Epstein-Barr Virus Utilizes Ikaros in Regulating Its Latent-Lytic Switch in B Cells

The B-Cell-Specific Transcription Factor and Master Regulator Pax5 Promotes Epstein-Barr Virus Latency by Negatively Regulating the Viral Immediate Early Protein BZLF1

(2013) R. M. Raver et al.   JOURNAL OF VIROLOGY

Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros

(2013) Hilde Schjerven et al.   NATURE IMMUNOLOGY

Regulatory Phosphorylation of Ikaros by Bruton's Tyrosine Kinase

(2013) Hong Ma et al.   PLoS One

Regulation of host gene expression by HIV-1 TAR microRNAs

(2013) Dominique L Ouellet et al.   Retrovirology

EBF1 acts as a powerful repressor of Blimp-1 gene expression in immature B cells

(2012) Hidehiko Kikuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

FoxO1 induces Ikaros splicing to promote immunoglobulin gene recombination

(2012) Alabbas Alkhatib et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lytic Epstein-Barr virus infection in epithelial cells but not in B-lymphocytes is dependent on Blimp1

(2012) M. Buettner et al.   JOURNAL OF GENERAL VIROLOGY

Genome-Wide Analysis of Epstein-Barr Virus Rta DNA Binding

(2012) A. M. F. Heilmann et al.   JOURNAL OF VIROLOGY

Viral Genome Methylation Differentially Affects the Ability of BZLF1 versus BRLF1 To Activate Epstein-Barr Virus Lytic Gene Expression and Viral Replication

(2012) C. K. Wille et al.   JOURNAL OF VIROLOGY

Different Patterns of Epstein-Barr Virus Latency in Endemic Burkitt Lymphoma (BL) Lead to Distinct Variants within the BL-Associated Gene Expression Signature

(2012) G. L. Kelly et al.   JOURNAL OF VIROLOGY

B-lineage transcription factors and cooperating gene lesions required for leukemia development

(2012) E Tijchon et al.   LEUKEMIA

IKAROS Deletions Dictate a Unique Gene Expression Signature in Patients with Adult B-Cell Acute Lymphoblastic Leukemia

(2012) Ilaria Iacobucci et al.   PLoS One

Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros

(2012) F. M. Uckun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BZLF1 Governs CpG-Methylated Chromatin of Epstein-Barr Virus Reversing Epigenetic Repression

(2012) Anne Woellmer et al.   PLoS Pathogens

The B-Cell Specific Transcription Factor, Oct-2, Promotes Epstein-Barr Virus Latency by Inhibiting the Viral Immediate-Early Protein, BZLF1

(2012) Amanda R. Robinson et al.   PLoS Pathogens

Ikaros is degraded by proteasome-dependent mechanism in the early phase of apoptosis induction

(2011) Li-Cai He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Down-regulation of BLIMP1  by the EBV oncogene, LMP-1, disrupts the plasma cell differentiation program and prevents viral replication in B cells: implications for the pathogenesis of EBV-associated B-cell lymphomas

(2011) K. Vrzalikova et al.   BLOOD

Alternate pathways for Bcl6-mediated regulation of B cell to plasma cell differentiation

(2011) Jukka Alinikula et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transforming Growth Factor  -Induced Reactivation of Epstein-Barr Virus Involves Multiple Smad-Binding Elements Cooperatively Activating Expression of the Latent-Lytic Switch BZLF1 Gene

(2011) T. Iempridee et al.   JOURNAL OF VIROLOGY

The ZIIR Element of the Epstein-Barr Virus BZLF1 Promoter Plays a Central Role in Establishment and Maintenance of Viral Latency

(2011) X. Yu et al.   JOURNAL OF VIROLOGY

Cellular Transcription Factor Oct-1 Interacts with the Epstein-Barr Virus BRLF1 Protein To Promote Disruption of Viral Latency

(2011) A. R. Robinson et al.   JOURNAL OF VIROLOGY

The Epstein-Barr Virus BRRF1 Protein, Na, Induces Lytic Infection in a TRAF2- and p53-Dependent Manner

(2011) S. R. Hagemeier et al.   JOURNAL OF VIROLOGY

Ikaros, CK2 kinase, and the road to leukemia

(2011) Sinisa Dovat et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)

(2011) Konstantinos J Mavrakis et al.   NATURE GENETICS

Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation

(2011) Stefania Bottardi et al.   NUCLEIC ACIDS RESEARCH

Awakening lineage potential by Ikaros-mediated transcriptional priming

(2010) Toshimi Yoshida et al.   CURRENT OPINION IN IMMUNOLOGY

Ikaros in immune receptor signaling, lymphocyte differentiation, and function

(2010) Matthias Merkenschlager   FEBS LETTERS

Epstein-Barr Virus LF2 Protein Regulates Viral Replication by Altering Rta Subcellular Localization

(2010) A. M. F. Heilmann et al.   JOURNAL OF VIROLOGY

Either ZEB1 or ZEB2/SIP1 Can Play a Central Role in Regulating the Epstein-Barr Virus Latent-Lytic Switch in a Cell-Type-Specific Manner

(2010) A. L. Ellis et al.   JOURNAL OF VIROLOGY

Ikaros and Aiolos Inhibit Pre-B-Cell Proliferation by Directly Suppressing c-Myc Expression

(2010) S. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

Development of B-lineage Predominant Lentiviral Vectors for Use in Genetic Therapies for B Cell Disorders

(2010) Blythe D Sather et al.   MOLECULAR THERAPY

MCAF1 and synergistic activation of the transcription of Epstein–Barr virus lytic genes by Rta and Zta

(2010) Li-Kwan Chang et al.   NUCLEIC ACIDS RESEARCH

The Pathogenesis of Pituitary Tumors

(2009) Sylvia L. Asa et al.   Annual Review of Pathology-Mechanisms of Disease

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization

(2009) M. Jourdan et al.   BLOOD

Notch1, Notch2, and Epstein-Barr virus-encoded nuclear antigen 2 signaling differentially affects proliferation and survival of Epstein-Barr virus-infected B cells

(2009) H. Kohlhof et al.   BLOOD

Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP)

(2009) I. Iacobucci et al.   BLOOD

Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing

(2009) J.-H. Kim et al.   GENOME RESEARCH

Self-Renewal of the Long-Term Reconstituting Subset of Hematopoietic Stem Cells is Regulated by Ikaros

(2009) Peter Papathanasiou et al.   STEM CELLS

Epstein-Barr virus latent membrane protein 2A exploits Notch1 to alter B-cell identity in vivo

(2008) L. J. Anderson et al.   BLOOD

Recruitment of Ikaros to Pericentromeric Heterochromatin Is Regulated by Phosphorylation

(2008) Zafer Gurel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ikaros Directly Represses the Notch Target GeneHes1in a Leukemia T Cell Line

(2008) Katie L. Kathrein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the ERK signal transduction pathway by Epstein-Barr virus immediate-early protein Rta

(2008) Y.-H. Lee et al.   JOURNAL OF GENERAL VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus Transactivator RTA Promotes Degradation of the Repressors To Regulate Viral Lytic Replication

(2008) Z. Yang et al.   JOURNAL OF VIROLOGY

Ikaros Represses the Transcriptional Response to Notch Signaling in T-Cell Development

(2008) E. Kleinmann et al.   MOLECULAR AND CELLULAR BIOLOGY

Epstein–Barr virus growth/latency III program alters cellular microRNA expression

(2008) Jennifer E. Cameron et al.   VIROLOGY