Differential immunomodulatory effects by Tripterygium wilfordii Hook f-derived refined extract PG27 and its purified component PG490 (triptolide) in human peripheral blood T cells: potential therapeutics for arthritis and possible mechanisms explaining in part Chinese herbal theory “Junn-Chenn-Zuou-SS”

Comparison ofTripterygium wilfordiiHook F Versus Sulfasalazine in the Treatment of Rheumatoid Arthritis

(2013) Raphaela Goldbach-Mansky   ANNALS OF INTERNAL MEDICINE

Therapies for Active Rheumatoid Arthritis after Methotrexate Failure

(2013) James R. O'Dell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2011

(2012) D E Furst et al.   ANNALS OF THE RHEUMATIC DISEASES

Triptolide in the treatment of psoriasis and other immune-mediated inflammatory diseases

(2012) Rui Han et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Regulation of NF-κB by ubiquitination and degradation of the IκBs

(2012) Naama Kanarek et al.   IMMUNOLOGICAL REVIEWS

It takes two to tango: IκBs, the multifunctional partners of NF-κB

(2012) Michael Hinz et al.   IMMUNOLOGICAL REVIEWS

Triptolide: structural modifications, structure–activity relationships, bioactivities, clinical development and mechanisms

(2012) Zhao-Li Zhou et al.   NATURAL PRODUCT REPORTS

Targeting of TAK1 in inflammatory disorders and cancer

(2012) Hiroaki Sakurai   TRENDS IN PHARMACOLOGICAL SCIENCES

Targeting inflammation by modulating the Jun/AP-1 pathway

(2011) H. B. Schonthaler et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-TNF therapy

(2011) Nishanthi Thalayasingam et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Novel IκB kinase inhibitors for treatment of nuclear factor-κB-related diseases

(2011) Jun-Ichi Suzuki et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Triptolide Inhibits IL-12/IL-23 Expression in APCs via CCAAT/Enhancer-Binding Protein  

(2010) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Gene discovery in rheumatoid arthritis highlights the CD40/NF-ĸB signaling pathway in disease pathogenesis

(2009) Lindsey A. Criswell   IMMUNOLOGICAL REVIEWS

Effects of triptolide from Tripterygium wilfordii on ERα and p53 expression in two human breast cancer cell lines

(2009) Jing Liu et al.   PHYTOMEDICINE