosteroid Insensitivity in Chronic Obstructive Pulmonary Disease

(2010) Yasuo To et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A phosphoinositide 3-kinase-γ inhibitor, AS605240 prevents bleomycin-induced pulmonary fibrosis in rats

(2010) Xin Wei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Key Role of Phosphoinositide 3-Kinase Class IB in Pancreatic Cancer

(2010) C. E. Edling et al.   CLINICAL CANCER RESEARCH

Idiopathic pulmonary fibrosis: a disease with similarities and links to cancer biology

(2010) C. Vancheri et al.   EUROPEAN RESPIRATORY JOURNAL

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phosphatidylinositol 3-kinase isoforms as targets in respiratory disease

(2010) John A. Marwick et al.   Therapeutic Advances in Respiratory Disease

Transcription Factor GATA-6 Is Expressed in Quiescent Myofibroblasts in Idiopathic Pulmonary Fibrosis

(2009) Outi Leppäranta et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Proliferative activity in fibrosing lung diseases: a comparative study of Ki-67 immunoreactivity in diffuse alveolar damage, bronchiolitis obliterans–organizing pneumonia, and usual interstitial pneumonia

(2009) Ola El-Zammar et al.   HUMAN PATHOLOGY

The PTEN–PI3K pathway: of feedbacks and cross-talks

(2008) A Carracedo et al.   ONCOGENE