Use of a mouse model to elucidate the phenotypic effects of the von Willebrand factor cleavage mutants, Y1605A/M1606A and R1597W

Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models

(2011) C. M. Pruss et al.   BLOOD

Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions

(2010) M. Golder et al.   BLOOD

Mutation and ADAMTS13-dependent modulation of disease severity in a mouse model for von Willebrand disease type 2B

(2010) J. Rayes et al.   BLOOD

The ADAMTS13 metalloprotease domain: roles of subsites in enzyme activity and specificity

(2010) R. de Groot et al.   BLOOD

Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site

(2009) T. J. Raife et al.   BLOOD

Species-dependent variability of ADAMTS13-mediated proteolysis of human recombinant von Willebrand factor

(2009) K. VARADI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor

(2009) Q. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor

(2009) X. Zhang et al.   SCIENCE

Altered thrombus formation in von Willebrand factor-deficient mice expressing von Willebrand factor variants with defective binding to collagen or GPIIbIIIa

(2008) I. Marx et al.   BLOOD

The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation

(2008) F. Banno et al.   BLOOD

Thrombospondin-1 in Von Willebrand Factor Function

(2008) Arnaud Bonnefoy et al.   CURRENT DRUG TARGETS