Impact of carbon nanotubes and graphene on immune cells

Non-BRAF-targeted therapy, immunotherapy, and combination therapy for melanoma

(2014) Sara Tomei et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Graphene Oxide Induces Toll-like Receptor 4 (TLR4)-Dependent Necrosis in Macrophages

(2013) Guangbo Qu et al.   ACS Nano

Surface Charge and Cellular Processing of Covalently Functionalized Multiwall Carbon Nanotubes Determine Pulmonary Toxicity

(2013) Ruibin Li et al.   ACS Nano

Graphene: Safe or Toxic? The Two Faces of the Medal

(2013) Alberto Bianco   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The immunotoxicity of graphene oxides and the effect of PVP-coating

(2013) Xiao Zhi et al.   BIOMATERIALS

Functionalized carbon nanotubes as immunomodulator systems

(2013) Mario Pescatori et al.   BIOMATERIALS

CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2

(2013) D Bedognetti et al.   BRITISH JOURNAL OF CANCER

The Continuum of Cancer Immunosurveillance: Prognostic, Predictive, and Mechanistic Signatures

(2013) Jérôme Galon et al.   IMMUNITY

Purification and sidewall functionalization of multiwalled carbon nanotubes and resulting bioactivity in two macrophage models

(2013) Raymond F. Hamilton et al.   INHALATION TOXICOLOGY

Selective Pathogen Targeting and Macrophage Evading Carbon Nanotubes Through Dextran Sulfate Coating and PEGylation for Photothermal Theranostics

(2013) Nalinikanth Kotagiri et al.   Journal of Biomedical Nanotechnology

Structural profiling and biological performance of phospholipid–hyaluronan functionalized single-walled carbon nanotubes

(2013) Ram Dvash et al.   JOURNAL OF CONTROLLED RELEASE

Evidencing the mask effect of graphene oxide: a comparative study on primary human and murine phagocytic cells

(2013) Julie Russier et al.   Nanoscale

Modulation of Apoptotic Pathways of Macrophages by Surface-Functionalized Multi-Walled Carbon Nanotubes

(2013) Yuanqin Jiang et al.   PLoS One

Graphene microsheets enter cells through spontaneous membrane penetration at edge asperities and corner sites

(2013) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conservation and divergence in the transcriptional programs of the human and mouse immune systems

(2013) T. Shay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functionalization of Carbon Nanoparticles Modulates Inflammatory Cell Recruitment and NLRP3 Inflammasome Activation

(2013) Marie Yang et al.   Small

Single-walled carbon nanotubes and graphene oxides induce autophagosome accumulation and lysosome impairment in primarily cultured murine peritoneal macrophages

(2013) Bin Wan et al.   TOXICOLOGY LETTERS

Confocal Raman Imaging Study Showing Macrophage Mediated Biodegradation of Graphene In Vivo

(2013) Chundayil Madathil Girish et al.   Advanced Healthcare Materials

Carbon nanotubes as a novel tool for vaccination against infectious diseases and cancer

(2013) Riccardo Gottardi et al.   JOURNAL OF NANOBIOTECHNOLOGY

A high poly(ethylene glycol) density on graphene nanomaterials reduces the detachment of lipid–poly(ethylene glycol) and macrophage uptake

(2012) Mei Yang et al.   Acta Biomaterialia

The role of the lateral dimension of graphene oxide in the regulation of cellular responses

(2012) Hua Yue et al.   BIOMATERIALS

The interactions between pristine graphene and macrophages and the production of cytokines/chemokines via TLR- and NF-κB-related signaling pathways

(2012) Hejiang Zhou et al.   BIOMATERIALS

Simultaneous induction of autophagy and toll-like receptor signaling pathways by graphene oxide

(2012) Guan-Yu Chen et al.   BIOMATERIALS

The effects of graphene oxide nanosheets localized on F-actin filaments on cell-cycle alterations

(2012) María-Concepción Matesanz et al.   BIOMATERIALS

Efficient and rapid uptake of magnetic carbon nanotubes into human monocytic cells: implications for cell-based cancer gene therapy

(2012) Hilal Gul-Uludag et al.   BIOTECHNOLOGY LETTERS

Graphene oxide absorbed anti-IL10R antibodies enhance LPS induced immune responses in vitro and in vivo

(2012) Guoying Ni et al.   IMMUNOLOGY LETTERS

Comparison of Cytotoxicity of Pristine and Covalently Functionalized Multi-Walled Carbon Nanotubes in RAW 264.7 Macrophages

(2012) Man Luo et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Water-Soluble Taurine-Functionalized Multi-Walled Carbon Nanotubes Induce Less Damage to Mitochondria of RAW 264.7 Cells

(2012) Tian Chen et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Tailoring 3D Single-Walled Carbon Nanotubes Anchored to Indium Tin Oxide for Natural Cellular Uptake and Intracellular Sensing

(2012) F. J. Rawson et al.   NANO LETTERS

Advances in molecular imaging: targeted optical contrast agents for cancer diagnostics

(2012) Anne Hellebust et al.   Nanomedicine

Nanoparticles as computed tomography contrast agents: current status and future perspectives

(2012) Malka Shilo et al.   Nanomedicine

Functionalized multiwalled carbon nanotubes as ultrasound contrast agents

(2012) L. G. Delogu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small-Sized Carbon Nanohorns Enabling Cellular Uptake Control

(2012) Minfang Zhang et al.   Small

Adsorption of Multimeric T Cell Antigens on Carbon Nanotubes: Effect on Protein Structure and Antigen-Specific T Cell Stimulation

(2012) Tarek R. Fadel et al.   Small

Hemocompatibility and Macrophage Response of Pristine and Functionalized Graphene

(2012) Abhilash Sasidharan et al.   Small

Steering Carbon Nanotubes to Scavenger Receptor Recognition by Nanotube Surface Chemistry Modification Partially Alleviates NFκB Activation and Reduces Its Immunotoxicity

(2011) Ningning Gao et al.   ACS Nano

Direct Effects of Carbon Nanotubes on Dendritic Cells Induce Immune Suppression Upon Pulmonary Exposure

(2011) Alexey V. Tkach et al.   ACS Nano

Dispersal State of Multiwalled Carbon Nanotubes Elicits Profibrogenic Cellular Responses That Correlate with Fibrogenesis Biomarkers and Fibrosis in the Murine Lung

(2011) Xiang Wang et al.   ACS Nano

Graphene-Based Nanoplatelets: A New Risk to the Respiratory System as a Consequence of Their Unusual Aerodynamic Properties

(2011) Anja Schinwald et al.   ACS Nano

Tunable chemistry and morphology of multi-wall carbon nanotubes as a route to non-toxic, theranostic systems

(2011) Sławomir Boncel et al.   BIOMATERIALS

The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways

(2011) Yang Li et al.   BIOMATERIALS

Lysosomal membrane destabilization induced by high accumulation of single-walled carbon nanohorns in murine macrophage RAW 264.7

(2011) Yoshio Tahara et al.   BIOMATERIALS

Making carbon nanotubes biocompatible and biodegradable

(2011) Alberto Bianco et al.   CHEMICAL COMMUNICATIONS

Targeted killing of Leishmania donovani in vivo and in vitro with amphotericin B attached to functionalized carbon nanotubes

(2011) V. K. Prajapati et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of the Interactions Between Multiwalled Carbon Nanotubes and Caco-2 Cells

(2011) Katherine A. Clark et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesis

(2011) Tara L Spivey et al.   Journal of Translational Medicine

An immunologic portrait of cancer

(2011) Maria Ascierto et al.   Journal of Translational Medicine

SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document: Online resources and useful tools - a compass in the land of biomarker discovery

(2011) Davide Bedognetti et al.   Journal of Translational Medicine

Study of hepatotoxicity and oxidative stress in male Swiss-Webster mice exposed to functionalized multi-walled carbon nanotubes

(2011) Anita K. Patlolla et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Ex vivo impact of functionalized carbon nanotubes on human immune cells

(2011) Lucia Gemma Delogu et al.   Nanomedicine

Cytotoxicity of functionalized carbon nanotubes in J774A macrophages

(2011) Silvia Lorena Montes-Fonseca et al.   Nanomedicine-Nanotechnology Biology and Medicine

Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation

(2011) Etienne Meunier et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cellular uptake mechanisms of functionalised multi-walled carbon nanotubes by 3D electron tomography imaging

(2011) Khuloud T. Al-Jamal et al.   Nanoscale

Histological assessments for toxicity and functionalization-dependent biodistribution of carbon nanohorns

(2011) Yoshio Tahara et al.   NANOTECHNOLOGY

In vitrotoxicity of acid-functionalized single-walled carbon nanotubes: Effects on murine macrophages and gene expression profiling

(2011) Ping-Xuan Dong et al.   Nanotoxicology

Coating carbon nanotubes with a polystyrene-based polymer protects against pulmonary toxicity

(2011) Lyes Tabet et al.   Particle and Fibre Toxicology

FeCo/Graphite Nanocrystals for Multi-Modality Imaging of Experimental Vascular Inflammation

(2011) Hisanori Kosuge et al.   PLoS One

Carbon Nanotubes Enhance Cytotoxicity Mediated by Human Lymphocytes In Vitro

(2011) Zhao Sun et al.   PLoS One

Oxidized Ultrashort Nanotubes as Carbon Scaffolds for the Construction of Cell-Penetrating NF-κB Decoy Molecules

