11C-PBR28 imaging in multiple sclerosis patients and healthy controls: test-retest reproducibility and focal visualization of active white matter areas

Role of Translocator Protein Density, a Marker of Neuroinflammation, in the Brain During Major Depressive Episodes

(2015) Elaine Setiawan et al.   JAMA Psychiatry

Astrocytosis measured by 11C-deprenyl PET correlates with decrease in gray matter density in the parahippocampus of prodromal Alzheimer’s patients

(2014) IL Han Choo et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Determination of [11C]PBR28 Binding Potential in vivo: A First Human TSPO Blocking Study

(2014) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial

(2014) Jeremy Chataway et al.   LANCET

Functional pattern of brain FDG-PET in amyotrophic lateral sclerosis

(2014) M. Pagani et al.   NEUROLOGY

In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease

(2013) William C. Kreisl et al.   BRAIN

The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: A [11C]PBR28 PET study

(2013) Jonas Hannestad et al.   BRAIN BEHAVIOR AND IMMUNITY

Influence of TSPO Genotype on 11C-PBR28 Standardized Uptake Values

(2013) K. K. Yoder et al.   JOURNAL OF NUCLEAR MEDICINE

Quantification of the Specific Translocator Protein Signal of 18F-PBR111 in Healthy Humans: A Genetic Polymorphism Effect on In Vivo Binding

(2013) Q. Guo et al.   JOURNAL OF NUCLEAR MEDICINE

A Genetic Polymorphism for Translocator Protein 18 Kda Affects both in Vitro and in Vivo Radioligand Binding in Human Brain to this Putative Biomarker of Neuroinflammation

(2012) William C Kreisl et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Identifying improved TSPO PET imaging probes through biomathematics: The impact of multiple TSPO binding sites in vivo

(2012) Qi Guo et al.   NEUROIMAGE

Kinetic analysis and test-retest variability of the radioligand [11C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects

(2012) Aurelija Jučaite et al.   EJNMMI Research

Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

(2011) Chris H. Polman et al.   ANNALS OF NEUROLOGY

Segmentation of multiple sclerosis lesions in brain MRI: A review of automated approaches

(2011) Xavier Lladó et al.   INFORMATION SCIENCES

An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28

(2011) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Comparison of 18F- and 11C-labeled aryloxyanilide analogs to measure translocator protein in human brain using positron emission tomography

(2010) Leah P. Dickstein et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Two Binding Sites for [3H]PBR28 in Human Brain: Implications for TSPO PET Imaging of Neuroinflammation

(2010) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Translocator Protein PET Imaging for Glial Activation in Multiple Sclerosis

(2010) Unsong Oh et al.   Journal of Neuroimmune Pharmacology

Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands

(2010) D. R. J. Owen et al.   JOURNAL OF NUCLEAR MEDICINE

Grey matter pathology in clinically early multiple sclerosis: Evidence from magnetic resonance imaging

(2009) Declan Chard et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Comparison of [11C]-(R)-PK 11195 and [11C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker

(2009) William C. Kreisl et al.   NEUROIMAGE

Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures

(2009) E. M. Mowry et al.   NEUROLOGY

Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

(2008) M. Cosenza-Nashat et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation

(2007) Masahiro Fujita et al.   NEUROIMAGE