A Novel DNA Vaccine Technology Conveying Protection against a Lethal Herpes Simplex Viral Challenge in Mice

A Herpes Simplex Virus 2 Glycoprotein D Mutant Generated by Bacterial Artificial Chromosome Mutagenesis Is Severely Impaired for Infecting Neuronal Cells and Infects Only Vero Cells Expressing Exogenous HVEM

(2012) K. Wang et al.   JOURNAL OF VIROLOGY

Live Attenuated Herpes Simplex Virus 2 Glycoprotein E Deletion Mutant as a Vaccine Candidate Defective in Neuronal Spread

(2012) Sita Awasthi et al.   JOURNAL OF VIROLOGY

A vaccine strategy that protects against genital herpes by establishing local memory T cells

(2012) Haina Shin et al.   NATURE

Efficacy Results of a Trial of a Herpes Simplex Vaccine

(2012) Robert B. Belshe et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Vaxfectin®-adjuvanted HSV-2 plasmid DNA vaccine is effective for prophylactic and therapeutic use in the guinea pig model of genital herpes

(2012) Ronald L. Veselenak et al.   VACCINE

Herpes simplex virus-2 in the genital mucosa

(2011) Amanda J. Lee et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Immunization with DNA Vaccine Expressing Herpes Simplex Virus Type 1 gD and IL-21 Protects against Mouse Herpes Keratitis

(2011) Kai Hu et al.   IMMUNOLOGICAL INVESTIGATIONS

HSV-2: in pursuit of a vaccine

(2011) Christine Johnston et al.   JOURNAL OF CLINICAL INVESTIGATION

A Live-Attenuated HSV-2 ICP0− Virus Elicits 10 to 100 Times Greater Protection against Genital Herpes than a Glycoprotein D Subunit Vaccine

(2011) William P. Halford et al.   PLoS One

A heat shock protein based polyvalent vaccine targeting HSV-2: CD4+ and CD8+ cellular immunity and protective efficacy

(2011) Annie Mo et al.   VACCINE

Identification of B- and T-cell epitopes from glycoprotein B of herpes simplex virus 2 and evaluation of their immunogenicity and protection efficacy

(2011) Kun Liu et al.   VACCINE

Structure of Herpes Simplex Virus Glycoprotein D Bound to the Human Receptor Nectin-1

(2011) Paolo Di Giovine et al.   PLoS Pathogens

Genetic immunization based on the ubiquitin-fusion degradation pathway against Trypanosoma cruzi

(2010) Bin Chou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine (Gardasil®)

(2010) Paul L. McCormack et al.   DRUGS

DNA vaccine delivery by densely-packed and short microprojection arrays to skin protects against vaginal HSV-2 challenge

(2010) Angela Shaulov Kask et al.   VACCINE

Herpes simplex virus type 2 tegument proteins contain subdominant T-cell epitopes detectable in BALB/c mice after DNA immunization and infection

(2009) W. J. Muller et al.   JOURNAL OF GENERAL VIROLOGY

Interference of porcine circovirus type 2 ORF2 immunogenicity by ORF1 and ORF3 mixed DNA immunizations in mice

(2009) Hui-Gang Shen et al.   VIROLOGY

Herpes Simplex: Insights on Pathogenesis and Possible Vaccines

(2008) David M. Koelle et al.   Annual Review of Medicine

An estimate of the global prevalence and incidence of herpes simplex virus type 2 infection

(2008) Katharine Looker   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus

(2008) Norifumi Iijima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A recombinant plasmid co-expressing swine ubiquitin and the GP5 encoding-gene of porcine reproductive and respiratory syndrome virus induces protective immunity in piglets

(2008) Yan-Hong Hou et al.   VACCINE

Prime-boost vaccination with a combination of proteosome-degradable and wild-type forms of two influenza proteins leads to augmented CTL response

(2008) P.O. Ilyinskii et al.   VACCINE