Topical Herpes Simplex Virus 2 (HSV-2) Vaccination with Human Papillomavirus Vectors Expressing gB/gD Ectodomains Induces Genital-Tissue-Resident Memory CD8+T Cells and Reduces Genital Disease and Viral Shedding after HSV-2 Challenge

Better Neutralization of Herpes Simplex Virus Type 1 (HSV-1) Than HSV-2 by Antibody From Recipients of GlaxoSmithKline HSV-2 Glycoprotein D2 Subunit Vaccine

(2014) Sita Awasthi et al.   JOURNAL OF INFECTIOUS DISEASES

Preferential infection of human Ad5-specific CD4 T cells by HIV in Ad5 naturally exposed and recombinant Ad5-HIV vaccinated individuals

(2014) Haitao Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct resident and recirculating memory T cell subsets in non-lymphoid tissues

(2013) Francis R Carbone et al.   CURRENT OPINION IN IMMUNOLOGY

Seroprevalence of Herpes Simplex Virus Types 1 and 2--United States, 1999-2010

(2013) H. Bradley et al.   JOURNAL OF INFECTIOUS DISEASES

An Adjuvanted Herpes Simplex Virus 2 Subunit Vaccine Elicits a T Cell Response in Mice and Is an Effective Therapeutic Vaccine in Guinea Pigs

(2013) M. Skoberne et al.   JOURNAL OF VIROLOGY

Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection

(2013) Jia Zhu et al.   NATURE

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

A Novel DNA Vaccine Technology Conveying Protection against a Lethal Herpes Simplex Viral Challenge in Mice

(2013) Julie L. Dutton et al.   PLoS One

T-cell immunity to human alphaherpesviruses

(2013) Werner JD Ouwendijk et al.   Current Opinion in Virology

Rapid localized spread and immunologic containment define Herpes simplex virus-2 reactivation in the human genital tract

(2013) Joshua T Schiffer et al.   eLife

Intravaginal immunization with HPV vectors induces tissue-resident CD8+ T cell responses

(2012) Nicolas Çuburu et al.   JOURNAL OF CLINICAL INVESTIGATION

Vaxfectin-adjuvanted plasmid DNA vaccine improves protection and immunogenicity in a murine model of genital herpes infection

(2012) M. Shlapobersky et al.   JOURNAL OF GENERAL VIROLOGY

A Herpes Simplex Virus 2 Glycoprotein D Mutant Generated by Bacterial Artificial Chromosome Mutagenesis Is Severely Impaired for Infecting Neuronal Cells and Infects Only Vero Cells Expressing Exogenous HVEM

(2012) K. Wang et al.   JOURNAL OF VIROLOGY

STAT4 Regulates Antiviral Gamma Interferon Responses and Recurrent Disease during Herpes Simplex Virus 2 Infection

(2012) A. Svensson et al.   JOURNAL OF VIROLOGY

A vaccine strategy that protects against genital herpes by establishing local memory T cells

(2012) Haina Shin et al.   NATURE

Efficacy Results of a Trial of a Herpes Simplex Vaccine

(2012) Robert B. Belshe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen

(2012) S. Ariotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation

(2012) L. K. Mackay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The efficacy of HSV-2 vaccines based on gD and gB is enhanced by the addition of ICP27

(2012) Helen Bright et al.   VACCINE

Nasal and skin delivery of IC31®-adjuvanted recombinant HSV-2 gD protein confers protection against genital herpes

(2012) Benjamin Wizel et al.   VACCINE

A Vaxfectin®-adjuvanted HSV-2 plasmid DNA vaccine is effective for prophylactic and therapeutic use in the guinea pig model of genital herpes

(2012) Ronald L. Veselenak et al.   VACCINE

The subcellular location of antigen expressed by adenoviral vectors modifies adaptive immunity but not dependency on cross-presenting dendritic cells

(2011) Petra Henning et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

HSV-2: in pursuit of a vaccine

(2011) Christine Johnston et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting the Vaginal Mucosa with Human Papillomavirus Pseudovirion Vaccines Delivering Simian Immunodeficiency Virus DNA

(2011) S. N. Gordon et al.   JOURNAL OF IMMUNOLOGY

Characterization of a Human Cervical CD4+ T Cell Subset Coexpressing Multiple Markers of HIV Susceptibility

(2011) L. R. McKinnon et al.   JOURNAL OF IMMUNOLOGY

The Kinetics of Mucosal Herpes Simplex Virus–2 Infection in Humans: Evidence for Rapid Viral-Host Interactions

(2011) Joshua T. Schiffer et al.   JOURNAL OF INFECTIOUS DISEASES

Mucosal delivery of human papillomavirus pseudovirus-encapsidated plasmids improves the potency of DNA vaccination

(2010) B S Graham et al.   Mucosal Immunology

Protection from Herpes Simplex Virus (HSV)–2 Infection with Replication‐Defective HSV‐2 or Glycoprotein D2 Vaccines in HSV‐1–Seropositive and HSV‐1–Seronegative Guinea Pigs

(2009) Yo Hoshino et al.   JOURNAL OF INFECTIOUS DISEASES

A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge

(2009) X Zhang et al.   Mucosal Immunology

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

The integrin  4 7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1

(2009) C. Cicala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herpes Simplex: Insights on Pathogenesis and Possible Vaccines

(2008) David M. Koelle et al.   Annual Review of Medicine

An estimate of the global prevalence and incidence of herpes simplex virus type 2 infection

(2008) Katharine Looker   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus

(2008) Norifumi Iijima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comparison of immunogenicity and protective efficacy of genital herpes vaccine candidates herpes simplex virus 2 dl5-29 and dl5-29-41L in mice and guinea pigs

(2008) Yo Hoshino et al.   VACCINE