Protein misfolding in Dictyostelium: Using a freak of nature to gain insight into a universal problem

Asparagine Repeat Peptides: Aggregation Kinetics and Comparison with Glutamine Repeats

(2015) Xiaomeng Lu et al.   BIOCHEMISTRY

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Yeast Prions: Structure, Biology, and Prion-Handling Systems

(2015) Reed B. Wickner et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Variable Glutamine-Rich Repeats Modulate Transcription Factor Activity

(2015) Rita Gemayel et al.   MOLECULAR CELL

Dictyostelium discoideumhas a highly Q/N-rich proteome and shows an unusual resilience to protein aggregation

(2015) Liliana Malinovska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From nucleation to widespread propagation: A prion-like concept for ALS

(2015) Zuzanna Maniecka et al.   VIRUS RESEARCH

Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

(2015) Sonja Kroschwald et al.   eLife

Self-propagating amyloid as a critical regulator for diverse cellular functions

(2014) S. Sugiyama et al.   JOURNAL OF BIOCHEMISTRY

Ubiquitin–proteasome system involvement in Huntington’s disease

(2014) Zaira Ortega et al.   Frontiers in Molecular Neuroscience

PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone

(2013) Sae-Hun Park et al.   CELL

Intranuclear Aggregation of Mutant FUS/TLS as a Molecular Pathomechanism of Amyotrophic Lateral Sclerosis

(2013) Takao Nomura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

A decade and a half of protein intrinsic disorder: Biology still waits for physics

(2013) Vladimir N. Uversky   PROTEIN SCIENCE

Characterization of the oligomerization and ligand-binding properties of recombinant rat lipocalin 11

(2012) Yina Gu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

(2012) Oliver D. King et al.   BRAIN RESEARCH

Prions in Yeast

(2012) S. W. Liebman et al.   GENETICS

Prions are a common mechanism for phenotypic inheritance in wild yeasts

(2012) Randal Halfmann et al.   NATURE

Nucleolar aggresomes as counterparts of cytoplasmic aggresomes in proteotoxic stress

(2011) Leena Latonen   BIOESSAYS

The Cellular Basis for Animal Regeneration

(2011) Elly M. Tanaka et al.   DEVELOPMENTAL CELL

Cell condition, competition, and chimerism in the social amoebaDictyostelium discoideum

(2011) D.I. Castillo et al.   ETHOLOGY ECOLOGY & EVOLUTION

Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered Proteins

(2011) Randal Halfmann et al.   MOLECULAR CELL

RNA-binding proteins with prion-like domains in ALS and FTLD-U

(2011) Aaron D. Gitler et al.   Prion