Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros

Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates

(2012) L. Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ikaros, CK2 kinase, and the road to leukemia

(2011) Sinisa Dovat et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis

(2011) Jiangwen Zhang et al.   NATURE IMMUNOLOGY

Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation

(2011) Stefania Bottardi et al.   NUCLEIC ACIDS RESEARCH

Awakening lineage potential by Ikaros-mediated transcriptional priming

(2010) Toshimi Yoshida et al.   CURRENT OPINION IN IMMUNOLOGY

Spleen tyrosine kinase as a molecular target for treatment of leukemias and lymphomas

(2010) Fatih M Uckun et al.   Expert Review of Anticancer Therapy

Ikaros in immune receptor signaling, lymphocyte differentiation, and function

(2010) Matthias Merkenschlager   FEBS LETTERS

Ikaros and Aiolos Inhibit Pre-B-Cell Proliferation by Directly Suppressing c-Myc Expression

(2010) S. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress

(2010) F. M. Uckun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Syk is a dual-specificity kinase that self-regulates the signal output from the B-cell antigen receptor

(2010) B. Heizmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational rearrangements upon Syk auto-phosphorylation

(2009) Ernesto Arias-Palomo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Polo-like-kinase 1 (PLK1) as a molecular target to overcome SYK-mediated resistance of B-lineage acute lymphoblastic leukaemia cells to oxidative stress

(2009) Fatih M. Uckun et al.   BRITISH JOURNAL OF HAEMATOLOGY

Ikaros Stability and Pericentromeric Localization Are Regulated by Protein Phosphatase 1

(2009) Marcela Popescu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induced-fit docking studies of the active and inactive states of protein tyrosine kinases

(2009) Haizhen Zhong et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Deletion ofIKZF1and Prognosis in Acute Lymphoblastic Leukemia

(2009) Charles G. Mullighan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular Mechanism of the Syk Activation Switch

(2008) Emily Tsang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recruitment of Ikaros to Pericentromeric Heterochromatin Is Regulated by Phosphorylation

(2008) Zafer Gurel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY