Hydrophobic and Charged Residues in the C-Terminal Arm of Hepatitis C Virus RNA-Dependent RNA Polymerase Regulate Initiation and Elongation

The Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active Site

(2014) L. Vives-Adrian et al.   JOURNAL OF VIROLOGY

Structural and Regulatory Elements of HCV NS5B Polymerase – β-Loop and C-Terminal Tail – Are Required for Activity of Allosteric Thumb Site II Inhibitors

(2014) Sarah E. Boyce et al.   PLoS One

Structure of a VP1-VP3 Complex Suggests How Birnaviruses Package the VP1 Polymerase

(2013) M. W. Bahar et al.   JOURNAL OF VIROLOGY

Conformational Flexibility of the Dengue Virus RNA-Dependent RNA Polymerase Revealed by a Complex with an Inhibitor

(2013) C. G. Noble et al.   JOURNAL OF VIROLOGY

Assembly, Purification, and Pre-steady-state Kinetic Analysis of Active RNA-dependent RNA Polymerase Elongation Complex

(2012) Zhinan Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular basis for RNA polymerization by Qβ replicase

(2012) Daijiro Takeshita et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin

(2012) Intekhab Alam et al.   VIROLOGY

Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus  6 from De Novo Initiation to Elongation

(2011) S. Wright et al.   JOURNAL OF VIROLOGY

Further Insights into the Roles of GTP and the C Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis

(2010) Déborah Harrus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase

(2010) P. Gong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus Polymerase

(2008) Sreedhar Chinnaswamy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Coxsackievirus B3 3Dpol Highlights the Functional Importance of Residue 5 in Picornavirus Polymerases

(2008) G. Campagnola et al.   JOURNAL OF VIROLOGY