A Single Amino Acid Substitution in the Novel H7N9 Influenza A Virus NS1 Protein Increases CPSF30 Binding and Virulence

The PB2 E627K mutation contributes to the high polymerase activity and enhanced replication of H7N9 influenza virus

(2014) H. Zhang et al.   JOURNAL OF GENERAL VIROLOGY

Amino Acid Substitutions in Polymerase Basic Protein 2 Gene Contribute to the Pathogenicity of the Novel A/H7N9 Influenza Virus in Mammalian Hosts

(2014) C. K. P. Mok et al.   JOURNAL OF VIROLOGY

H7N9 influenza viruses interact preferentially with  2,3-linked sialic acids and bind weakly to  2,6-linked sialic acids

(2013) I. Ramos et al.   JOURNAL OF GENERAL VIROLOGY

Virulence-Affecting Amino Acid Changes in the PA Protein of H7N9 Influenza A Viruses

(2013) S. Yamayoshi et al.   JOURNAL OF VIROLOGY

Receptor binding by an H7N9 influenza virus from humans

(2013) Xiaoli Xiong et al.   NATURE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preferential Recognition of Avian-Like Receptors in Human Influenza A H7N9 Viruses

(2013) R. Xu et al.   SCIENCE

Structures and Receptor Binding of Hemagglutinins from Human-Infecting H7N9 Influenza Viruses

(2013) Y. Shi et al.   SCIENCE

Influenza A/Hong Kong/156/1997(H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG-I and CPSF30

(2013) Samar K Dankar et al.   Virology Journal

The Novel Human Influenza A(H7N9) Virus Is Naturally Adapted to Efficient Growth in Human Lung Tissue

(2013) J. Knepper et al.   mBio

Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility

(2013) Rong Hai et al.   Nature Communications

Multifunctional Adaptive NS1 Mutations Are Selected upon Human Influenza Virus Evolution in the Mouse

(2012) Nicole E. Forbes et al.   PLoS One

Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein

(2012) Ricardo Rajsbaum et al.   PLoS Pathogens

The Virulence of 1997 H5N1 Influenza Viruses in the Mouse Model Is Increased by Correcting a Defect in Their NS1 Proteins

(2011) A. Spesock et al.   JOURNAL OF VIROLOGY

Influenza A viruses: new research developments

(2011) Rafael A. Medina et al.   NATURE REVIEWS MICROBIOLOGY

Genomic and Protein Structural Maps of Adaptive Evolution of Human Influenza A Virus to Increased Virulence in the Mouse

(2011) Jihui Ping et al.   PLoS One

Glycine 184 in Nonstructural Protein NS1 Determines the Virulence of Influenza A Virus Strain PR8 without Affecting the Host Interferon Response

(2010) S. Steidle et al.   JOURNAL OF VIROLOGY

Inefficient Control of Host Gene Expression by the 2009 Pandemic H1N1 Influenza A Virus NS1 Protein

(2010) B. G. Hale et al.   JOURNAL OF VIROLOGY

Association of RIG-I with innate immunity of ducks to influenza

(2010) M. R. W. Barber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influenza A virus strains that circulate in humans differ in the ability of their NS1 proteins to block the activation of IRF3 and interferon-β transcription

(2010) Rei-Lin Kuo et al.   VIROLOGY

Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

(2009) Michaela Ulrike Gack et al.   Cell Host & Microbe

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY

Influenza B Virus NS1-Truncated Mutants: Live-Attenuated Vaccine Approach

(2008) R. Hai et al.   JOURNAL OF VIROLOGY

Influenza A Virus Polymerase Is an Integral Component of the CPSF30-NS1A Protein Complex in Infected Cells

(2008) R.-L. Kuo et al.   JOURNAL OF VIROLOGY

Structural basis for suppression of a host antiviral response by influenza A virus

(2008) K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA