Endocannabinoids are conserved inhibitors of the Hedgehog pathway

Wing tips: The wing disc as a platform for studying Hedgehog signaling

(2014) Tom A. Hartl et al.   METHODS

Canonical and non-canonical Hedgehog signalling and the control of metabolism

(2014) Raffaele Teperino et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Hedgehog Pathway Modulation by Multiple Lipid Binding Sites on the Smoothened Effector of Signal Response

(2013) Benjamin R. Myers et al.   DEVELOPMENTAL CELL

Structure of the human smoothened receptor bound to an antitumour agent

(2013) Chong Wang et al.   NATURE

Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling

(2013) Daniel Nedelcu et al.   Nature Chemical Biology

Unraveling the therapeutic potential of the Hedgehog pathway in cancer

(2013) Dereck Amakye et al.   NATURE MEDICINE

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hedgehog Signaling Controls T Cell Killing at the Immunological Synapse

(2013) M. de la Roche et al.   SCIENCE

Secretion and Signaling Activities of Lipoprotein-Associated Hedgehog and Non-Sterol-Modified Hedgehog in Flies and Mammals

(2013) Wilhelm Palm et al.   PLOS BIOLOGY

Small molecule inhibitors of the hedgehog signaling pathway for the treatment of cancer

(2012) Jeong In Yun et al.   ARCHIVES OF PHARMACAL RESEARCH

The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action

(2012) Laurie Hamtiaux et al.   BMC CANCER

Hedgehog Partial Agonism Drives Warburg-like Metabolism in Muscle and Brown Fat

(2012) Raffaele Teperino et al.   CELL

The Link between the Metabolic Syndrome and Cancer

(2012) Sandra Braun et al.   International Journal of Biological Sciences

Oxysterols are allosteric activators of the oncoprotein Smoothened

(2012) Sigrid Nachtergaele et al.   Nature Chemical Biology

HEDGEHOG-GLI Signaling Drives Self-Renewal and Tumorigenicity of Human Melanoma-Initiating Cells

(2012) Roberta Santini et al.   STEM CELLS

Skeletal lipidomics: regulation of bone metabolism by fatty acid amide family

(2011) Itai Bab et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hedgehog Signaling Regulates Nociceptive Sensitization

(2011) Daniel T. Babcock et al.   CURRENT BIOLOGY

Molecular mechanisms of maternal cannabis and cigarette use on human neurodevelopment

(2011) Claudia V. Morris et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Estimation of reference intervals of five endocannabinoids and endocannabinoid related compounds in human plasma by two dimensional-LC/MS/MS

(2011) Flaminia Fanelli et al.   JOURNAL OF LIPID RESEARCH

Mechanisms and functions of Hedgehog signalling across the metazoa

(2011) Philip W. Ingham et al.   NATURE REVIEWS GENETICS

Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator

(2010) X Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Drosophila Genome-wide Obesity Screen Reveals Hedgehog as a Determinant of Brown versus White Adipose Cell Fate

(2010) J. Andrew Pospisilik et al.   CELL

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

(2010) R. G. Pertwee et al.   PHARMACOLOGICAL REVIEWS

Hedgehog signalling: Emerging evidence for non-canonical pathways

(2009) Dagan Jenkins   CELLULAR SIGNALLING

Patched regulates Smoothened trafficking using lipoprotein-derived lipids

(2009) H. Khaliullina et al.   DEVELOPMENT

Evidence for Allosteric Interactions of Antagonist Binding to the Smoothened Receptor

(2009) C. M. Rominger et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation

(2009) Yu Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hedgehog signal transduction by Smoothened: Pharmacologic evidence for a 2-step activation process

(2009) R. Rohatgi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocannabinoids in endocrine and related tumours

(2008) M. Bifulco et al.   ENDOCRINE-RELATED CANCER

Pharmacological Synergism Between Cannabinoids and Paclitaxel in Gastric Cancer Cell Lines

(2008) Hideyo Miyato et al.   JOURNAL OF SURGICAL RESEARCH