Recent advances in microfluidic techniques for single-cell biophysical characterization

A label-free DC impedance-based microcytometer for circulating rare cancer cell counting

(2013) Hyoungseon Choi et al.   LAB ON A CHIP

Microfluidics-Based Assessment of Cell Deformability

(2012) Andrea Adamo et al.   ANALYTICAL CHEMISTRY

Deformation measurement of individual cells in large populations using a single-cell microchamber array chip

(2012) I. Doh et al.   APPLIED PHYSICS LETTERS

A tapered channel microfluidic device for comprehensive cell adhesion analysis, using measurements of detachment kinetics and shear stress-dependent motion

(2012) Peter Rupprecht et al.   Biomicrofluidics

Dielectrophoretic capture voltage spectrum for measurement of dielectric properties and separation of cancer cells

(2012) Liqun Wu et al.   Biomicrofluidics

Microfluidic characterization of specific membrane capacitance and cytoplasm conductivity of singlecells

(2012) Yi Zheng et al.   BIOSENSORS & BIOELECTRONICS

Real-time control of a microfluidic channel for size-independent deformability cytometry

(2012) Guofeng Guan et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Microfluidic cell volume sensor with tunable sensitivity

(2012) Jason Riordon et al.   LAB ON A CHIP

Characterization of a novel impedance cytometer design and its integration with lateral focusing by dielectrophoresis

(2012) Guillaume Mernier et al.   LAB ON A CHIP

Microfluidic biomechanical assay for red blood cells parasitized by Plasmodium falciparum

(2012) Quan Guo et al.   LAB ON A CHIP

Elastomeric microposts integrated into microfluidics for flow-mediated endothelial mechanotransduction analysis

(2012) Raymond H. W. Lam et al.   LAB ON A CHIP

High-throughput biophysical measurement of human red blood cells

(2012) Yi Zheng et al.   LAB ON A CHIP

Microfluidic approaches for cancer cell detection, characterization, and separation

(2012) Jian Chen et al.   LAB ON A CHIP

Label-free electrophysiological cytometry for stem cell-derived cardiomyocyte clusters

(2012) Frank B. Myers et al.   LAB ON A CHIP

Mechanics: The forces of cancer

(2012) Erika Jonietz   NATURE

Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy

(2012) Alon Greenbaum et al.   NATURE METHODS

Hydrodynamic stretching of single cells for large population mechanical phenotyping

(2012) D. R. Gossett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput single-microparticle imaging flow analyzer

(2012) K. Goda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microfluidic Lysis of Human Blood for Leukocyte Analysis Using Single Cell Impedance Cytometry

(2011) Xiaojun Han et al.   ANALYTICAL CHEMISTRY

Electroporation Dependence on Cell Size: Optical Tweezers Study

(2011) Brian E. Henslee et al.   ANALYTICAL CHEMISTRY

Optofluidic Tomography on a Chip

(2011) Serhan O. Isikman et al.   APPLIED PHYSICS LETTERS

A microfluidic device for simultaneous electrical and mechanical measurements on single cells

(2011) Jian Chen et al.   Biomicrofluidics

Chip-based impedance measurement on single cells for monitoring sub-toxic effects on cell membranes

(2011) Christian M. Kurz et al.   BIOSENSORS & BIOELECTRONICS

Impaired Red Blood Cell Deformability in Patients with Coronary Artery Disease and Diabetes Mellitus

(2011) S. Keymel et al.   HORMONE AND METABOLIC RESEARCH

(Micro)managing the mechanical microenvironment

(2011) Christopher Moraes et al.   Integrative Biology

Electrodeformation for single cell mechanical characterization

(2011) Jian Chen et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Integrated systems for rapid point of care (PoC) blood cell analysis

(2011) Cees van Berkel et al.   LAB ON A CHIP

Single-cell electrical lysis of erythrocytes detects deficiencies in the cytoskeletal protein network

(2011) Ning Bao et al.   LAB ON A CHIP

Microfluidic approaches for gene delivery and gene therapy

(2011) Jungkyu Kim et al.   LAB ON A CHIP

A microfabricated deformability-based flow cytometer with application to malaria

(2011) Hansen Bow et al.   LAB ON A CHIP

Classification of cell types using a microfluidic device for mechanical and electrical measurement on single cells

(2011) Jian Chen et al.   LAB ON A CHIP

Simultaneous high speed optical and impedance analysis of single particles with a microfluidic cytometer

(2011) David Barat et al.   LAB ON A CHIP

Microfluidic devices for mechanical characterisation of single cells in suspension

(2011) Yi Zheng et al.   Micro & Nano Letters

Shape and Biomechanical Characteristics of Human Red Blood Cells in Health and Disease

(2011) Monica Diez-Silva et al.   MRS BULLETIN

Multiscale approach to link red blood cell dynamics, shear viscosity, and ATP release

(2011) A. M. Forsyth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measuring single-cell density

(2011) W. H. Grover et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Label-free cell separation and sorting in microfluidic systems

(2010) Daniel R. Gossett et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Single Cell Impedance Cytometry for Identification and Counting of CD4 T-Cells in Human Blood Using Impedance Labels

(2010) David Holmes et al.   ANALYTICAL CHEMISTRY

Sickle Cell Biomechanics

(2010) Gilda A. Barabino et al.   Annual Review of Biomedical Engineering

Microfluidic Platforms for Single-Cell Analysis

(2010) Richard N. Zare et al.   Annual Review of Biomedical Engineering

Cell types can be distinguished by measuring their viscoelastic recovery times using a micro-fluidic device

(2010) Guansheng Du et al.   BIOMEDICAL MICRODEVICES

Measurement of single-cell adhesion strength using a microfluidic assay

(2010) Kevin V. Christ et al.   BIOMEDICAL MICRODEVICES

Review Article—Dielectrophoresis: Status of the theory, technology, and applications

(2010) Ronald Pethig   Biomicrofluidics

Microfluidic impedance-based flow cytometry

(2010) Karen C. Cheung et al.   CYTOMETRY PART A

Fabrication of a microfluidic Ag/AgCl reference electrode and its application for portable and disposable electrochemical microchips

(2010) Jianhua Zhou et al.   ELECTROPHORESIS

Microfluidic electroporation of tumor and blood cells: observation of nucleus expansion and implications on selective analysis and purging of circulating tumor cells

(2010) Ning Bao et al.   Integrative Biology

Electrical classification of single red blood cell deformability in high-shear microchannel flows

(2010) Yoichi Katsumoto et al.   INTERNATIONAL JOURNAL OF HEAT AND FLUID FLOW

Optofluidic chip for single cell trapping and stretching fabricated by a femtosecond laser

(2010) Francesca Bragheri et al.   Journal of Biophotonics

Circulating Tumor Cells: Detection Methods and Potential Clinical Application in Breast Cancer

(2010) Seung Il Kim et al.   Journal of Breast Cancer

Mechanical properties of mammalian cells in suspension measured by electro-deformation

(2010) Luke A MacQueen et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Micro-impedance cytometry for detection and analysis of micron-sized particles and bacteria

(2010) Catia Bernabini et al.   LAB ON A CHIP

Single-cell microfluidic impedance cytometry: a review

(2010) Tao Sun et al.   Microfluidics and Nanofluidics

Microfluidics cell electroporation

(2010) Saeid Movahed et al.   Microfluidics and Nanofluidics

The dynamic behavior of chemically “stiffened” red blood cells in microchannel flows

(2010) Alison M. Forsyth et al.   MICROVASCULAR RESEARCH

Probing Cellular Traction Forces by Micropillar Arrays: Contribution of Substrate Warping to Pillar Deflection

(2010) Ingmar Schoen et al.   NANO LETTERS

Using buoyant mass to measure the growth of single cells

(2010) Michel Godin et al.   NATURE METHODS

Are biomechanical changes necessary for tumour progression?

(2010) Anatol Fritsch et al.   Nature Physics

Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution

(2010) Waheb Bishara et al.   OPTICS EXPRESS

Femtosecond laser fabricated monolithic chip for optical trapping and stretching of single cells

(2010) N. Bellini et al.   OPTICS EXPRESS

Quantification of the adhesion strength of fibroblast cells on ethylene glycol terminated self-assembled monolayers by a microfluidic shear force assay

(2010) Christof Christophis et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Microfabricated Reference Electrodes and their Biosensing Applications

(2010) M. Waleed Shinwari et al.   SENSORS

Review of cell and particle trapping in microfluidic systems

(2009) J. Nilsson et al.   ANALYTICA CHIMICA ACTA

Microengineered Platforms for Cell Mechanobiology

(2009) Deok-Ho Kim et al.   Annual Review of Biomedical Engineering

Extensional flow-based assessment of red blood cell deformability using hyperbolic converging microchannel

(2009) Sung S. Lee et al.   BIOMEDICAL MICRODEVICES

Microfluidics as a functional tool for cell mechanics

(2009) Siva A. Vanapalli et al.   Biomicrofluidics

Oral Cancer Diagnosis by Mechanical Phenotyping

(2009) T. W. Remmerbach et al.   CANCER RESEARCH

Deformability limits ofPlasmodium falciparum-infected red blood cells

(2009) Thurston Herricks et al.   CELLULAR MICROBIOLOGY

Red blood cell quantification microfluidic chip using polyelectrolytic gel electrodes

(2009) Kwang Bok Kim et al.   ELECTROPHORESIS

Dielectric characterization of complete mononuclear and polymorphonuclear blood cell subpopulations for label-free discrimination

(2009) Daynene M. Vykoukal et al.   Integrative Biology

Whole-Cell Impedance Analysis for Highly and Poorly Metastatic Cancer Cells

(2009) Younghak Cho et al.   JOURNAL OF MICROELECTROMECHANICAL SYSTEMS

Leukocyte analysis and differentiation using high speed microfluidic single cell impedance cytometry

(2009) David Holmes et al.   LAB ON A CHIP

Flexible Microfluidic Device for Mechanical Property Characterization of Soft Viscoelastic Solids Such as Bacterial Biofilms

(2009) Danial N. Hohne et al.   LANGMUIR

Continuous differential impedance spectroscopy of single cells

(2009) Daniele Malleo et al.   Microfluidics and Nanofluidics

The regulatory role of cell mechanics for migration of differentiating myeloid cells

(2009) F. Lautenschlager et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomechanical analysis of cancerous and normal cells based on bulge generation in a microfluidic device

(2008) Yu Chang Kim et al.   ANALYST

Microfluidic Electroporative Flow Cytometry for Studying Single-Cell Biomechanics

(2008) Ning Bao et al.   ANALYTICAL CHEMISTRY

Effects on capacitance by overexpression of membrane proteins

(2008) D. Zimmermann et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Deformability study of breast cancer cells using microfluidics

(2008) H. W. Hou et al.   BIOMEDICAL MICRODEVICES

On-chip non-invasive and label-free cell discrimination by impedance spectroscopy

(2008) G. Schade-Kampmann et al.   CELL PROLIFERATION

Analyzing cell mechanics in hematologic diseases with microfluidic biophysical flow cytometry

(2008) Michael J. Rosenbluth et al.   LAB ON A CHIP

Hereditary spherocytosis

(2008) Silverio Perrotta et al.   LANCET

Lensless high-resolution on-chip optofluidic microscopes for Caenorhabditis elegans and cell imaging

(2008) X. Cui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Refractive index maps and membrane dynamics of human red blood cells parasitized by Plasmodium falciparum

(2008) Y. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A cell delivery and pre-positioning system utilizing microfluidic devices for dual-beam optical trap-and-stretch

(2008) Chia-Wei Lai et al.   SENSORS AND ACTUATORS B-CHEMICAL