(2010) Rita Crinelli et al.   ACS Nano

Antifungal Activity of Amphotericin B Conjugated to Carbon Nanotubes

(2010) Monica Benincasa et al.   ACS Nano

Carbon Nanotubes Enhance CpG Uptake and Potentiate Antiglioma Immunity

(2010) D. Zhao et al.   CLINICAL CANCER RESEARCH

Dispersion state and toxicity of mwCNTs in cell culture medium with different T80 concentrations

(2010) Ahmet C. Sabuncu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Autoimmune-associated PTPN22 R620W Variation Reduces Phosphorylation of Lymphoid Phosphatase on an Inhibitory Tyrosine Residue

(2010) Edoardo Fiorillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carbon Nanotube-Based Nanocarriers: The Importance of Keeping It Clean

(2010) Lucia G. Delogu et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Water Soluble Multi-Walled Carbon Nanotubes Enhance Peritoneal Macrophage Activity In Vivo

(2010) Xiaoyong Deng et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Advancement in carbon nanotubes: basics, biomedical applications and toxicity

(2010) Sarwar Beg et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Toxicity and Clearance of Intratracheally Administered Multiwalled Carbon Nanotubes from Murine Lung

(2010) Ji-Eun Kim et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

New Insights of Transmembranal Mechanism and Subcellular Localization of Noncovalently Modified Single-Walled Carbon Nanotubes

(2010) Feifan Zhou et al.   NANO LETTERS

Improved cellular uptake of functionalized single-walled carbon nanotubes

(2010) A Antonelli et al.   NANOTECHNOLOGY

Immune responses of BALB/c mice to subcutaneously injected multi-walled carbon nanotubes

(2010) Jie Meng et al.   Nanotoxicology

Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation

(2010) Valerian E. Kagan et al.   Nature Nanotechnology

In vitro evaluation of cytotoxicity of engineered carbon nanotubes in selected human cell lines

(2010) Xiaoke Hu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Uptake of Noncytotoxic Acid-Treated Single-Walled Carbon Nanotubes into the Cytoplasm of Human Macrophage Cells

(2009) Alexandra E. Porter et al.   ACS Nano

Conjugation of Antisense Oligonucleotides to PEGylated Carbon Nanotubes Enables Efficient Knockdown of PTPN22 in T Lymphocytes

(2009) Lucia G. Delogu et al.   BIOCONJUGATE CHEMISTRY

Immunological and cytotoxicological characterization of tuberculin purified protein derivative (PPD) conjugated to single-walled carbon nanotubes

(2009) Majid Zeinali et al.   IMMUNOLOGY LETTERS

Genotoxic Properties of Nylon-6/MWNTs Nanohybrid

(2009) Omar E. Ochoa-Olmos et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Selective uptake of multi-walled carbon nanotubes by tumor macrophages in a murine glioma model

(2009) Michelle VanHandel et al.   JOURNAL OF NEUROIMMUNOLOGY

Clustering of Stimuli on Single-Walled Carbon Nanotube Bundles Enhances Cellular Activation

(2009) Tarek R. Fadel et al.   LANGMUIR

Nanomedicine for the management of lung and blood diseases

(2009) Denis B Buxton   Nanomedicine

Using carbon nanotubes to induce micronuclei and double strand breaks of the DNA in human cells

(2009) Jelena Cveticanin et al.   NANOTECHNOLOGY

Evaluation of nanoparticle immunotoxicity

(2009) Marina A. Dobrovolskaia et al.   Nature Nanotechnology

Promises, facts and challenges for carbon nanotubes in imaging and therapeutics

(2009) K. Kostarelos et al.   Nature Nanotechnology

Phosphatidylserine Targets Single-Walled Carbon Nanotubes to Professional Phagocytes In Vitro and In Vivo

(2009) Nagarjun V. Konduru et al.   PLoS One

The phagocytes: neutrophils and monocytes

(2008) D. C. Dale et al.   BLOOD

Cell-Type Specific and Cytoplasmic Targeting of PEGylated Carbon Nanotube-Based Nanoassemblies

(2008) Matthew H. Cato et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Single-Walled Carbon Nanotubes Can Induce Pulmonary Injury in Mouse Model

(2008) Cheng-Chung Chou et al.   NANO LETTERS

Enhanced Cellular Activation with Single Walled Carbon Nanotube Bundles Presenting Antibody Stimuli

(2008) Tarek R. Fadel et al.   NANO LETTERS

A pilot toxicology study of single-walled carbon nanotubes in a small sample of mice

(2008) Meike L. Schipper et al.   Nature Nanotechnology

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology